DNA sensing in mismatch repair-deficient tumor cells is essential for anti-tumor immunity C Lu, J Guan, S Lu, Q Jin, B Rousseau, T Lu, D Stephens, H Zhang, J Zhu, ... Cancer cell 39 (1), 96-108. e6, 2021 | 192 | 2021 |
MLH1 deficiency-triggered DNA hyperexcision by exonuclease 1 activates the cGAS-STING pathway J Guan, C Lu, Q Jin, H Lu, X Chen, L Tian, Y Zhang, J Ortega, J Zhang, ... Cancer cell 39 (1), 109-121. e5, 2021 | 137 | 2021 |
Tumor cells suppress radiation-induced immunity by hijacking caspase 9 signaling C Han, Z Liu, Y Zhang, A Shen, C Dong, A Zhang, C Moore, Z Ren, C Lu, ... Nature immunology 21 (5), 546-554, 2020 | 100 | 2020 |
eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer S Suresh, BB Chen, J Zhu, RJ Golden, C Lu, BM Evers, N Novaresi, ... Nature cancer 1 (5), 533-545, 2020 | 89 | 2020 |
Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load HD Li, I Cuevas, M Zhang, C Lu, MM Alam, YX Fu, MJ You, EA Akbay, ... The Journal of Clinical Investigation 128 (9), 4179-4191, 2018 | 73 | 2018 |
Dual targeting of CTLA-4 and CD47 on Treg cells promotes immunity against solid tumors A Zhang, Z Ren, KF Tseng, X Liu, H Li, C Lu, Y Cai, JD Minna, YX Fu Science translational medicine 13 (605), eabg8693, 2021 | 47 | 2021 |
Hypofractionated EGFR tyrosine kinase inhibitor limits tumor relapse through triggering innate and adaptive immunity Z Liu, C Han, C Dong, A Shen, E Hsu, Z Ren, C Lu, L Liu, A Zhang, ... Science immunology 4 (38), eaav6473, 2019 | 36 | 2019 |
A PoleP286R mouse model of endometrial cancer recapitulates high mutational burden and immunotherapy response HD Li, C Lu, H Zhang, Q Hu, J Zhang, IC Cuevas, SS Sahoo, M Aguilar, ... JCI insight 5 (14), 2020 | 31 | 2020 |
Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated antitumor immunity L Liu, J Chen, H Zhang, J Ye, C Moore, C Lu, Y Fang, YX Fu, B Li Nature cancer 3 (4), 437-452, 2022 | 23 | 2022 |
DNAJA2 deficiency activates cGAS-STING pathway via the induction of aberrant mitosis and chromosome instability Y Huang, C Lu, H Wang, L Gu, YX Fu, GM Li Nature communications 14 (1), 5246, 2023 | 4 | 2023 |
Precision intervention of cell type-specific targeting is required for future cancer immunotherapy Y Cai, A Zhang, C Lu Medical Review 2 (6), 553-554, 2023 | 4 | 2023 |
800 Dual targeting of CTLA-4 and CD47 on Treg cells rejuvenates immunity against solid tumors A Zhang, Z Ren, K Tseng, X Liu, H Li, C Lu, Y Cai, J Minna, YX Fu Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021 | | 2021 |