| Histone H4 lysine 16 acetylation regulates cellular lifespan W Dang, KK Steffen, R Perry, JA Dorsey, FB Johnson, A Shilatifard, ... Nature 459 (7248), 802-807, 2009 | 731 | 2009 |
| Protein acetylation microarray reveals that NuA4 controls key metabolic target regulating gluconeogenesis Y Lin, J Lu, J Zhang, W Walter, W Dang, J Wan, SC Tao, J Qian, Y Zhao, ... Cell 136 (6), 1073-1084, 2009 | 343 | 2009 |
| SIRT6 is responsible for more efficient DNA double-strand break repair in long-lived species X Tian, D Firsanov, Z Zhang, Y Cheng, L Luo, G Tombline, R Tan, ... Cell 177 (3), 622-638. e22, 2019 | 255 | 2019 |
| H3K36 methylation promotes longevity by enhancing transcriptional fidelity P Sen, W Dang, G Donahue, J Dai, J Dorsey, X Cao, W Liu, K Cao, ... Genes & development 29 (13), 1362-1376, 2015 | 229 | 2015 |
| Topography of the ISW2–nucleosome complex: insights into nucleosome spacing and chromatin remodeling MN Kagalwala, BJ Glaus, W Dang, M Zofall, B Bartholomew The EMBO journal 23 (10), 2092-2104, 2004 | 187 | 2004 |
| The controversial world of sirtuins W Dang Drug Discovery Today: Technologies 12, e9-e17, 2014 | 183 | 2014 |
| High-throughput analysis of yeast replicative aging using a microfluidic system MC Jo, W Liu, L Gu, W Dang, L Qin Proceedings of the National Academy of Sciences 112 (30), 9364-9369, 2015 | 182 | 2015 |
| Domain architecture of the catalytic subunit in the ISW2-nucleosome complex W Dang, B Bartholomew Molecular and cellular biology 27 (23), 8306-8317, 2007 | 146 | 2007 |
| MYST protein acetyltransferase activity requires active site lysine autoacetylation H Yuan, D Rossetto, H Mellert, W Dang, M Srinivasan, J Johnson, ... The EMBO journal 31 (1), 58-70, 2012 | 129 | 2012 |
| Regulation of ISW2 by concerted action of histone H4 tail and extranucleosomal DNA W Dang, MN Kagalwala, B Bartholomew Molecular and cellular biology 26 (20), 7388-7396, 2006 | 116 | 2006 |
| Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence P Sen, Y Lan, CY Li, S Sidoli, G Donahue, Z Dou, B Frederick, Q Chen, ... Molecular cell 73 (4), 684-698. e8, 2019 | 111 | 2019 |
| Histone methylation and aging: lessons learned from model systems BS McCauley, W Dang Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (12 …, 2014 | 103 | 2014 |
| Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response W Dang, GL Sutphin, JA Dorsey, GL Otte, K Cao, RM Perry, JJ Wanat, ... Cell metabolism 19 (6), 952-966, 2014 | 86 | 2014 |
| Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons JF Moruno-Manchon, P Lejault, Y Wang, B McCauley, P Honarpisheh, ... Elife 9, e52283, 2020 | 70 | 2020 |
| Chromatin architectural changes during cellular senescence and aging L Sun, R Yu, W Dang Genes 9 (4), 211, 2018 | 70 | 2018 |
| The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction MA McCormick, AG Mason, SJ Guyenet, W Dang, RM Garza, MK Ting, ... Cell reports 8 (2), 477-486, 2014 | 68 | 2014 |
| Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction ML Kozak, A Chavez, W Dang, SL Berger, A Ashok, X Guo, FB Johnson The EMBO journal 29 (1), 158-170, 2010 | 63 | 2010 |
| Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast C Beaupere, L Dinatto, BM Wasko, RB Chen, L VanValkenburg, ... Proceedings of the National Academy of Sciences 115 (38), 9586-9591, 2018 | 46 | 2018 |
| Loss of Nat4 and its associated histone H4 N‐terminal acetylation mediates calorie restriction‐induced longevity D Molina‐Serrano, V Schiza, C Demosthenous, E Stavrou, J Oppelt, ... EMBO reports 17 (12), 1829-1843, 2016 | 45 | 2016 |
| The Dpb4 subunit of ISW2 is anchored to extranucleosomal DNA W Dang, MN Kagalwala, B Bartholomew Journal of Biological Chemistry 282 (27), 19418-19425, 2007 | 43 | 2007 |
Shelley L BergerProfessor of Cell and Developmental Biology, University of Pennsylvania在 upenn.edu 的电子邮件经过验证
