Senescence in premalignant tumours M Collado, J Gil, A Efeyan, C Guerra, AJ Schuhmacher, M Barradas, ... Nature 436 (7051), 642-642, 2005 | 1764 | 2005 |
Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese S Enerbäck, A Jacobsson, EM Simpson, C Guerra, H Yamashita, ... Nature 387 (6628), 90-94, 1997 | 1587 | 1997 |
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice C Guerra, AJ Schuhmacher, M Cañamero, PJ Grippo, L Verdaguer, ... Cancer cell 11 (3), 291-302, 2007 | 1365 | 2007 |
Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. C Guerra, RA Koza, H Yamashita, K Walsh, LP Kozak The Journal of clinical investigation 102 (2), 412-420, 1998 | 772 | 1998 |
Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context C Guerra, N Mijimolle, A Dhawahir, P Dubus, M Barradas, M Serrano, ... Cancer cell 4 (2), 111-120, 2003 | 660 | 2003 |
Pancreatitis-induced inflammation contributes to pancreatic cancer by inhibiting oncogene-induced senescence C Guerra, M Collado, C Navas, AJ Schuhmacher, I Hernández-Porras, ... Cancer cell 19 (6), 728-739, 2011 | 549 | 2011 |
A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma M Puyol, A Martín, P Dubus, F Mulero, P Pizcueta, G Khan, C Guerra, ... Cancer cell 18 (1), 63-73, 2010 | 500 | 2010 |
EGF receptor signaling is essential for k-ras oncogene-driven pancreatic ductal adenocarcinoma C Navas, I Hernández-Porras, AJ Schuhmacher, M Sibilia, C Guerra, ... Cancer cell 22 (3), 318-330, 2012 | 417 | 2012 |
Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors M Murga, S Campaner, AJ Lopez-Contreras, LI Toledo, R Soria, ... Nature structural & molecular biology 18 (12), 1331-1335, 2011 | 412 | 2011 |
p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation JJ Ventura, S Tenbaum, E Perdiguero, M Huth, C Guerra, M Barbacid, ... Nature genetics 39 (6), 750-758, 2007 | 365 | 2007 |
Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival M Drosten, A Dhawahir, EYM Sum, J Urosevic, CG Lechuga, LM Esteban, ... The EMBO journal 29 (6), 1091-1104, 2010 | 349 | 2010 |
Stromal disrupting effects of nab-paclitaxel in pancreatic cancer R Alvarez, M Musteanu, E Garcia-Garcia, PP Lopez-Casas, D Megias, ... British journal of cancer 109 (4), 926-933, 2013 | 308 | 2013 |
Brown adipose tissue–specific insulin receptor knockout shows diabetic phenotype without insulin resistance C Guerra, P Navarro, AM Valverde, M Arribas, J Brüning, LP Kozak, ... The Journal of clinical investigation 108 (8), 1205-1213, 2001 | 277 | 2001 |
Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo OJ Sansom, V Meniel, JA Wilkins, AM Cole, KA Oien, V Marsh, ... Proceedings of the National Academy of Sciences 103 (38), 14122-14127, 2006 | 239 | 2006 |
Genetically engineered mouse models of pancreatic adenocarcinoma C Guerra, M Barbacid Molecular oncology 7 (2), 232-247, 2013 | 203 | 2013 |
What we have learned about pancreatic cancer from mouse models PA Pérez–Mancera, C Guerra, M Barbacid, DA Tuveson Gastroenterology 142 (5), 1079-1092, 2012 | 190 | 2012 |
Upregulation of miR-21 by Ras in vivo and its role in tumor growth D Frezzetti, M De Menna, P Zoppoli, C Guerra, A Ferraro, AM Bello, ... Oncogene 30 (3), 275-286, 2011 | 168 | 2011 |
DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS M Lauth, Å Bergström, T Shimokawa, U Tostar, Q Jin, V Fendrich, ... Nature structural & molecular biology 17 (6), 718-725, 2010 | 168 | 2010 |
Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors M Djurec, O Graña, A Lee, K Troulé, E Espinet, L Cabras, C Navas, ... Proceedings of the National Academy of Sciences 115 (6), E1147-E1156, 2018 | 161 | 2018 |
Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk CA Orozco, N Martinez-Bosch, PE Guerrero, J Vinaixa, T Dalotto-Moreno, ... Proceedings of the National Academy of Sciences 115 (16), E3769-E3778, 2018 | 158 | 2018 |