Membrane cholesterol dynamics: cholesterol domains and kinetic pools F Schroeder, JR Jefferson, AB Kier, J Knittel, TJ Scallen, WG Wood, ... Proceedings of the Society for Experimental Biology and Medicine 196 (3 …, 1991 | 355 | 1991 |
The Melanocortin 1 Receptor and the UV Response of Human Melanocytes—A Shift in Paradigm† ZA Abdel‐Malek, J Knittel, AL Kadekaro, VB Swope, R Starner Photochemistry and photobiology 84 (2), 501-508, 2008 | 157 | 2008 |
α‐MSH tripeptide analogs activate the melanocortin 1 receptor and reduce UV‐induced DNA damage in human melanocytes ZA Abdel‐Malek, A Ruwe, R Kavanagh‐Starner, AL Kadekaro, V Swope, ... Pigment cell & melanoma research 22 (5), 635-644, 2009 | 110 | 2009 |
Melanoma prevention strategy based on using tetrapeptide α‐MSH analogs that protect human melanocytes from UV‐induced DNA damage and cytotoxicity ZA Abdel-Malek, AL Kadekaro, RJ Kavanagh, A Todorovic, LN Koikov, ... The FASEB journal 20 (9), 1561-1563, 2006 | 102 | 2006 |
Cyclic melanotropins. 9. 7-D-Phenylalanine analogues of the active-site sequence WL Cody, M Mahoney, JJ Knittel, VJ Hruby, AML Castrucci, ME Hadley Journal of medicinal chemistry 28 (5), 583-588, 1985 | 82 | 1985 |
Neuropeptide Y (NPY) Y4 Receptor Selective Agonists Based on NPY(32−36): Development of an Anorectic Y4 Receptor Selective Agonist with Picomolar Affinity A Balasubramaniam, DE Mullins, S Lin, W Zhai, Z Tao, VC Dhawan, ... Journal of medicinal chemistry 49 (8), 2661-2665, 2006 | 77 | 2006 |
Structure-activity studies of highly potent cyclic [Cys4, Cys10] melanotropin analogs JJ Knittel, TK Sawyer, VJ Hruby, ME Hadley Journal of Medicinal Chemistry 26 (2), 125-129, 1983 | 69 | 1983 |
Sub-nanomolar hMC1R agonists by end-capping of the melanocortin tetrapeptide His-D-Phe-Arg-Trp-NH2 LN Koikov, FH Ebetino, MG Solinsky, D Cross-Doersen, JJ Knittel Bioorganic & medicinal chemistry letters 13 (16), 2647-2650, 2003 | 54 | 2003 |
Synthesis and biological actions of highly potent and prolonged acting biotin-labeled melanotropins DN Chaturvedi, JJ Knittel, VJ Hruby, AML Castrucci, ME Hadley Journal of medicinal chemistry 27 (11), 1406-1410, 1984 | 47 | 1984 |
The conformational analysis of aromatic methoxyl groups from carbon-13 chemical shifts and spin-lattice relaxation times A Makriyannis, JJ Knittel Tetrahedron Letters 20 (30), 2753-2756, 1979 | 44 | 1979 |
Development and use of hydrophobic surface area (hsa) descriptors for computer-assisted quantitative structure− activity and structure− property relationship studies DT Stanton, BE Mattioni, JJ Knittel, PC Jurs Journal of chemical information and computer sciences 44 (3), 1010-1023, 2004 | 43 | 2004 |
Modulation of insulin release by adenosine A1 receptor agonists and antagonists in INS‐1 cells: The possible contribution of 86Rb+ efflux and 45Ca2+ uptake M Töpfer, CE Burbiel, CE Müller, J Knittel, EJ Verspohl Cell Biochemistry and Function: Cellular biochemistry and its modulation by …, 2008 | 42 | 2008 |
Conformational and dynamic considerations in the design of peptide hormone analogs VJ Hruby, HI Mosberg, TK Sawyer, JJ Knittel, TW Rockway, J Ormberg, ... Biopolymers: Original Research on Biomolecules 22 (1), 517-530, 1983 | 33 | 1983 |
Structural and conformational modifications of α-MSH/ACTH4–10 provide melanotropin analogues with highly potent behavioral activities MD Hirsch, TL O'Donohue, R Wilson, TK Sawyer, VJ Hruby, ME Hadley, ... Peptides 5 (6), 1197-1201, 1984 | 31 | 1984 |
Studies on phenethylamine hallucinogens. 2. Conformations of arylmethoxyl groups by carbon-13 NMR JJ Knittel, A Makriyannis Journal of Medicinal Chemistry 24 (7), 906-909, 1981 | 31 | 1981 |
Analogs of sub-nanomolar hMC1R agonist LK-184 [Ph (CH2) 3CO-His-D-Phe-Arg-Trp-NH2]. An additional binding site within the human melanocortin receptor 1? LN Koikov, FH Ebetino, MG Solinsky, D Cross-Doersen, JJ Knittel Bioorganic & Medicinal Chemistry Letters 14 (15), 3997-4000, 2004 | 30 | 2004 |
Mechanistic studies of sterol carrier protein-2 effects on L-cell fibroblast plasma membrane sterol domains JK Woodford, I Hapala, JR Jefferson, JJ Knittel, J Kavecansky, D Powell, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1189 (1), 52-60, 1994 | 24 | 1994 |
Drug design and relationship of functional groups to pharmacologic activity JJ Knittel, RM Zavod Foye’s principles of medicinal chemistry. New York, NY: Lippincott Williams …, 2008 | 18 | 2008 |
End-capping of the modified melanocortin tetrapeptide (p-Cl) Phe-D-Phe-Arg-Trp-NH2 as a route to hMC4R agonists LN Koikov, FH Ebetino, JC Hayes, D Cross-Doersen, JJ Knittel Bioorganic & medicinal chemistry letters 14 (19), 4839-4842, 2004 | 18 | 2004 |
Pancreastatin inhibits insulin secretion in RINm5F cells through obstruction of G-protein mediated, calcium-directed exocytosis ZI Hertelendy, DG Patel, JJ Knittel Cell Calcium 19 (2), 125-132, 1996 | 18 | 1996 |