Self-assembling chimeric polypeptide–doxorubicin conjugate nanoparticles that abolish tumours after a single injection JA MacKay, M Chen, JR McDaniel, W Liu, AJ Simnick, A Chilkoti Nature materials 8 (12), 993-999, 2009 | 683 | 2009 |
Analysis of interactions in a tapasin/class I complex provides a mechanism for peptide selection M Chen, M Bouvier The EMBO journal 26 (6), 1681-1690, 2007 | 193 | 2007 |
Gene-directed enzyme prodrug therapy J Zhang, V Kale, M Chen The AAPS journal 17, 102-110, 2015 | 186 | 2015 |
Injectable intratumoral depot of thermally responsive polypeptide–radionuclide conjugates delays tumor progression in a mouse model W Liu, JA MacKay, MR Dreher, M Chen, JR McDaniel, AJ Simnick, ... Journal of controlled Release 144 (1), 2-9, 2010 | 131 | 2010 |
Depletion of PD-1-positive cells ameliorates autoimmune disease P Zhao, P Wang, S Dong, Z Zhou, Y Cao, H Yagita, X He, SG Zheng, ... Nature biomedical engineering 3 (4), 292-305, 2019 | 65 | 2019 |
Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma EM Mastria, M Chen, JR McDaniel, X Li, J Hyun, MW Dewhirst, A Chilkoti Journal of controlled release 208, 52-58, 2015 | 64 | 2015 |
The convergent roles of tapasin and HLA-DM in antigen presentation S Sadegh-Nasseri, M Chen, K Narayan, M Bouvier Trends in immunology 29 (3), 141-147, 2008 | 63 | 2008 |
iTEP nanoparticle-delivered salinomycin displays an enhanced toxicity to cancer stem cells in orthotopic breast tumors P Zhao, S Dong, J Bhattacharyya, M Chen Molecular pharmaceutics 11 (8), 2703-2712, 2014 | 57 | 2014 |
Immune-tolerant elastin-like polypeptides (iTEPs) and their application as CTL vaccine carriers S Cho, S Dong, KN Parent, M Chen Journal of drug targeting 24 (4), 328-339, 2016 | 53 | 2016 |
Discovery of a 19F MRI sensitive salinomycin derivative with high cytotoxicity towards cancer cells Q Shi, Y Li, S Bo, X Li, P Zhao, Q Liu, Z Yang, H Cong, H Deng, M Chen, ... Chemical communications 52 (29), 5136-5139, 2016 | 45 | 2016 |
The calcium-and zinc-responsive regions of calreticulin reside strictly in the N-/C-domain Y Tan, M Chen, Z Li, K Mabuchi, M Bouvier Biochimica et Biophysica Acta (BBA)-General Subjects 1760 (5), 745-753, 2006 | 43 | 2006 |
An iTEP-salinomycin nanoparticle that specifically and effectively inhibits metastases of 4T1 orthotopic breast tumors P Zhao, G Xia, S Dong, ZX Jiang, M Chen Biomaterials 93, 1-9, 2016 | 40 | 2016 |
An albumin-binding polypeptide both targets cytotoxic T lymphocyte vaccines to lymph nodes and boosts vaccine presentation by dendritic cells P Wang, P Zhao, S Dong, T Xu, X He, M Chen Theranostics 8 (1), 223, 2018 | 33 | 2018 |
An Anti-Programmed death-1 antibody (αPD-1) fusion protein that self-assembles into a multivalent and functional αPD-1 nanoparticle P Zhao, D Atanackovic, S Dong, H Yagita, X He, M Chen Molecular pharmaceutics 14 (5), 1494-1500, 2017 | 31 | 2017 |
Immune checkpoints, a novel class of therapeutic targets for autoimmune diseases Y Zhai, R Moosavi, M Chen Frontiers in Immunology 12, 645699, 2021 | 24 | 2021 |
A characterization of the lumenal region of human tapasin reveals the presence of two structural domains M Chen, WF Stafford, G Diedrich, A Khan, M Bouvier Biochemistry 41 (49), 14539-14545, 2002 | 18 | 2002 |
Direct loading of CTL epitopes onto MHC class I complexes on dendritic cell surface in vivo P Wang, S Dong, P Zhao, X He, M Chen Biomaterials 182, 92-103, 2018 | 14 | 2018 |
A comparison study of iTEP nanoparticle-based CTL vaccine carriers revealed a surprise relationship between the stability and efficiency of the carriers S Dong, T Xu, P Zhao, KN Parent, M Chen Theranostics 6 (5), 666, 2016 | 13 | 2016 |
Direct loading of iTEP-delivered CTL epitope onto MHC class I complexes on the dendritic cell surface S Dong, P Wang, P Zhao, M Chen Molecular pharmaceutics 14 (10), 3312-3321, 2017 | 10 | 2017 |
Engineering of a self-adjuvanted iTEP-delivered CTL vaccine S Dong, T Xu, P Wang, P Zhao, M Chen Acta Pharmacologica Sinica 38 (6), 914-923, 2017 | 9 | 2017 |