A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection H Liu, M Yuan, D Huang, S Bangaru, F Zhao, CCD Lee, L Peng, ... Cell host & microbe 29 (5), 806-818. e6, 2021 | 56 | 2021 |
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection P Zhou, M Yuan, G Song, N Beutler, N Shaabani, D Huang, W He, X Zhu, ... Science translational medicine 14 (637), eabi9215, 2022 | 136 | 2022 |
A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody NC Wu, M Yuan, S Bangaru, D Huang, X Zhu, CCD Lee, HL Turner, ... PLoS pathogens 16 (12), e1009089, 2020 | 66 | 2020 |
A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies F Ferrara, MF Erasmus, S D’Angelo, C Leal-Lopes, AA Teixeira, ... Nature communications 13 (1), 462, 2022 | 28 | 2022 |
A protective broadly cross-reactive human antibody defines a conserved site of vulnerability on beta-coronavirus spikes P Zhou, M Yuan, G Song, N Beutler, N Shaabani, D Huang, W He, X Zhu, ... | 34 | 2021 |
A rapid assay for SARS-CoV-2 neutralizing antibodies that is insensitive to antiretroviral drugs D Huang, JT Tran, L Peng, L Yang, RT Suhandynata, MA Hoffman, ... The Journal of Immunology 207 (1), 344-351, 2021 | 5 | 2021 |
A role of RIP3-mediated macrophage necrosis in atherosclerosis development J Lin, H Li, M Yang, J Ren, Z Huang, F Han, J Huang, J Ma, D Zhang, ... Cell reports 3 (1), 200-210, 2013 | 301 | 2013 |
An engineered antibody with broad protective efficacy in murine models of SARS and COVID-19 CG Rappazzo, VT Longping, CI Kaku, D Wrapp, M Sakharkar, D Huang, ... BioRxiv, 2020 | 13 | 2020 |
B cell receptor modification in b cells JE Voss, R Andrabi, DR Burton, D Huang, A Gonzalez-Martin US Patent App. 16/642,810, 2023 | | 2023 |
B cells expressing authentic naive human VRC01-class BCRs can be recruited to germinal centers and affinity mature in multiple independent mouse models D Huang, RK Abbott, C Havenar-Daughton, PD Skog, R Al-Kolla, ... Proceedings of the National Academy of Sciences 117 (37), 22920-22931, 2020 | 55 | 2020 |
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern H Cho, KK Gonzales-Wartz, D Huang, M Yuan, M Peterson, J Liang, ... Science translational medicine 13 (616), eabj5413, 2021 | 86 | 2021 |
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody CG Rappazzo, LV Tse, CI Kaku, D Wrapp, M Sakharkar, D Huang, ... Science 371 (6531), 823-829, 2021 | 296 | 2021 |
Broad neutralization of SARS-related viruses by human monoclonal antibodies AZ Wec, D Wrapp, AS Herbert, DP Maurer, D Haslwanter, M Sakharkar, ... Science 369 (6504), 731-736, 2020 | 544 | 2020 |
Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein AZ Wec, D Wrapp, AS Herbert, D Maurer, D Haslwanter, M Sakharkar, ... BioRxiv, 2020 | 26 | 2020 |
Broadening a SARS-CoV-1–neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution F Zhao, M Yuan, C Keating, N Shaabani, O Limbo, C Joyce, J Woehl, ... Science Signaling 16 (798), eabk3516, 2023 | 13 | 2023 |
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques W He, M Yuan, S Callaghan, R Musharrafieh, G Song, M Silva, N Beutler, ... Science translational medicine 14 (657), eabl9605, 2022 | 24 | 2022 |
Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors AL Gavin, D Huang, TR Blane, TC Thinnes, Y Murakami, R Fukui, ... Nature Communications 12 (1), 5874, 2021 | 28 | 2021 |
Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors, including endolysosomal TLRs and a STING dependent sensing pathway. D Nemazee, L Peng, T Blane, D Huang, A Gavin The Journal of Immunology 208 (1_Supplement), 158.05-158.05, 2022 | | 2022 |
Commercial serology assays predict neutralization activity against SARS-CoV-2 RT Suhandynata, MA Hoffman, D Huang, JT Tran, MJ Kelner, SL Reed, ... Clinical Chemistry 67 (2), 404-414, 2021 | 66 | 2021 |
Covid-19 antibodies and uses thereof D Sok, J Jardine, E Landais, D Burton, T Rogers, F Zhao, D Huang US Patent App. 17/923,313, 2023 | | 2023 |