Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress A Wilmes, A Limonciel, L Aschauer, K Moenks, C Bielow, MO Leonard, ... Journal of proteomics 79, 180-194, 2013 | 195 | 2013 |
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics A Wilmes, C Bielow, C Ranninger, P Bellwon, L Aschauer, A Limonciel, ... Toxicology in Vitro 30 (1), 117-127, 2015 | 141 | 2015 |
Expression of xenobiotic transporters in the human renal proximal tubule cell line RPTEC/TERT1 L Aschauer, G Carta, N Vogelsang, E Schlatter, P Jennings Toxicology in Vitro 30 (1), 95-105, 2015 | 97 | 2015 |
Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes A Limonciel, L Aschauer, A Wilmes, S Prajczer, MO Leonard, W Pfaller, ... Toxicology in Vitro 25 (8), 1855-1862, 2011 | 94 | 2011 |
Delineation of the key aspects in the regulation of epithelial monolayer formation L Aschauer, LN Gruber, W Pfaller, A Limonciel, TJ Athersuch, R Cavill, ... Molecular and cellular biology 33 (13), 2535-2550, 2013 | 92 | 2013 |
Novel targets and interaction partners of mutant p53 Gain-Of-Function L Aschauer, PAJ Muller Biochemical Society Transactions 44 (2), 460-466, 2016 | 71 | 2016 |
Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: a transcriptomic study L Aschauer, A Limonciel, A Wilmes, S Stanzel, A Kopp-Schneider, ... Toxicology in Vitro 30 (1), 106-116, 2015 | 68 | 2015 |
Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model P Jennings, C Weiland, A Limonciel, KM Bloch, R Radford, L Aschauer, ... Archives of toxicology 86, 571-589, 2012 | 56 | 2012 |
Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells A Limonciel, A Wilmes, L Aschauer, R Radford, KM Bloch, T McMorrow, ... Archives of toxicology 86, 1741-1751, 2012 | 53 | 2012 |
Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing D Crean, P Bellwon, L Aschauer, A Limonciel, K Moenks, P Hewitt, ... Toxicology in Vitro 30 (1), 128-137, 2015 | 44 | 2015 |
Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing A Limonciel, K Moenks, S Stanzel, GL Truisi, C Parmentier, L Aschauer, ... Toxicology in Vitro 30 (1), 7-18, 2015 | 38 | 2015 |
Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel A Wilmes, L Aschauer, A Limonciel, W Pfaller, P Jennings Toxicology and applied pharmacology 279 (2), 163-172, 2014 | 38 | 2014 |
Interleukin-19 as a translational indicator of renal injury P Jennings, D Crean, L Aschauer, A Limonciel, K Moenks, G Kern, ... Archives of toxicology 89, 101-106, 2015 | 31 | 2015 |
Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane V Phatak, Y von Grabowiecki, J Janus, L Officer, C Behan, L Aschauer, ... Cell death & disease 12 (2), 207, 2021 | 18 | 2021 |
Persistence of epigenomic effects after recovery from repeated treatment with two nephrocarcinogens A Limonciel, SG Van Breda, X Jiang, GD Tredwell, A Wilmes, L Aschauer, ... Frontiers in Genetics 9, 558, 2018 | 8 | 2018 |
Transcriptomic alterations induced by Monuron in rat and human renal proximal tubule cells in vitro and comparison to rat renal-cortex in vivo KM Bloch, N Yaqoob, S Sharma, A Evans, L Aschauer, R Radford, ... Toxicology Research 4 (2), 423-431, 2015 | 6 | 2015 |
Rab11-FIP1/RCP functions as a major signalling hub in the oncogenic roles of mutant p53 in cancer Y von Grabowiecki, V Phatak, L Aschauer, PAJ Muller Frontiers in oncology 11, 804107, 2021 | 5 | 2021 |
Renal cell culture P Jennings, L Aschauer, A Wilmes, G Gstraunthaler In Vitro Toxicology Systems, 79-101, 2014 | 5 | 2014 |
Application of a human renal proximal tubule cell line, RPTEC/TERT1, for chemical safety assessment L Aschauer, A Wilmes, A Limonciel, MO Leonard, W Pfaller, P Jennings Toxicology Letters, S242-S243, 2014 | 2 | 2014 |
Toxicity profiling of nephrotoxins in the human proximal tubular RPTEC-TERT1 cell line: influence of hypoxia D Crean, L Aschauer, P Jennings, M Leonard Altex 27 (suppl 2/10), 31, 2010 | 1 | 2010 |