| A detailed mammosphere assay protocol for the quantification of breast stem cell activity FL Shaw, H Harrison, K Spence, MP Ablett, BM Simões, G Farnie, ... Journal of mammary gland biology and neoplasia 17, 111-117, 2012 | 438 | 2012 |
| Sox2 promotes tamoxifen resistance in breast cancer cells M Piva, G Domenici, O Iriondo, M Rábano, BM Simões, V Comaills, ... EMBO molecular medicine 6 (1), 66-79, 2014 | 344 | 2014 |
| Recent advances reveal IL-8 signaling as a potential key to targeting breast cancer stem cells JK Singh, BM Simões, SJ Howell, G Farnie, RB Clarke Breast Cancer Research 15, 1-9, 2013 | 283 | 2013 |
| Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and-independent mechanisms JK Singh, G Farnie, NJ Bundred, BM Simões, A Shergill, G Landberg, ... Clinical cancer research 19 (3), 643-656, 2013 | 244 | 2013 |
| Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity BM Simoes, CS O’Brien, R Eyre, A Silva, L Yu, A Sarmiento-Castro, ... Cell reports 12 (12), 1968-1977, 2015 | 194 | 2015 |
| Effects of estrogen on the proportion of stem cells in the breast BM Simões, M Piva, O Iriondo, V Comaills, JA López-Ruiz, I Zabalza, ... Breast cancer research and treatment 129, 23-35, 2011 | 142 | 2011 |
| A Sox2–Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells G Domenici, I Aurrekoetxea-Rodríguez, BM Simões, M Rábano, SY Lee, ... Oncogene 38 (17), 3151-3169, 2019 | 136 | 2019 |
| Multifunctionalized iron oxide nanoparticles for selective drug delivery to CD44-positive cancer cells A Aires, SM Ocampo, BM Simões, MJ Rodríguez, JF Cadenas, ... Nanotechnology 27 (6), 065103, 2016 | 128 | 2016 |
| Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling R Eyre, DG Alférez, A Santiago-Gómez, K Spence, JC McConnell, C Hart, ... Nature communications 10 (1), 5016, 2019 | 124 | 2019 |
| Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling H Harrison, BM Simões, L Rogerson, SJ Howell, G Landberg, RB Clarke Breast Cancer Research 15, 1-12, 2013 | 109 | 2013 |
| Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity C Giordano, F Chemi, S Panza, I Barone, D Bonofiglio, M Lanzino, ... Oncotarget 7 (2), 1262, 2016 | 85 | 2016 |
| A role for notch signalling in breast cancer and endocrine resistance A Acar, BM Simões, RB Clarke, K Brennan Stem cells international 2016 (1), 2498764, 2016 | 81 | 2016 |
| Reprogramming of amino acid transporters to support aspartate and glutamate dependency sustains endocrine resistance in breast cancer M Bacci, N Lorito, L Ippolito, M Ramazzotti, S Luti, S Romagnoli, M Parri, ... Cell reports 28 (1), 104-118. e8, 2019 | 80 | 2019 |
| Cisplatin selects for stem-like cells in osteosarcoma by activating Notch signaling L Yu, Z Fan, S Fang, J Yang, T Gao, BM Simões, R Eyre, W Guo, ... oncotarget 7 (22), 33055, 2016 | 77 | 2016 |
| FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4 L McClements, S Annett, A Yakkundi, M O’Rourke, A Valentine, ... BMC cancer 19, 1-14, 2019 | 55 | 2019 |
| Patient-derived mammosphere and xenograft tumour initiation correlates with progression to metastasis R Eyre, DG Alférez, K Spence, M Kamal, FL Shaw, BM Simões, ... Journal of mammary gland biology and neoplasia 21, 99-109, 2016 | 51 | 2016 |
| The role of steroid hormones in breast cancer stem cells BM Simoes, DG Alferez, SJ Howell, RB Clarke Endocrine-related cancer 22 (6), T177-T186, 2015 | 49 | 2015 |
| Targeting IL-8 signalling to inhibit breast cancer stem cell activity JK Singh, BM Simoes, RB Clarke, NJ Bundred Expert Opinion on Therapeutic Targets 17 (11), 1235-1241, 2013 | 47 | 2013 |
| The role of steroid hormones in breast and effects on cancer stem cells DG Alferez, BM Simões, SJ Howell, RB Clarke Current stem cell reports 4, 81-94, 2018 | 46 | 2018 |
| Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors K Bach, S Pensa, M Zarocsinceva, K Kania, J Stockis, S Pinaud, ... Nature communications 12 (1), 1502, 2021 | 45 | 2021 |
Robert B ClarkeProfessor of Breast Biology, University of Manchester在 manchester.ac.uk 的电子邮件经过验证
