A NEW NON-HUMAN PRIMATE MODEL FOR TESTING HUMAN MALARIA VACCINE EFFICACY MJ Shears, C Parthiban, BC Stone, B Sim, K Lee, SL Hoffman, RA Seder, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 101, 131-131, 2019 | | 2019 |
A TWO DOSE SPOROZOITE CHALLENGE MODEL IN MICE HIGHLIGHTS LIVER STAGE DURATION AS ONE OF THE MOST IMPORTANT DIFFERENCES BETWEEN MURINE AND HUMAN PLASMODIUM FOR VACCINE DEVELOPMENT C Parthiban, ZP Billman, TM Olsen, BC Stone, MJ Shears, SC Murphy AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 101, 321-321, 2019 | | 2019 |
Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine Z MacMillen, K Hatzakis, A Simpson, MJ Shears, F Watson, JH Erasmus, ... npj Vaccines 9 (1), 12, 2024 | 2 | 2024 |
Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites SE Lindner, KE Swearingen, MJ Shears, A Sebastian, MP Walker, ... Nature communications 13 (1), 283, 2022 | 1 | 2022 |
AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes C Marques-da-Silva, B Poudel, RP Baptista, K Peissig, LS Hancox, ... Proceedings of the National Academy of Sciences 120 (2), e2210181120, 2023 | 8 | 2023 |
Alpha-v–containing integrins are host receptors for the Plasmodium falciparum sporozoite surface protein, TRAP K Dundas, MJ Shears, Y Sun, CS Hopp, C Crosnier, T Metcalf, G Girling, ... Proceedings of the National Academy of Sciences 115 (17), 4477-4482, 2018 | 51 | 2018 |
Altered cleavage of Caspase-1 in hepatocytes limits control of malaria in the liver C Marques-da-Silva, B Poudel, RP Baptista, K Peissig, LS Hancox, ... Biorxiv, 2021.01. 28.427517, 2021 | 3 | 2021 |
Apicoplast-Localized Lysophosphatidic Acid Precursor Assembly Is Required for Bulk Phospholipid Synthesis in Toxoplasma gondii and Relies on an Algal/Plant … S Amiar, JI MacRae, DL Callahan, D Dubois, GG van Dooren, MJ Shears, ... PLoS pathogens 12 (8), e1005765, 2016 | 57 | 2016 |
Atypical lipid composition in the purified relict plastid (apicoplast) of malaria parasites CY Botté, Y Yamaryo-Botté, TWT Rupasinghe, KA Mullin, JI MacRae, ... Proceedings of the National Academy of Sciences 110 (18), 7506-7511, 2013 | 139 | 2013 |
Atypical lipid composition in the purified relict plastid (apicoplast) of malaria parasites. Y Yamaryo-Botté, TWT Rupasinghe, KA Mullin, JI Macrae, TP Spurck, ... | | 2013 |
Characterization of the Plasmodium falciparum and P. berghei glycerol 3‐phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite … MJ Shears, JI MacRae, V Mollard, CD Goodman, A Sturm, LM Orchard, ... Cellular microbiology 19 (1), e12633, 2017 | 31 | 2017 |
Cryopreserved sporozoites with and without the glycolipid adjuvant 7DW8-5 protect in prime-and-trap malaria vaccination FN Watson, MJ Shears, J Matsubara, AC Kalata, AM Seilie, IC Talavera, ... The American Journal of Tropical Medicine and Hygiene 106 (4), 1227, 2022 | 11 | 2022 |
Differential sex-specific immune responses following Prime-and-Trap vaccination alters protection against malaria in mice CJ Duncombe, FN Watson, AC Kalata, MJ Shears, SC Murphy The Journal of Immunology 208 (1_Supplement), 181.14-181.14, 2022 | | 2022 |
Direct quantification of single red blood cell hemoglobin concentration with multiphoton microscopy AT Francis, MJ Shears, SC Murphy, D Fu Analytical Chemistry 92 (18), 12235-12241, 2020 | 9 | 2020 |
Division and adaptation to host environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelle remodeling S Amiar, NJ Katris, L Berry, S Dass, S Duley, CS Arnold, MJ Shears, ... Cell Reports 30 (11), 3778-3792. e9, 2020 | 44 | 2020 |
Efficient infection of non-human primates with purified, cryopreserved Plasmodium knowlesi sporozoites S Chakravarty, MJ Shears, ER James, U Rai, N Kc, S Conteh, LE Lambert, ... Malaria Journal 21 (1), 247, 2022 | 7 | 2022 |
EXAMINING QUININE MECHANISM OF ACTION AND RESISTANCE USING A NOVEL PLASMODIUM FALCIPARUM GENETIC CROSS IN HUMANIZED MICE M Kanai, LS Ross, T Yeo, MJ Shears, A Tripathi, S Mok, P Sinnis, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 101, 596-596, 2019 | | 2019 |
EXAMINING THE EPISTATIC INTERACTION BETWEEN PLASMEPSIN II AND PFCRT IN PLASMODIUM. FALCIPARUM PIPERAQUINE RESISTANCE S Mok, L Ross, S Dhingra, T Yeo, M Shears, AK Tripathi, L Musset, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 101, 476-476, 2019 | | 2019 |
EXPERIMENTAL INFECTION OF PIGTAILED MACAQUES WITH PLASMODIUM KNOWLESI MALARIA PARASITES MJ Shears, R Reynolds, S Chakravarty, B Sim, K Lee, SL Hoffman, ... AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 105 (5), 335-335, 2021 | | 2021 |
Exploring how fatty acids synthesized by malaria parasites are incorporated into lipids: Characterization of the Plasmodium apicoplast glycerol-3-phosphate acyltransferase M SHEARS | | 2015 |