In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration K Suzuki, Y Tsunekawa, R Hernandez-Benitez, J Wu, J Zhu, EJ Kim, ... Nature 540 (7631), 144-149, 2016 | 1200 | 2016 |
In vivo amelioration of age-associated hallmarks by partial reprogramming A Ocampo, P Reddy, P Martinez-Redondo, A Platero-Luengo, F Hatanaka, ... Cell 167 (7), 1719-1733. e12, 2016 | 781 | 2016 |
Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse M Mukhopadhyay, S Shtrom, C Rodriguez-Esteban, L Chen, T Tsukui, ... Developmental cell 1 (3), 423-434, 2001 | 768 | 2001 |
Pitx2 determines left–right asymmetry of internal organs in vertebrates AK Ryan, B Blumberg, C Rodriguez-Esteban, S Yonei-Tamura, K Tamura, ... Nature 394 (6693), 545-551, 1998 | 612 | 1998 |
Interspecies chimerism with mammalian pluripotent stem cells J Wu, A Platero-Luengo, M Sakurai, A Sugawara, MA Gil, T Yamauchi, ... Cell 168 (3), 473-486. e15, 2017 | 557 | 2017 |
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging W Zhang, J Li, K Suzuki, J Qu, P Wang, J Zhou, X Liu, R Ren, X Xu, ... Science 348 (6239), 1160-1163, 2015 | 529 | 2015 |
Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud M Kengaku, J Capdevila, C Rodriguez-Esteban, J De La Pena, ... Science 280 (5367), 1274-1277, 1998 | 475 | 1998 |
Role of the Bicoid-related homeodomain factor Pitx1 in specifying hindlimb morphogenesis and pituitary development DP Szeto, C Rodriguez-Esteban, AK Ryan, SM O’Connell, F Liu, ... Genes & development 13 (4), 484-494, 1999 | 470 | 1999 |
In vivo target gene activation via CRISPR/Cas9-mediated trans-epigenetic modulation HK Liao, F Hatanaka, T Araoka, P Reddy, MZ Wu, Y Sui, T Yamauchi, ... Cell 171 (7), 1495-1507. e15, 2017 | 438 | 2017 |
WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo Y Kawakami, J Capdevila, D Büscher, T Itoh, CR Esteban, JCI Belmonte Cell 104 (6), 891-900, 2001 | 428 | 2001 |
Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells HK Liao, Y Gu, A Diaz, J Marlett, Y Takahashi, M Li, K Suzuki, R Xu, ... Nature communications 6 (1), 6413, 2015 | 412 | 2015 |
Progressive degeneration of human neural stem cells caused by pathogenic LRRK2 GH Liu, J Qu, K Suzuki, E Nivet, M Li, N Montserrat, F Yi, X Xu, S Ruiz, ... Nature 491 (7425), 603-607, 2012 | 402 | 2012 |
Activation of Notch signaling pathway precedes heart regeneration in zebrafish A Raya, CM Koth, D Büscher, Y Kawakami, T Itoh, RM Raya, G Sternik, ... Proceedings of the National Academy of Sciences 100 (suppl_1), 11889-11895, 2003 | 390 | 2003 |
Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells Y Xia, E Nivet, I Sancho-Martinez, T Gallegos, K Suzuki, D Okamura, ... Nature cell biology 15 (12), 1507-1515, 2013 | 380 | 2013 |
Wnt/β-catenin signaling regulates vertebrate limb regeneration Y Kawakami, CR Esteban, M Raya, H Kawakami, M Martí, I Dubova, ... Genes & development 20 (23), 3232-3237, 2006 | 377 | 2006 |
Single-cell transcriptomic atlas of primate ovarian aging S Wang, Y Zheng, J Li, Y Yu, W Zhang, M Song, Z Liu, Z Min, H Hu, Y Jing, ... Cell 180 (3), 585-600. e19, 2020 | 374 | 2020 |
Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin J Capdevila, T Tsukui, CR Esteban, V Zappavigna, JCI Belmonte Molecular cell 4 (5), 839-849, 1999 | 363 | 1999 |
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells A Suzuki, Á Raya, Y Kawakami, M Morita, T Matsui, K Nakashima, ... Proceedings of the National Academy of Sciences 103 (27), 10294-10299, 2006 | 347 | 2006 |
The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity C Rodriguez-Esteban, T Tsukui, S Yonei, J Magallon, K Tamura, ... Nature 398 (6730), 814-818, 1999 | 336 | 1999 |
Retinoic acid signalling links left–right asymmetric patterning and bilaterally symmetric somitogenesis in the zebrafish embryo Y Kawakami, Á Raya, RM Raya, C Rodríguez-Esteban, JCI Belmonte Nature 435 (7039), 165-171, 2005 | 316 | 2005 |