| Origin and health impacts of emissions of toxic by-products and fine particles from combustion and thermal treatment of hazardous wastes and materials SA Cormier, S Lomnicki, W Backes, B Dellinger Environmental Health Perspectives 114 (6), 810-817, 2006 | 277 | 2006 |
| Organization of multiple cytochrome P450s with NADPH-cytochrome P450 reductase in membranes WL Backes, RW Kelley Pharmacology & therapeutics 98 (2), 221-233, 2003 | 189 | 2003 |
| Formation of P450· P450 complexes and their effect on P450 function JR Reed, WL Backes Pharmacology & therapeutics 133 (3), 299-310, 2012 | 112 | 2012 |
| Interactions among P450 enzymes when combined in reconstituted systems: formation of a 2B4− 1A2 complex with a high affinity for NADPH− cytochrome P450 reductase WL Backes, CJ Batie, GF Cawley Biochemistry 37 (37), 12852-12859, 1998 | 101 | 1998 |
| Substrate-dependent competition of different P 450 isoenzymes for limiting NADPH-cytochrome P 450 reductase GF Cawley, CJ Batie, WL Backes Biochemistry 34 (4), 1244-1247, 1995 | 88 | 1995 |
| Cytochrome P-450 LM2 reduction: substrate effects on the rate of reductase-LM2 association WL Backes, CS Eyer Journal of Biological Chemistry 264 (11), 6252-6259, 1989 | 79 | 1989 |
| Ethylbenzene induces microsomal oxygen free radical generation: antibody-directed characterization of the responsible cytochrome P450 enzymes SC Serron, N Dwivedi, WL Backes Toxicology and applied pharmacology 164 (3), 305-311, 2000 | 74 | 2000 |
| Particulate matter containing environmentally persistent free radicals induces AhR-dependent cytokine and reactive oxygen species production in human bronchial epithelial cells AC Harmon, VY Hebert, SA Cormier, B Subramanian, JR Reed, ... PloS one 13 (10), e0205412, 2018 | 65 | 2018 |
| Evidence supporting the interaction of CYP2B4 and CYP1A2 in microsomal preparations GF Cawley, S Zhang, RW Kelley, WL Backes Drug metabolism and disposition 29 (12), 1529-1534, 2001 | 65 | 2001 |
| Cytochrome P450 organization and function are modulated by endoplasmic reticulum phospholipid heterogeneity LM Brignac-Huber, JW Park, JR Reed, WL Backes Drug Metabolism and Disposition 44 (12), 1859-1866, 2016 | 56 | 2016 |
| Effects of ionic strength on the functional interactions between CYP2B4 and CYP1A2 RW Kelley, JR Reed, WL Backes Biochemistry 44 (7), 2632-2641, 2005 | 56 | 2005 |
| Reduction kinetics of purified rat liver cytochrome P-450. Evidence for a sequential reaction mechanism dependent on the hemoprotein spin state PP Tamburini, GG Gibson, WL Backes, SG Sligar, JB Schenkman Biochemistry 23 (20), 4526-4533, 1984 | 56 | 1984 |
| Kinetics of hepatic cytochrome P-450 reduction: correlation with spin state of the ferric heme WL Backes, SG Sligar, JB Schenkman Biochemistry 21 (6), 1324-1330, 1982 | 55 | 1982 |
| Cytochrome P450 system proteins reside in different regions of the endoplasmic reticulum JW Park, JR Reed, LM Brignac-Huber, WL Backes Biochemical Journal 464 (2), 241-249, 2014 | 54 | 2014 |
| Inhibition of cytochrome P450 1A2-mediated metabolism and production of reactive oxygen species by heme oxygenase-1 in rat liver microsomes J R Reed, G F Cawley, W L Backes Drug metabolism letters 5 (1), 6-16, 2011 | 53 | 2011 |
| The role of protein-protein and protein-membrane interactions on P450 function EE Scott, CR Wolf, M Otyepka, SC Humphreys, JR Reed, CJ Henderson, ... Drug Metabolism and Disposition 44 (4), 576-590, 2016 | 52 | 2016 |
| Relationship between the rate of reductase-cytochrome P450 complex formation and the rate of first electron transfer CS Eyer, WL Backes Archives of biochemistry and biophysics 293 (2), 231-240, 1992 | 52 | 1992 |
| Kinetics of cytochrome P-450 reduction: evidence for faster reduction of the high-spin ferric state WL Backes, PP Tamburini, I Jansson, GG Gibson, SG Sligar, ... Biochemistry 24 (19), 5130-5136, 1985 | 49 | 1985 |
| Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions RW Kelley, D Cheng, WL Backes Biochemistry 45 (51), 15807-15816, 2006 | 48 | 2006 |
| Functional interactions between cytochromes P450 1A2 and 2B4 require both enzymes to reside in the same phospholipid vesicle: evidence for physical complex formation JR Reed, M Eyer, WL Backes Journal of Biological Chemistry 285 (12), 8942-8952, 2010 | 47 | 2010 |
