Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13297* | 2021 |
Targeting the pro-death and pro-survival functions of autophagy as novel therapeutic strategies in cancer K Dalby, I Tekedereli, G Lopez-Berestein, B Ozpolat Autophagy 6 (3), 322-329, 2010 | 516 | 2010 |
Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90 rsk that are inducible by MAPK KN Dalby, N Morrice, FB Caudwell, J Avruch, P Cohen Journal of Biological Chemistry 273 (3), 1496-1505, 1998 | 471 | 1998 |
The cyanobacterial toxin microcystin binds covalently to cysteine-273 on protein phosphatase 1 RW MacKintosh, KN Dalby, DG Campbell, PTW Cohen, P Cohen, ... FEBS letters 371 (3), 236-240, 1995 | 376 | 1995 |
Virtual screening using molecular simulations T Yang, JC Wu, C Yan, Y Wang, R Luo, MB Gonzales, KN Dalby, P Ren Proteins: Structure, Function, and Bioinformatics 79 (6), 1940-1951, 2011 | 216 | 2011 |
Construction of human activity‐based phosphorylation networks RH Newman, J Hu, HS Rho, Z Xie, C Woodard, J Neiswinger, C Cooper, ... Molecular systems biology 9 (1), 655, 2013 | 190 | 2013 |
Substrate discrimination among mitogen-activated protein kinases through distinct docking sequence motifs DL Sheridan, Y Kong, SA Parker, KN Dalby, BE Turk Journal of Biological Chemistry 283 (28), 19511-19520, 2008 | 178 | 2008 |
Comparison of the specificities of p70 S6 kinase and MAPKAP kinase‐1 identifies a relatively specific substrate for p70 S6 kinase: the N‐terminal kinase domain of MAPKAP kinase … IA Leighton, KN Dalby, F Barry Caudwell, PTW Cohen, P Cohen FEBS letters 375 (3), 289-293, 1995 | 158 | 1995 |
Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer I Tekedereli, SN Alpay, CDJ Tavares, ZE Cobanoglu, TS Kaoud, I Sahin, ... PloS one 7 (7), e41171, 2012 | 141 | 2012 |
Tinker‐OpenMM: Absolute and relative alchemical free energies using AMOEBA on GPUs M Harger, D Li, Z Wang, K Dalby, L Lagardère, JP Piquemal, J Ponder, ... Journal of computational chemistry 38 (23), 2047-2055, 2017 | 112 | 2017 |
The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation S Coffa, M Breitman, SM Hanson, K Callaway, S Kook, KN Dalby, ... PLoS One 6 (12), e28723, 2011 | 103 | 2011 |
The kinetic mechanism of the dual phosphorylation of the ATF2 transcription factor by p38 mitogen-activated protein (MAP) kinase α: implications for signal/response profiles of … WF Waas, HH Lo, KN Dalby Journal of Biological Chemistry 276 (8), 5676-5684, 2001 | 98 | 2001 |
Modeling organochlorine compounds and the σ-hole effect using a polarizable multipole force field X Mu, Q Wang, LP Wang, SD Fried, JP Piquemal, KN Dalby, P Ren The Journal of Physical Chemistry B 118 (24), 6456-6465, 2014 | 93 | 2014 |
193‐nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization JA Madsen, TS Kaoud, KN Dalby, JS Brodbelt Proteomics 11 (7), 1329-1334, 2011 | 93 | 2011 |
c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun X Xie, TS Kaoud, R Edupuganti, T Zhang, T Kogawa, Y Zhao, ... Oncogene 36 (18), 2599-2608, 2017 | 89 | 2017 |
BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling H Vin, SS Ojeda, G Ching, ML Leung, V Chitsazzadeh, DW Dwyer, ... Elife 2, e00969, 2013 | 86 | 2013 |
MEK inhibitor selumetinib (AZD6244; ARRY-142886) prevents lung metastasis in a triple-negative breast cancer xenograft model C Bartholomeusz, X Xie, MK Pitner, K Kondo, A Dadbin, J Lee, H Saso, ... Molecular cancer therapeutics 14 (12), 2773-2781, 2015 | 81 | 2015 |
Dopamine depletion and subsequent treatment with l‐DOPA, but not the long‐lived dopamine agonist pergolide, enhances activity of the Akt pathway in the rat … E Bychkov, MR Ahmed, KN Dalby, EV Gurevich Journal of neurochemistry 102 (3), 699-711, 2007 | 78 | 2007 |
Nonvisual arrestins function as simple scaffolds assembling the MKK4–JNK3α2 signaling complex X Zhan, TS Kaoud, KN Dalby, VV Gurevich Biochemistry 50 (48), 10520-10529, 2011 | 73 | 2011 |
Synthesis and biological evaluation of pyrido [2, 3-d] pyrimidine-2, 4-dione derivatives as eEF-2K inhibitors R Edupuganti, Q Wang, CDJ Tavares, CA Chitjian, JL Bachman, P Ren, ... Bioorganic & medicinal chemistry 22 (17), 4910-4916, 2014 | 72 | 2014 |