Human heart-forming organoids recapitulate early heart and foregut development L Drakhlis, S Biswanath, CM Farr, V Lupanow, J Teske, K Ritzenhoff, ... Nature Biotechnology 39 (6), 737-746, 2021 | 261 | 2021 |
Controlling expansion and cardiomyogenic differentiation of human pluripotent stem cells in scalable suspension culture H Kempf, R Olmer, C Kropp, M Rückert, M Jara-Avaca, D Robles-Diaz, ... Stem cell reports 3 (6), 1132-1146, 2014 | 242 | 2014 |
Cardiac differentiation of human pluripotent stem cells in scalable suspension culture H Kempf, C Kropp, R Olmer, U Martin, R Zweigerdt Nature protocols 10 (9), 1345-1361, 2015 | 168 | 2015 |
The use of agarose microwells for scalable embryoid body formation and cardiac differentiation of human and murine pluripotent stem cells J Dahlmann, G Kensah, H Kempf, D Skvorc, A Gawol, DA Elliott, G Dräger, ... Biomaterials 34 (10), 2463-2471, 2013 | 151 | 2013 |
Impact of Feeding Strategies on the Scalable Expansion of Human Pluripotent Stem Cells in Single‐Use Stirred Tank Bioreactors C Kropp, H Kempf, C Halloin, D Robles-Diaz, A Franke, T Scheper, ... Stem Cells Translational Medicine 5 (10), 1289-1301, 2016 | 144 | 2016 |
Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections M Ackermann, H Kempf, M Hetzel, C Hesse, AR Hashtchin, K Brinkert, ... Nature communications 9 (1), 5088, 2018 | 131 | 2018 |
Large-scale production of human pluripotent stem cell derived cardiomyocytes H Kempf, B Andree, R Zweigerdt Advanced drug delivery reviews 96, 18-30, 2016 | 128 | 2016 |
Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells H Kempf, R Olmer, A Haase, A Franke, E Bolesani, K Schwanke, ... Nature communications 7 (1), 13602, 2016 | 124 | 2016 |
Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture C Halloin, K Schwanke, W Löbel, A Franke, M Szepes, S Biswanath, ... Stem cell reports 13 (2), 366-379, 2019 | 85 | 2019 |
Stiff matrix induces switch to pure β-cardiac myosin heavy chain expression in human ESC-derived cardiomyocytes N Weber, K Schwanke, S Greten, M Wendland, B Iorga, M Fischer, ... Basic research in cardiology 111, 1-16, 2016 | 58 | 2016 |
Airway basal cells show a dedifferentiated KRT17highPhenotype and promote fibrosis in idiopathic pulmonary fibrosis B Jaeger, JC Schupp, L Plappert, O Terwolbeck, N Artysh, G Kayser, ... Nature communications 13 (1), 5637, 2022 | 52 | 2022 |
iPSC-derived macrophages effectively treat pulmonary alveolar proteinosis in Csf2rb-deficient mice A Mucci, E Lopez-Rodriguez, M Hetzel, S Liu, T Suzuki, C Happle, ... Stem cell reports 11 (3), 696-710, 2018 | 50 | 2018 |
Expansion of functional personalized cells with specific transgene combinations C Lipps, F Klein, T Wahlicht, V Seiffert, M Butueva, J Zauers, T Truschel, ... Nature communications 9 (1), 994, 2018 | 48 | 2018 |
Continuous human iPSC-macrophage mass production by suspension culture in stirred tank bioreactors M Ackermann, A Rafiei Hashtchin, F Manstein, M Carvalho Oliveira, ... Nature Protocols 17 (2), 513-539, 2022 | 45 | 2022 |
Comparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation A735V of NaV1.5 sodium channels J de la Roche, P Angsutararux, H Kempf, M Janan, E Bolesani, ... Scientific reports 9 (1), 11173, 2019 | 44 | 2019 |
Distinct regulation of mitogen-activated protein kinase activities is coupled with enhanced cardiac differentiation of human embryonic stem cells H Kempf, M Lecina, S Ting, R Zweigerdt, S Oh Stem cell research 7 (3), 198-209, 2011 | 39 | 2011 |
A Cardiac Cell Outgrowth Assay for Evaluating Drug Compounds Using a Cardiac Spheroid-on-a-Chip Device J Christoffersson, F Meier, H Kempf, K Schwanke, M Coffee, M Beilmann, ... Bioengineering 5 (2), 36, 2018 | 33 | 2018 |
Scalable production of tissue-like vascularized liver organoids from human PSCs SP Harrison, R Siller, Y Tanaka, ME Chollet, ME de la Morena-Barrio, ... Experimental & Molecular Medicine 55 (9), 2005-2024, 2023 | 28 | 2023 |
Scalable cardiac differentiation of pluripotent stem cells using specific growth factors and small molecules H Kempf, R Zweigerdt Springer, Berlin, Heidelberg, 2017 | 26 | 2017 |
Proteomic analysis of human pluripotent stem cell cardiomyogenesis revealed altered expression of metabolic enzymes and PDLIM5 isoforms SA Konze, S Werneburg, A Oberbeck, R Olmer, H Kempf, M Jara-Avaca, ... Journal of Proteome Research 16 (3), 1133-1149, 2017 | 25 | 2017 |