关注
Christopher D. Lima, PhD
Christopher D. Lima, PhD
Chair, Structural Biology Program, Professor and Member, Sloan Kettering Institute, HHMI
在 mskcc.org 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
JR Gareau, CD Lima
Nature reviews Molecular cell biology 11 (12), 861-871, 2010
12882010
Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast
E Mossessova, CD Lima
Molecular cell 5 (5), 865-876, 2000
8672000
Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1
V Bernier-Villamor, DA Sampson, MJ Matunis, CD Lima
Cell 108 (3), 345-356, 2002
7232002
Reconstitution, activities, and structure of the eukaryotic RNA exosome
Q Liu, JC Greimann, CD Lima
Cell 127 (6), 1223-1237, 2006
6802006
Insights into E3 ligase activity revealed by a SUMO–RanGAP1–Ubc9–Nup358 complex
D Reverter, CD Lima
Nature 435 (7042), 687-692, 2005
5662005
Ubiquitin-like protein conjugation: structures, chemistry, and mechanism
L Cappadocia, CD Lima
Chemical reviews 118 (3), 889-918, 2018
5432018
Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein
R Bryk, CD Lima, H Erdjument-Bromage, P Tempst, C Nathan
Science 295 (5557), 1073-1077, 2002
4982002
Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I
CD Lima, JC Wang, A Mondragón
Nature 367 (6459), 138-146, 1994
3871994
Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1
LM Lois, CD Lima
The EMBO journal 24 (3), 439-451, 2005
3682005
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates
U Basu, FL Meng, C Keim, V Grinstein, E Pefanis, J Eccleston, T Zhang, ...
Cell 144 (3), 353-363, 2011
3642011
Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II
C Fabrega, V Shen, S Shuman, CD Lima
Molecular cell 11 (6), 1549-1561, 2003
2882003
Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors
JC Zinder, CD Lima
Genes & development 31 (2), 88-100, 2017
2532017
Active site remodelling accompanies thioester bond formation in the SUMO E1
SK Olsen, AD Capili, X Lu, DS Tan, CD Lima
Nature 463 (7283), 906-912, 2010
2472010
A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex
D Reverter, CD Lima
Structure 12 (8), 1519-1531, 2004
2462004
Small ubiquitin-like modifier modulates abscisic acid signaling in Arabidopsis
LM Lois, CD Lima, NH Chua
The Plant Cell 15 (6), 1347-1359, 2003
2462003
Structure-based analysis of catalysis and substrate definition in the HIT protein family
CD Lima, MG Klein, WA Hendrickson
Science 278 (5336), 286-290, 1997
2451997
Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins
J Hemelaar, A Borodovsky, BM Kessler, D Reverter, J Cook, N Kolli, ...
Molecular and cellular biology 24 (1), 84-95, 2004
2432004
The eukaryotic RNA exosome
K Januszyk, CD Lima
Current opinion in structural biology 24, 132-140, 2014
2312014
MicroRNA biogenesis via splicing and exosome-mediated trimming in Drosophila
AS Flynt, JC Greimann, WJ Chung, CD Lima, EC Lai
Molecular cell 38 (6), 900-907, 2010
2212010
Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway
AA Yunus, CD Lima
Nature structural & molecular biology 13 (6), 491-499, 2006
2212006
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