An integrated encyclopedia of DNA elements in the human genome ENCODE Project Consortium Nature 489 (7414), 57, 2012 | 14003 | 2012 |
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Management Group Liefer Laura A. 51 Wetterstrand Kris A. 51 Good Peter J. 51 ... nature 447 (7146), 799-816, 2007 | 6028 | 2007 |
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome ND Heintzman, RK Stuart, G Hon, Y Fu, CW Ching, RD Hawkins, ... Nature genetics 39 (3), 311-318, 2007 | 3939 | 2007 |
The ENCODE (ENCyclopedia of DNA elements) project EA Feingold, PJ Good, MS Guyer, S Kamholz, L Liefer, K Wetterstrand, ... Science 306 (5696), 636-640, 2004 | 2378 | 2004 |
The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases S Krasemann, C Madore, R Cialic, C Baufeld, N Calcagno, R El Fatimy, ... Immunity 47 (3), 566-581. e9, 2017 | 2051 | 2017 |
High-resolution mapping and characterization of open chromatin across the genome AP Boyle, S Davis, HP Shulha, P Meltzer, EH Margulies, Z Weng, ... Cell 132 (2), 311-322, 2008 | 1723 | 2008 |
ZDOCK: an initial‐stage protein‐docking algorithm R Chen, L Li, Z Weng Proteins: Structure, Function, and Bioinformatics 52 (1), 80-87, 2003 | 1639 | 2003 |
Assessing computational tools for the discovery of transcription factor binding sites M Tompa, N Li, TL Bailey, GM Church, B De Moor, E Eskin, AV Favorov, ... Nature biotechnology 23 (1), 137-144, 2005 | 1591 | 2005 |
ZDOCK server: interactive docking prediction of protein–protein complexes and symmetric multimers BG Pierce, K Wiehe, H Hwang, BH Kim, T Vreven, Z Weng Bioinformatics 30 (12), 1771-1773, 2014 | 1556 | 2014 |
A global map of p53 transcription-factor binding sites in the human genome CL Wei, Q Wu, VB Vega, KP Chiu, P Ng, T Zhang, A Shahab, HC Yong, ... Cell 124 (1), 207-219, 2006 | 1448 | 2006 |
Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals BR Carone, L Fauquier, N Habib, JM Shea, CE Hart, R Li, C Bock, C Li, ... Cell 143 (7), 1084-1096, 2010 | 1261 | 2010 |
Expanded encyclopaedias of DNA elements in the human and mouse genomes JE Moore, MJ Purcaro, HE Pratt, CB Epstein, N Shoresh, J Adrian, T Kawli, ... Nature 583 (7818), 699-710, 2020 | 1229 | 2020 |
Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors J Wang, J Zhuang, S Iyer, XY Lin, TW Whitfield, MC Greven, BG Pierce, ... Genome research 22 (9), 1798-1812, 2012 | 1054 | 2012 |
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo H Yin, CQ Song, JR Dorkin, LJ Zhu, Y Li, Q Wu, A Park, J Yang, S Suresh, ... Nature biotechnology 34 (3), 328-333, 2016 | 946 | 2016 |
Defining functional DNA elements in the human genome M Kellis, B Wold, MP Snyder, BE Bernstein, A Kundaje, GK Marinov, ... Proceedings of the National Academy of Sciences 111 (17), 6131-6138, 2014 | 874 | 2014 |
Comprehensive functional genomic resource and integrative model for the human brain D Wang, S Liu, J Warrell, H Won, X Shi, FCP Navarro, D Clarke, M Gu, ... Science 362 (6420), eaat8464, 2018 | 823 | 2018 |
Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells M Ghildiyal, H Seitz, MD Horwich, C Li, T Du, S Lee, J Xu, ELW Kittler, ... Science 320 (5879), 1077-1081, 2008 | 803 | 2008 |
Unsupervised pattern discovery in human chromatin structure through genomic segmentation MM Hoffman, OJ Buske, J Wang, Z Weng, JA Bilmes, WS Noble Nature methods 9 (5), 473-476, 2012 | 722 | 2012 |
Target RNA–directed trimming and tailing of small silencing RNAs SL Ameres, MD Horwich, JH Hung, J Xu, M Ghildiyal, Z Weng, PD Zamore Science 328 (5985), 1534-1539, 2010 | 699 | 2010 |
Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour AJ Filiano, Y Xu, NJ Tustison, RL Marsh, W Baker, I Smirnov, CC Overall, ... Nature 535 (7612), 425-429, 2016 | 656 | 2016 |