关注
Zachary A Bornholdt
Zachary A Bornholdt
Mapp Biopharmaceutical, Inc.
在 mappbio.com 的电子邮件经过验证
标题
引用次数
年份
A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses
AZ Wec, EK Nyakatura, AS Herbert, KA Howell, FW Holtsberg, RR Bakken, ...
Science 354 (6310), 350-354, 2016
1282016
A hyperstabilizing mutation in the base of the Ebola virus glycoprotein acts at multiple steps to abrogate viral entry
JM Fels, JS Spence, RH Bortz III, ZA Bornholdt, K Chandran
MBio 10 (4), 10.1128/mbio. 01408-19, 2019
122019
A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates
ZA Bornholdt, AS Herbert, CE Mire, S He, RW Cross, AZ Wec, ...
Cell host & microbe 25 (1), 49-58. e5, 2019
952019
Analytical validation of the ReEBOV antigen rapid test for point-of-care diagnosis of Ebola virus infection
RW Cross, ML Boisen, MM Millett, DS Nelson, D Oottamasathien, ...
The Journal of infectious diseases 214 (suppl_3), S210-S217, 2016
392016
Anti-crimean-congo hemorrhagic fever virus antibodies, and methods of their generation and use
ZA Bornholdt, A Mishra, LM Walker, NT Pauli, D Maurer, K Chandran, ...
US Patent App. 17/829,164, 2023
2023
Anti-crimean-congo hemorrhagic fever virus antibodies, and methods of their generation and use
ZA Bornholdt, A Mishra, LM Walker, NT Pauli, D Maurer, K Chandran, ...
US Patent App. 17/308,753, 2021
2021
Antibodies from a human survivor define sites of vulnerability for broad protection against ebolaviruses
AZ Wec, AS Herbert, CD Murin, EK Nyakatura, DM Abelson, JM Fels, ...
Cell 169 (5), 878-890. e15, 2017
1582017
Antibody therapeutics for emerging infectious diseases: Ebola virus and others
JM Dye, K Chandran, A Wec, L Walker, L Zeitlin, Z Bornholdt, A Herbert
The Journal of Immunology 204 (1_Supplement), 167.21-167.21, 2020
2020
Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins
HV Dang, RW Cross, V Borisevich, ZA Bornholdt, BR West, YP Chan, ...
Nature Structural & Molecular Biology 28 (5), 426-434, 2021
412021
Characterization of Bombali virus, a new bat filovirus
L McMullan, M Flint, MH Jenks, LW Guerrero, AK Chakrabarti, ...
32022
Clinical and Translational Report
AZ Wec, ZA Bornholdt, S He, AS Herbert, E Goodwin, AS Wirchnianski, ...
Cell Host & Microbe 25, 39-48, 2019
2019
Combination therapy protects macaques against advanced Marburg virus disease
RW Cross, ZA Bornholdt, AN Prasad, V Borisevich, KN Agans, DJ Deer, ...
Nature communications 12 (1), 1891, 2021
482021
Combination therapy with remdesivir and monoclonal antibodies protects nonhuman primates against advanced Sudan virus disease
RW Cross, ZA Bornholdt, AN Prasad, C Woolsey, V Borisevich, KN Agans, ...
JCI insight 7 (10), 2022
232022
Cooperativity mediated by rationally selected combinations of human monoclonal antibodies targeting the henipavirus receptor binding protein
MP Doyle, N Kose, V Borisevich, E Binshtein, M Amaya, M Nagel, ...
Cell reports 36 (9), 2021
292021
Correction: The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold
APP Zhang, ZA Bornholdt, T Liu, DM Abelson, DE Lee, S Li, VL Woods Jr, ...
PLoS Pathogens 9 (12), 2013
2013
Crystal structure of Marburg virus VP24
APP Zhang, ZA Bornholdt, DM Abelson, EO Saphire
Journal of virology 88 (10), 5859-5863, 2014
302014
Crystal structure of Marburg virus VP40 reveals a broad, basic patch for matrix assembly and a requirement of the N-terminal domain for immunosuppression
S Oda, T Noda, KJ Wijesinghe, P Halfmann, ZA Bornholdt, DM Abelson, ...
Journal of virology 90 (4), 1839-1848, 2016
482016
Crystal structure of Marburg virus VP40: matrix assembly and immunosuppression
SI Oda, T Noda, KJ Wijesinghe, P Halfmann, ZA Bornholdt, DM Abelson, ...
J Virol, 2015
22015
Crystal structure of the Nipah virus phosphoprotein tetramerization domain
DR Keegan, ZA Bornholdt, EO Saphire
2013
Crystal structure of the Nipah virus phosphoprotein tetramerization domain
JF Bruhn, KC Barnett, J Bibby, JMH Thomas, RM Keegan, DJ Rigden, ...
Journal of virology 88 (1), 758-762, 2014
932014
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