An atlas of combinatorial transcriptional regulation in mouse and man T Ravasi, H Suzuki, CV Cannistraci Cell 140 (5), 744-752, 2010 | 840 | 2010 |
Decade-long leukaemia remissions with persistence of CD4+ CAR T cells JJ Melenhorst, GM Chen, M Wang, DL Porter, C Chen, MKA Collins, ... Nature 602 (7897), 503-509, 2022 | 534 | 2022 |
The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line Nature genetics 41 (5), 553-562, 2009 | 419 | 2009 |
A lineage-resolved molecular atlas of C. elegans embryogenesis at single-cell resolution JS Packer, Q Zhu, C Huynh, P Sivaramakrishnan, E Preston, H Dueck, ... Science 365 (6459), eaax1971, 2019 | 415 | 2019 |
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 397 | 2020 |
Global view of enhancer–promoter interactome in human cells B He, C Chen, L Teng, K Tan Proceedings of the National Academy of Sciences 111 (21), E2191-E2199, 2014 | 287 | 2014 |
Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production Y Li, V Esain, L Teng, J Xu, W Kwan, IM Frost, AD Yzaguirre, X Cai, ... Genes & development 28 (23), 2597-2612, 2014 | 262 | 2014 |
The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American women MV Dogan, B Shields, C Cutrona, L Gao, FX Gibbons, R Simons, ... BMC genomics 15, 1-13, 2014 | 227 | 2014 |
Runx1 deficiency decreases ribosome biogenesis and confers stress resistance to hematopoietic stem and progenitor cells X Cai, L Gao, L Teng, J Ge, ZM Oo, AR Kumar, DG Gilliland, PJ Mason, ... Cell stem cell 17 (2), 165-177, 2015 | 215 | 2015 |
Discover regulatory DNA elements using chromatin signatures and artificial neural network HA Firpi, D Ucar, K Tan Bioinformatics 26 (13), 1579-1586, 2010 | 189 | 2010 |
H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification D Nicetto, G Donahue, T Jain, T Peng, S Sidoli, L Sheng, T Montavon, ... Science 363 (6424), 294-297, 2019 | 187 | 2019 |
TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4+ T cell fate and interact with Runx3 to silence Cd4 in CD8+ T cells FC Steinke, S Yu, X Zhou, B He, W Yang, B Zhou, H Kawamoto, J Zhu, ... Nature immunology 15 (7), 646-656, 2014 | 177 | 2014 |
EnhancerAtlas: a resource for enhancer annotation and analysis in 105 human cell/tissue types T Gao, B He, S Liu, H Zhu, K Tan, J Qian Bioinformatics 32 (23), 3543-3551, 2016 | 171 | 2016 |
A comparative genomics approach to prediction of new members of regulons K Tan, G Moreno-Hagelsieb, J Collado-Vides, GD Stormo Genome research 11 (4), 566-584, 2001 | 158 | 2001 |
4DGenome: a comprehensive database of chromatin interactions L Teng, B He, J Wang, K Tan Bioinformatics 31 (15), 2560-2564, 2015 | 145 | 2015 |
Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide D Lu, K Fütterer, S Korolev, X Zheng, K Tan, G Waksman, JE Sadler Journal of molecular biology 292 (2), 361-373, 1999 | 136 | 1999 |
Developmental trajectory of prehematopoietic stem cell formation from endothelium Q Zhu, P Gao, J Tober, L Bennett, C Chen, Y Uzun, Y Li, ED Howell, ... Blood, The Journal of the American Society of Hematology 136 (7), 845-856, 2020 | 128 | 2020 |
A microfluidic device for epigenomic profiling using 100 cells Z Cao, C Chen, B He, K Tan, C Lu Nature methods 12 (10), 959-962, 2015 | 127 | 2015 |
Integrative bulk and single-cell profiling of premanufacture T-cell populations reveals factors mediating long-term persistence of CAR T-cell therapy GM Chen, C Chen, RK Das, P Gao, CH Chen, S Bandyopadhyay, ... Cancer Discovery 11 (9), 2186-2199, 2021 | 111 | 2021 |
SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data T Peng, Q Zhu, P Yin, K Tan Genome biology 20, 1-12, 2019 | 105 | 2019 |