关注
Shenyan Gu
Shenyan Gu
Ph.D
在 its.jnj.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Botulinum Neurotoxin Is Shielded by NTNHA in an Interlocked Complex
S Gu, S Rumpel, J Zhou, J Strotmeier, H Bigalke, K Perry, CB Shoemaker, ...
Science 335 (6071), 977-981, 2012
2452012
Crystal structure and association behaviour of the GluR2 amino‐terminal domain
R Jin, SK Singh, S Gu, H Furukawa, AI Sobolevsky, J Zhou, Y Jin, ...
The EMBO journal 28 (12), 1812-1823, 2009
2022009
Structural basis of agrin–LRP4–MuSK signaling
Y Zong, B Zhang, S Gu, K Lee, J Zhou, G Yao, D Figueiredo, K Perry, ...
Genes & Development 26 (3), 247-258, 2012
1852012
Brain α7 nicotinic acetylcholine receptor assembly requires NACHO
S Gu, JA Matta, B Lord, AW Harrington, SW Sutton, WB Davini, DS Bredt
Neuron 89 (5), 948-955, 2016
1562016
Structure of a bimodular botulinum neurotoxin complex provides insights into its oral toxicity
K Lee, S Gu, L Jin, TTN Le, LW Cheng, J Strotmeier, AM Kruel, G Yao, ...
PLoS pathogens 9 (10), e1003690, 2013
1382013
Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex
K Lee, X Zhong, S Gu, AM Kruel, MB Dorner, K Perry, A Rummel, M Dong, ...
Science 344 (6190), 1405-1410, 2014
1252014
Assembly and function of the botulinum neurotoxin progenitor complex.
S Gu, R Jin
Current topics in microbiology and immunology 364, 21, 2013
942013
NACHO mediates nicotinic acetylcholine receptor function throughout the brain
JA Matta, S Gu, WB Davini, B Lord, ER Siuda, AW Harrington, DS Bredt
Cell reports 19 (4), 688-696, 2017
812017
The biological activity of botulinum neurotoxin type C is dependent upon novel types of ganglioside binding sites
J Strotmeier, S Gu, S Jutzi, S Mahrhold, J Zhou, A Pich, T Eichner, ...
Molecular microbiology 81 (1), 143-156, 2011
772011
Getting a handle on neuropharmacology by targeting receptor-associated proteins
MP Maher, JA Matta, S Gu, M Seierstad, DS Bredt
Neuron 96 (5), 989-1001, 2017
612017
Nicotinic acetylcholine receptor redux: Discovery of accessories opens therapeutic vistas
JA Matta, S Gu, WB Davini, DS Bredt
Science 373 (6556), eabg6539, 2021
442021
Structural basis of the pH-dependent assembly of a botulinum neurotoxin complex
T Matsui, S Gu, K Lam, LG Carter, A Rummel, II Mathews, R Jin
Journal of molecular biology 426 (22), 3773-3782, 2014
352014
Crystal structure of the glutamate receptor GluA1 N-terminal domain
G Yao, Y Zong, S Gu, J Zhou, H Xu, II Mathews, R Jin
Biochemical Journal 438 (2), 255-263, 2011
312011
α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins
GB Dawe, H Yu, S Gu, AN Blackler, JA Matta, ER Siuda, EB Rex, ...
Nature Communications 10 (1), 2746, 2019
302019
Crystal structure of human phosphomavelonate kinase at 1.8 Å resolution
Q Chang, XX Yan, SY Gu, JF Liu, DC Liang
Proteins: Structure, Function, and Bioinformatics 73 (1), 254-258, 2008
282008
Botulinum neurotoxin A complex recognizes host carbohydrates through its hemagglutinin component
G Yao, K Lee, S Gu, KH Lam, R Jin
Toxins 6 (2), 624-635, 2014
252014
Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology
M Dhara, JA Matta, M Lei, D Knowland, H Yu, S Gu, DS Bredt
Nature Communications 11 (1), 2799, 2020
242020
α6-Containing nicotinic acetylcholine receptor reconstitution involves mechanistically distinct accessory components
S Gu, JA Matta, WB Davini, GB Dawe, B Lord, DS Bredt
Cell Reports 26 (4), 866-874. e3, 2019
232019
Hair cell α9α10 nicotinic acetylcholine receptor functional expression regulated by ligand binding and deafness gene products
S Gu, D Knowland, JA Matta, ML O’Carroll, WB Davini, M Dhara, ...
Proceedings of the National Academy of Sciences 117 (39), 24534-24544, 2020
202020
NACHO engages N-glycosylation ER chaperone pathways for α7 nicotinic receptor assembly
HJ Kweon, S Gu, E Witham, M Dhara, H Yu, ED Mandon, A Jawhari, ...
Cell reports 32 (6), 2020
172020
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