Substituted thiazoles V. Synthesis and antitumor activity of novel thiazolo [2, 3-b] quinazoline and pyrido [4, 3-d] thiazolo [3, 2-a] pyrimidine analogues FAM Al-Omary, GS Hassan, SM El-Messery, HI El-Subbagh European journal of medicinal chemistry 47, 65-72, 2012 | 133 | 2012 |
Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC … WM Eldehna, MF Abo-Ashour, A Nocentini, RS El-Haggar, S Bua, ... European journal of medicinal chemistry 162, 147-160, 2019 | 90 | 2019 |
Substituted thiazoles VII. Synthesis and antitumor activity of certain 2-(substituted amino)-4-phenyl-1, 3-thiazole analogs GS Hassan, SM El-Messery, FAM Al-Omary, HI El-Subbagh Bioorganic & medicinal chemistry letters 22 (20), 6318-6323, 2012 | 85 | 2012 |
Synthesis and in vitro anticancer activity of certain novel 1-(2-methyl-6-arylpyridin-3-yl)-3-phenylureas as apoptosis-inducing agents WM Eldehna, GS Hassan, ST Al-Rashood, T Al-Warhi, AE Altyar, ... Journal of enzyme inhibition and medicinal chemistry 34 (1), 322-332, 2019 | 79 | 2019 |
Nonclassical antifolates, Part 4. 5-(2-Aminothiazol-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiols as a new class of DHFR inhibitors: Synthesis, biological evaluation and molecular … HIES Ghada S. Hassan, Shahenda M. El-Messery, Fatmah A European Journal of Medicinal Chemistry, 2013 | 74 | 2013 |
Substituted thiazoles VI. Synthesis and antitumor activity of new 2-acetamido-and 2 or 3-propanamido-thiazole analogs SM El-Messery, GS Hassan, FAM Al-Omary, HI El-Subbagh European journal of medicinal chemistry 54, 615-625, 2012 | 73 | 2012 |
Tumor-associated carbonic anhydrase isoform IX and XII inhibitory properties of certain isatin-bearing sulfonamides endowed with in vitro antitumor activity towards colon cancer WM Eldehna, A Nocentini, ST Al-Rashood, GS Hassan, HM Alkahtani, ... Bioorganic Chemistry 81, 425-432, 2018 | 70 | 2018 |
Synthesis and biological evaluation of some polymethoxylated fused pyridine ring systems as antitumor agents SAF Rostom, GS Hassan, HI El‐Subbagh Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 2009 | 70 | 2009 |
Antitumor properties of certain spirooxindoles towards hepatocellular carcinoma endowed with antioxidant activity ST Al-Rashood, AR Hamed, GS Hassan, HM Alkahtani, AA Almehizia, ... Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 831-839, 2020 | 67 | 2020 |
Novel 4(3H)-quinazolinone analogs: synthesis and anticonvulsant AS El-Azab, SG Abdel-Hamide, MM Sayed-Ahmed, GS Hassan, ... Medicinal Chemistry Research 22 (6), 2815-2827, 2013 | 64 | 2013 |
Nonclassical antifolates, part 5. Benzodiazepine analogs as a new class of DHFR inhibitors: Synthesis, antitumor testing and molecular modeling study HI El-Subbagh, GS Hassan, SM El-Messery, ST Al-Rashood, ... European Journal of Medicinal Chemistry 74, 234-245, 2014 | 59 | 2014 |
SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX WM Eldehna, MF Abo-Ashour, E Berrino, D Vullo, HA Ghabbour, ... Bioorganic chemistry 83, 549-558, 2019 | 58 | 2019 |
Nonclassical antifolates, part 3: Synthesis, biological evaluation and molecular modeling study of some new 2-heteroarylthio-quinazolin-4-ones FAM Al-Omary, GS Hassan, SM El-Messery, MN Nagi, ESE Habib, ... European Journal of Medicinal Chemistry 63, 33-45, 2013 | 57 | 2013 |
Tyrosine kinase inhibition effects of novel Pyrazolo [1, 5-a] pyrimidines and Pyrido [2, 3-d] pyrimidines ligand: Synthesis, biological screening and molecular modeling studies MT El Sayed, HAR Hussein, NM Elebiary, GS Hassan, SM Elmessery, ... Bioorganic Chemistry 78, 312-323, 2018 | 55 | 2018 |
Synthesis, biological evaluation and molecular modeling study of new (1, 2, 4-triazole or 1, 3, 4-thiadiazole)-methylthio-derivatives of quinazolin-4 (3H)-one as DHFR inhibitors YI El-Gazzar, HH Georgey, SM El-Messery, HA Ewida, GS Hassan, ... Bioorganic Chemistry 72, 282-292, 2017 | 53 | 2017 |
Design, synthesis, anti-inflammatory activity and molecular docking of potential novel antipyrine and pyrazolone analogs as cyclooxygenase enzyme (COX) inhibitors MT El Sayed, MAMS El-Sharief, ES Zarie, NM Morsy, AR Elsheakh, ... Bioorganic & medicinal chemistry letters 28 (5), 952-957, 2018 | 52 | 2018 |
Synthesis, biological evaluation and molecular modeling study of 2-(1, 3, 4-thiadiazolyl-thio and 4-methyl-thiazolyl-thio)-quinazolin-4-ones as a new class of DHFR inhibitors ST Al-Rashood, GS Hassan, SM El-Messery, MN Nagi, ESE Habib, ... Bioorganic & Medicinal Chemistry Letters 24 (18), 4557-4567, 2014 | 48 | 2014 |
Synthesis and anticancer activity of new thiazolo [3, 2-a] pyrimidines: DNA binding and molecular modeling study GS Hassan, SM El-Messery, A Abbas Bioorganic Chemistry 74, 41-52, 2017 | 44 | 2017 |
Synthesis and anticonvulsant activity of some new thiazolo [3, 2-a][1, 3] diazepine, benzo [d] thiazolo [5, 2-a][12, 6] diazepine and benzo [d] oxazolo [5, 2-a][12, 6 … HI El-Subbagh, GS Hassan, AS El-Azab, AM Alaa, AA Kadi, AM Al-Obaid, ... European journal of medicinal chemistry 46 (11), 5567-5572, 2011 | 39 | 2011 |
Synthesis, antimicrobial and antiviral testing of some new 1-adamantyl analogues AEMB Ghada S. Hassan, Ali A. El-Emam, Laila M. Gad Saudi Pharmaceutical Journal 18, 123-128, 2010 | 39 | 2010 |