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Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes RJ Strawbridge, J Dupuis, I Prokopenko, A Barker, E Ahlqvist, D Rybin, ... Diabetes 60 (10), 2624-2634, 2011 | 461 | 2011 |
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ... Nature genetics 47 (12), 1415-1425, 2015 | 444* | 2015 |
Control for population structure and relatedness for binary traits in genetic association studies via logistic mixed models H Chen, C Wang, MP Conomos, AM Stilp, Z Li, T Sofer, AA Szpiro, ... The American Journal of Human Genetics 98 (4), 653-666, 2016 | 419 | 2016 |
Genetic association testing using the GENESIS R/Bioconductor package SM Gogarten, T Sofer, H Chen, C Yu, JA Brody, TA Thornton, KM Rice, ... Bioinformatics 35 (24), 5346-5348, 2019 | 315 | 2019 |
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci C Liu, AT Kraja, JA Smith, JA Brody, N Franceschini, JC Bis, K Rice, ... Nature genetics 48 (10), 1162-1170, 2016 | 279* | 2016 |
Sequence kernel association test for quantitative traits in family samples H Chen, JB Meigs, J Dupuis Genetic epidemiology 37 (2), 196-204, 2013 | 246 | 2013 |
A method of moments estimator for random effect multivariate meta-analysis H Chen, AK Manning, J Dupuis Biometrics 68 (4), 1278-1284, 2012 | 215 | 2012 |
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies R Joehanes, X Zhang, T Huan, C Yao, S Ying, QT Nguyen, CY Demirkale, ... Genome biology 18, 1-24, 2017 | 180 | 2017 |
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale X Li, Z Li, H Zhou, SM Gaynor, Y Liu, H Chen, R Sun, R Dey, DK Arnett, ... Nature genetics 52 (9), 969-983, 2020 | 175 | 2020 |
Genetic associations with obstructive sleep apnea traits in Hispanic/Latino Americans BE Cade, H Chen, AM Stilp, KJ Gleason, T Sofer, S Ancoli-Israel, R Arens, ... American journal of respiratory and critical care medicine 194 (7), 886-897, 2016 | 132 | 2016 |
Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole-genome sequencing studies H Chen, JE Huffman, JA Brody, C Wang, S Lee, Z Li, SM Gogarten, ... The American Journal of Human Genetics 104 (2), 260-274, 2019 | 128 | 2019 |
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Test for rare variants by environment interactions in sequencing association studies X Lin, S Lee, MC Wu, C Wang, H Chen, Z Li, X Lin Biometrics 72 (1), 156-164, 2016 | 94 | 2016 |
Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci GA Walford, S Gustafsson, D Rybin, A Stančáková, H Chen, CT Liu, ... Diabetes 65 (10), 3200-3211, 2016 | 90 | 2016 |