An NK-like CAR T cell transition in CAR T cell dysfunction CR Good, MA Aznar, S Kuramitsu, P Samareh, S Agarwal, G Donahue, ... Cell 184 (25), 6081-6100. e26, 2021 | 211 | 2021 |
Application of traditional vaccine development strategies to SARS-CoV-2 HM Rando, R Lordan, AJ Lee, A Naik, N Wellhausen, E Sell, L Kolla, ... Msystems 8 (2), e00927-22, 2023 | 10 | 2023 |
Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy N Wellhausen, S Agarwal, PC Rommel, SI Gill, CH June Current opinion in immunology 74, 76-84, 2022 | 15 | 2022 |
Combination therapy for solid tumors: taking a classic CAR on new adventures O Dagher, TR King, N Wellhausen, AD Posey Cancer Cell 38 (5), 621-623, 2020 | 8 | 2020 |
Correction for Rando et al.,“Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure” HM Rando, AL MacLean, AJ Lee, R Lordan, S Ray, V Bansal, AN Skelly, ... Msystems 7 (1), e01447-21, 2022 | | 2022 |
Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19 LA Vella, JR Giles, AE Baxter, DA Oldridge, C Diorio, L Kuri-Cervantes, ... Science immunology 6 (57), eabf7570, 2021 | 206 | 2021 |
Engineered pan-leukocyte antigen cd45 to facilitate car t cell therapy NW Saar Gill, Carl H. June WO Patent WO2023091954A3, 2023 | | 2023 |
Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Δ133p53α C Roselle, I Horikawa, L Chen, AR Kelly, D Gonzales, T Da, ... Proceedings of the National Academy of Sciences 121 (10), e2317735121, 2024 | 2 | 2024 |
Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy N Wellhausen, RP O’Connell, S Lesch, NW Engel, AK Rennels, ... Science translational medicine 15 (714), eadi1145, 2023 | 29 | 2023 |
Epitope editing in hematopoietic cells enables CD45-directed immune therapy N Wellhausen, AK Rennels, S Lesch, S Agarwal, B Charria, G Choi, ... Blood 140 (Supplement 1), 862-864, 2022 | 7 | 2022 |
EPITOPE EDITING IN HEMATOPOIETIC CELLS ENABLES PROTECTION FROM CD45-DIRECTED IMMUNOTHERAPIES FOR THE TREATMENT OF BLOOD CANCERS AND BEYOND N Wellhausen University of Pennsylvania, 2024 | | 2024 |
Format-tuning of in vivo-launched bispecific T cell engager enhances efficacy against renal cell carcinoma RP O’Connell, K Liaw, N Wellhausen, CA Chuckran, PS Bhojnagarwala, ... Journal for Immunotherapy of Cancer 12 (6), 2024 | | 2024 |
Glycans as Targets and Mediators of T-Cell Immunotherapy N Wellhausen, W Aguilar, AD Posey Jr Elsevier, 2021 | | 2021 |
Identification and development of therapeutics for COVID-19 HM Rando, N Wellhausen, S Ghosh, AJ Lee, AA Dattoli, F Hu, JB Byrd, ... Msystems 6 (6), e00233-21, 2021 | 20 | 2021 |
Identification and Development of Therapeutics for COVID-19 N Wellhausen, S Ghosh, AJ Lee, AA Dattoli, F Hu | | |
Identification of core techniques that enhance genome editing of human T cells expressing synthetic antigen receptors JF Chang, N Wellhausen, NW Engel, JH Landmann, CR Hopkins, ... Cancer Immunology Research, 2024 | | 2024 |
Induction of a CD8 T cell intrinsic DNA damage and repair response is associated with clinical response to PD-1 blockade in uterine cancer Y Muroyama, S Manne, N Wellhausen, DA Oldridge, AR Greenplate, ... bioRxiv, 2022.04. 16.488552, 2022 | 4 | 2022 |
Induction of T cell dysfunction and NK-like T cell differentiation in vitro and in patients after CAR T cell treatment CR Good, S Kuramitsu, P Samareh, G Donahue, K Ishiyama, Y Ma, ... Cancer Research 81 (13_Supplement), 60-60, 2021 | 1 | 2021 |
LIPID NANOPARTICLES ENABLE EFFICIENT BASE EDITING OF CD45-DIRECTED CAR T CELLS FOR UNIVERSAL BLOOD CANCER IMMUNOTHERAPY EK Ghahe, N Wellhausen, R Geczy, A Balgi, S Clarke, C June, S Gill, ... Cytotherapy 26 (6), S212, 2024 | | 2024 |
Mechanisms of CAR T cell dysfunction and identification of transcription factors that drive the exhaustion phenotype MA Aznar, CR Good, S Kuramitsu, P Samareh, S Agarwal, G Donahue, ... Cancer Research 82 (12_Supplement), 3602-3602, 2022 | | 2022 |