“Exhausted” T Cells: Good or Bad Depends on Your Point of View Restoring function in exhausted CD8 T cells during chronic viral infection. Barber DL EJ Wherry, D Masopust, B Zhu, JP Allison, AH Sharpe, GJ Freeman, ... liver transplantation 16 (1135), 2005 | | 2005 |
1016 Enforcement of exhausted T cell epigenetic fate by HMG-box transcription factor TOX YJ Huang, JR Giles, SF Ngiow, AE Baxter, S Manne, O Khan, SL Park, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
1337 Preclinical evaluation of STAR0602, a novel, first-in-class anti-TCR Vb targeted bispecific antibody with potent anti-tumor activity for PD-1 refractory solid tumors Z Su, J Gulley, J Schlom, L Siu, R Sullivan, EJ Wherry, K Liu, R Donahue, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
1522 Revitalizing systemic immune responses in progressive NSCLC using FLT3L and SBRT D Mathew, N Ohri, SF Ngiow, KC Wumesh, B Halmos, M Garg, JM Levsky, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 2), 2023 | | 2023 |
253 PD1 and LAG3 converge to limit polyfunctionality and systemic immunity L Andrews, S Manne, EJ Wherry, C Workman, D Vignali Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A274-A274, 2021 | | 2021 |
310 T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade Y Muroyama, S Manne, A Greenplate, D Mathew, D Oldridge, L Chilukuri, ... Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A335-A335, 2021 | | 2021 |
579-C Reinvigoration of progenitor-exhausted CD8 T cells by anti-CTLA-4 contributes to the sustained activity of combination checkpoint blockade K Wang, P Coutifaris, D Brocks, S Solis, N Han, S Manne, E Kiner, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 2), 2023 | | 2023 |
A boost with SARS-CoV-2 BNT162b2 mRNA vaccine elicits strong humoral responses independently of the interval between the first two doses A Tauzin, SY Gong, D Chatterjee, S Ding, MM Painter, RR Goel, ... Cell Reports 41 (4), 2022 | 16 | 2022 |
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A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells LP Andrews, KM Vignali, AL Szymczak-Workman, AR Burton, ... Immunity 54 (10), 2209-2217. e6, 2021 | 13 | 2021 |
A long interval between priming and boosting SARS-CoV-2 mRNA vaccine doses enhances B cell responses with limited impact on T cell immunity A Nicolas, G Sannier, M Dubé, M Nayrac, MM Painter, RR Goel, ... bioRxiv, 2022.08. 03.502672, 2022 | 3 | 2022 |
A mouse model of vitiligo with focused epidermal depigmentation requires IFN-γ for autoreactive CD8+ T-cell accumulation in the skin JE Harris, TH Harris, W Weninger, EJ Wherry, CA Hunter, LA Turka Journal of Investigative Dermatology 132 (7), 1869-1876, 2012 | 405 | 2012 |
A new mouse model of vitiligo with epidermal depigmentation reveals a critical role for IFN-gamma in autoreactive T cell homing to the skin JE Harris, TH Harris, W Weninger, EJ Wherry, CA Hunter, LA Turka PIGMENT CELL & MELANOMA RESEARCH 24 (4), 808-808, 2011 | 2 | 2011 |
A phase I trial of pembrolizumab with hypofractionated radiation therapy (HFRT) in patients with metastatic cancers A Maity, R Mick, AC Huang, SM George, MD Farwell, JN Lukens, ... International Journal of Radiation Oncology, Biology, Physics 102 (3), S25, 2018 | 1 | 2018 |
A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours A Maity, R Mick, AC Huang, SM George, MD Farwell, JN Lukens, ... British journal of cancer 119 (10), 1200-1207, 2018 | 98 | 2018 |
A Prognostic Proteomic Signature of Immune Dysregulation Is Present at Onset of Multiple Organ Dysfunction Syndrome in Pediatric Patients With and Without Sepsis RB Lindell, S Sayed, JS Campos, JC Fitzgerald, N Yehya, ST Famularo, ... D28. PEDIATRIC PULMONOLOGY BENCH-TO-BEDSIDE: GENETICS, WHOLE-EXOME …, 2024 | | 2024 |
A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infection A Crawford, JM Angelosanto, KL Nadwodny, SD Blackburn, EJ Wherry PLoS pathogens 7 (7), e1002098, 2011 | 208 | 2011 |
A role for the transcription factor STAT5 in antagonizing CD8+ T cell exhaustion JC Beltra, S Manne, MS Abdel-Hakeem, K Nzingha, Z Zhang, H Huang, ... The Journal of Immunology 206 (1_Supplement), 14.13-14.13, 2021 | | 2021 |
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A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma AC Huang, RJ Orlowski, X Xu, R Mick, SM George, PK Yan, S Manne, ... Nature medicine 25 (3), 454-461, 2019 | 571 | 2019 |