The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2 SM Park, AB Gaur, E Lengyel, ME Peter Genes & development 22 (7), 894-907, 2008 | 2728 | 2008 |
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth KM Nieman, HA Kenny, CV Penicka, A Ladanyi, R Buell-Gutbrod, ... Nature medicine 17 (11), 1498-1503, 2011 | 2228 | 2011 |
Ovarian cancer development and metastasis E Lengyel The American journal of pathology 177 (3), 1053-1064, 2010 | 1831 | 2010 |
Whole–genome characterization of chemoresistant ovarian cancer AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ... Nature 521 (7553), 489-494, 2015 | 1506 | 2015 |
Rethinking ovarian cancer: recommendations for improving outcomes S Vaughan, JI Coward, RC Bast Jr, A Berchuck, JS Berek, JD Brenton, ... Nature Reviews Cancer 11 (10), 719-725, 2011 | 1502 | 2011 |
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer DD Bowtell, S Böhm, AA Ahmed, PJ Aspuria, RC Bast Jr, V Beral, ... Nature reviews Cancer 15 (11), 668-679, 2015 | 1163 | 2015 |
Adipose tissue and adipocytes support tumorigenesis and metastasis KM Nieman, IL Romero, B Van Houten, E Lengyel Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013 | 834 | 2013 |
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer J Liu, MA Eckert, BT Harada, SM Liu, Z Lu, K Yu, SM Tienda, ... Nature cell biology 20 (9), 1074-1083, 2018 | 644 | 2018 |
Let-7 expression defines two differentiation stages of cancer S Shell, SM Park, AR Radjabi, R Schickel, EO Kistner, DA Jewell, C Feig, ... Proceedings of the National Academy of Sciences 104 (27), 11400-11405, 2007 | 602 | 2007 |
Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b A Schnelzer, D Prechtel, U Knaus, K Dehne, M Gerhard, H Graeff, ... Oncogene 19 (26), 3013-3020, 2000 | 548 | 2000 |
Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer B Schmalfeldt, D Prechtel, K Härting, K Späthe, S Rutke, E Konik, ... Clinical Cancer Research 7 (8), 2396-2404, 2001 | 497 | 2001 |
CD95 promotes tumour growth L Chen, SM Park, AV Tumanov, A Hau, K Sawada, C Feig, JR Turner, ... Nature 465 (7297), 492-496, 2010 | 458 | 2010 |
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin HA Kenny, S Kaur, LM Coussens, E Lengyel The Journal of clinical investigation 118 (4), 1367-1379, 2008 | 435 | 2008 |
Loss of E-cadherin promotes ovarian cancer metastasis via α5-integrin, which is a therapeutic target K Sawada, AK Mitra, AR Radjabi, V Bhaskar, EO Kistner, M Tretiakova, ... Cancer research 68 (7), 2329-2339, 2008 | 429 | 2008 |
Stimulation of 92-kDa Gelatinase B Promoter Activity by ras Is Mitogen-activated Protein Kinase Kinase 1-independent and Requires Multiple Transcription Factor Binding Sites … R Gum, E Lengyel, J Juarez, JH Chen, H Sato, M Seiki, D Boyd Journal of Biological Chemistry 271 (18), 10672-10680, 1996 | 425 | 1996 |
Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis A Ladanyi, A Mukherjee, HA Kenny, A Johnson, AK Mitra, S Sundaresan, ... Oncogene 37 (17), 2285-2301, 2018 | 418 | 2018 |
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer AK Mitra, M Zillhardt, Y Hua, P Tiwari, AE Murmann, ME Peter, E Lengyel Cancer discovery 2 (12), 1100-1108, 2012 | 398 | 2012 |
Dosimetric predictors of acute hematologic toxicity in cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy LK Mell, JD Kochanski, JC Roeske, JJ Haslam, N Mehta, SD Yamada, ... International Journal of Radiation Oncology* Biology* Physics 66 (5), 1356-1365, 2006 | 384 | 2006 |
Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts MA Eckert, F Coscia, A Chryplewicz, JW Chang, KM Hernandez, S Pan, ... Nature 569 (7758), 723-728, 2019 | 372 | 2019 |
C‐Met overexpression in node‐positive breast cancer identifies patients with poor clinical outcome independent of Her2/neu E Lengyel, D Prechtel, JH Resau, K Gauger, A Welk, K Lindemann, ... International journal of cancer 113 (4), 678-682, 2005 | 352 | 2005 |