A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses AZ Wec, EK Nyakatura, AS Herbert, KA Howell, FW Holtsberg, RR Bakken, ... Science 354 (6310), 350-354, 2016 | 128 | 2016 |
A hyperstabilizing mutation in the base of the Ebola virus glycoprotein acts at multiple steps to abrogate viral entry JM Fels, JS Spence, RH Bortz III, ZA Bornholdt, K Chandran MBio 10 (4), 10.1128/mbio. 01408-19, 2019 | 12 | 2019 |
A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates ZA Bornholdt, AS Herbert, CE Mire, S He, RW Cross, AZ Wec, ... Cell host & microbe 25 (1), 49-58. e5, 2019 | 95 | 2019 |
Analytical validation of the ReEBOV antigen rapid test for point-of-care diagnosis of Ebola virus infection RW Cross, ML Boisen, MM Millett, DS Nelson, D Oottamasathien, ... The Journal of infectious diseases 214 (suppl_3), S210-S217, 2016 | 39 | 2016 |
Anti-crimean-congo hemorrhagic fever virus antibodies, and methods of their generation and use ZA Bornholdt, A Mishra, LM Walker, NT Pauli, D Maurer, K Chandran, ... US Patent App. 17/829,164, 2023 | | 2023 |
Anti-crimean-congo hemorrhagic fever virus antibodies, and methods of their generation and use ZA Bornholdt, A Mishra, LM Walker, NT Pauli, D Maurer, K Chandran, ... US Patent App. 17/308,753, 2021 | | 2021 |
Antibodies from a human survivor define sites of vulnerability for broad protection against ebolaviruses AZ Wec, AS Herbert, CD Murin, EK Nyakatura, DM Abelson, JM Fels, ... Cell 169 (5), 878-890. e15, 2017 | 158 | 2017 |
Antibody therapeutics for emerging infectious diseases: Ebola virus and others JM Dye, K Chandran, A Wec, L Walker, L Zeitlin, Z Bornholdt, A Herbert The Journal of Immunology 204 (1_Supplement), 167.21-167.21, 2020 | | 2020 |
Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins HV Dang, RW Cross, V Borisevich, ZA Bornholdt, BR West, YP Chan, ... Nature Structural & Molecular Biology 28 (5), 426-434, 2021 | 41 | 2021 |
Characterization of Bombali virus, a new bat filovirus L McMullan, M Flint, MH Jenks, LW Guerrero, AK Chakrabarti, ... | 3 | 2022 |
Clinical and Translational Report AZ Wec, ZA Bornholdt, S He, AS Herbert, E Goodwin, AS Wirchnianski, ... Cell Host & Microbe 25, 39-48, 2019 | | 2019 |
Combination therapy protects macaques against advanced Marburg virus disease RW Cross, ZA Bornholdt, AN Prasad, V Borisevich, KN Agans, DJ Deer, ... Nature communications 12 (1), 1891, 2021 | 48 | 2021 |
Combination therapy with remdesivir and monoclonal antibodies protects nonhuman primates against advanced Sudan virus disease RW Cross, ZA Bornholdt, AN Prasad, C Woolsey, V Borisevich, KN Agans, ... JCI insight 7 (10), 2022 | 23 | 2022 |
Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein MP Doyle, N Kose, V Borisevich, E Binshtein, M Amaya, M Nagel, ... Cell reports 36 (9), 2021 | 29 | 2021 |
Correction: The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold APP Zhang, ZA Bornholdt, T Liu, DM Abelson, DE Lee, S Li, VL Woods Jr, ... PLoS Pathogens 9 (12), 2013 | | 2013 |
Crystal structure of Marburg virus VP24 APP Zhang, ZA Bornholdt, DM Abelson, EO Saphire Journal of virology 88 (10), 5859-5863, 2014 | 30 | 2014 |
Crystal structure of Marburg virus VP40 reveals a broad, basic patch for matrix assembly and a requirement of the N-terminal domain for immunosuppression S Oda, T Noda, KJ Wijesinghe, P Halfmann, ZA Bornholdt, DM Abelson, ... Journal of virology 90 (4), 1839-1848, 2016 | 48 | 2016 |
Crystal structure of Marburg virus VP40: matrix assembly and immunosuppression SI Oda, T Noda, KJ Wijesinghe, P Halfmann, ZA Bornholdt, DM Abelson, ... J Virol, 2015 | 2 | 2015 |
Crystal structure of the Nipah virus phosphoprotein tetramerization domain DR Keegan, ZA Bornholdt, EO Saphire | | 2013 |
Crystal structure of the Nipah virus phosphoprotein tetramerization domain JF Bruhn, KC Barnett, J Bibby, JMH Thomas, RM Keegan, DJ Rigden, ... Journal of virology 88 (1), 758-762, 2014 | 93 | 2014 |