| Small molecule drug A-769662 and AMP synergistically activate naive AMPK independent of upstream kinase signaling JW Scott, N Ling, SMA Issa, TA Dite, MT O’Brien, ZP Chen, S Galic, ... Chemistry & biology 21 (5), 619-627, 2014 | 172 | 2014 |
| mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress NXY Ling, A Kaczmarek, A Hoque, E Davie, KRW Ngoei, KR Morrison, ... Nature metabolism 2 (1), 41-49, 2020 | 135 | 2020 |
| AMP-activated protein kinase selectively inhibited by the type II inhibitor SBI-0206965 TA Dite, CG Langendorf, A Hoque, S Galic, RJ Rebello, AJ Ovens, ... Journal of Biological Chemistry 293 (23), 8874-8885, 2018 | 126 | 2018 |
| The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs TA Dite, NXY Ling, JW Scott, A Hoque, S Galic, BL Parker, KRW Ngoei, ... Nature Communications 8 (1), 571, 2017 | 77 | 2017 |
| Inhibition of AMP-activated protein kinase at the allosteric drug-binding site promotes islet insulin release JW Scott, S Galic, KL Graham, R Foitzik, NXY Ling, TA Dite, SMA Issa, ... Chemistry & biology 22 (6), 705-711, 2015 | 61 | 2015 |
| Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone C Vrahnas, M Blank, TA Dite, L Tatarczuch, N Ansari, B Crimeen-Irwin, ... Nature communications 10 (1), 3436, 2019 | 59 | 2019 |
| Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion LM Lindqvist, D Frank, K McArthur, TA Dite, M Lazarou, JS Oakhill, BT Kile, ... Cell Death & Differentiation 25 (4), 784-796, 2018 | 56 | 2018 |
| Structural determinants for small-molecule activation of skeletal muscle AMPK α2β2γ1 by the glucose importagog SC4 KRW Ngoei, CG Langendorf, NXY Ling, A Hoque, S Varghese, ... Cell chemical biology 25 (6), 728-737. e9, 2018 | 51 | 2018 |
| Autophosphorylation of CaMKK2 generates autonomous activity that is disrupted by a T85S mutation linked to anxiety and bipolar disorder JW Scott, E Park, RM Rodriguiz, JS Oakhill, SMA Issa, MT O’Brien, ... Scientific reports 5 (1), 14436, 2015 | 39 | 2015 |
| CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins CG Langendorf, MT O'Brien, KRW Ngoei, LM McAloon, U Dhagat, ... Journal of Biological Chemistry 295 (48), 16239-16250, 2020 | 35 | 2020 |
| Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism NJ Hoffman, J Whitfield, NR Janzen, MR Belhaj, S Galic, L Murray-Segal, ... Molecular Metabolism 41, 101048, 2020 | 29 | 2020 |
| Impact of Genetic Variation on Human CaMKK2 Regulation by Ca2+-Calmodulin and Multisite Phosphorylation MT O’Brien, JS Oakhill, NXY Ling, CG Langendorf, A Hoque, TA Dite, ... Scientific reports 7 (1), 43264, 2017 | 23 | 2017 |
| The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs LY Liang, M Roy, CR Horne, JJ Sandow, M Surudoi, LF Dagley, ... Biochemical Journal 478 (17), 3351-3371, 2021 | 13 | 2021 |
| Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling MJ Roy, MG Surudoi, A Kropp, J Hou, W Dai, JM Hardy, LY Liang, ... Nature Communications 14 (1), 3542, 2023 | 6 | 2023 |
| Transient expression of AMPK heterotrimer complexes in mammalian cells JS Oakhill, JW Scott, TA Dite AMPK: Methods and Protocols, 159-169, 2018 | 5 | 2018 |
| Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization Y Meng, SE Garnish, KA Davies, KA Black, AP Leis, CR Horne, ... Nature Communications 14 (1), 6804, 2023 | 4 | 2023 |
| Author Correction: Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone C Vrahnas, M Blank, TA Dite, L Tatarczuch, N Ansari, B Crimeen-Irwin, ... Nature communications 10 (1), 5073, 2019 | 4 | 2019 |
| Cryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin KTG Sarson-Lawrence, JM Hardy, J Iaria, D Stockwell, K Behrens, ... Nature Communications 15 (1), 1135, 2024 | 2 | 2024 |
| NRPB1 is a WNK-like pseudokinase that modulates the activity of the WNK4-SPAK/OSR1 pathway with implications in the physiology of the distal convoluted tubule GR Magaña-Aviila, H Carbajal-Contreras, R Amnekar, T Dite, N Vazquez, ... Physiology 39 (S1), 1507, 2024 | | 2024 |
| Caspase-2 protects against ferroptotic cell death S Dawar, MC Benitez, Y Lim, TA Dite, JM Yousef, N Thio, S Garciaz, ... Cell Death & Disease 15 (3), 182, 2024 | | 2024 |
