Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus HX Liao, R Lynch, T Zhou, F Gao, SM Alam, SD Boyd, AZ Fire, KM Roskin, ... Nature 496 (7446), 469-476, 2013 | 1122 | 2013 |
Effect of HIV antibody VRC01 on viral rebound after treatment interruption KJ Bar, MC Sneller, LJ Harrison, JS Justement, ET Overton, ME Petrone, ... New England Journal of Medicine 375 (21), 2037-2050, 2016 | 473 | 2016 |
Virologic effects of broadly neutralizing antibody VRC01 administration during chronic HIV-1 infection RM Lynch, E Boritz, EE Coates, A DeZure, P Madden, P Costner, ... Science translational medicine 7 (319), 319ra206-319ra206, 2015 | 461 | 2015 |
Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ... Cell 161 (6), 1280-1292, 2015 | 321 | 2015 |
Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies F Gao, M Bonsignori, HX Liao, A Kumar, SM Xia, X Lu, F Cai, KK Hwang, ... Cell 158 (3), 481-491, 2014 | 310 | 2014 |
Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults Clinical & Experimental Immunology 182 (3), 289-301, 2015 | 273 | 2015 |
Differential induction of mucosal and systemic antibody responses in women after nasal, rectal, or vaginal immunization: influence of the menstrual cycle PA Kozlowski, SB Williams, RM Lynch, TP Flanigan, RR Patterson, ... The Journal of Immunology 169 (1), 566-574, 2002 | 266 | 2002 |
Maturation and diversity of the VRC01-antibody lineage over 15 years of chronic HIV-1 infection X Wu, Z Zhang, CA Schramm, MG Joyce, Y Do Kwon, T Zhou, Z Sheng, ... Cell 161 (3), 470-485, 2015 | 260 | 2015 |
A dominant complement fixation pathway for pneumococcal polysaccharides initiated by SIGN-R1 interacting with C1q YS Kang, Y Do, HK Lee, SH Park, C Cheong, RM Lynch, JM Loeffler, ... Cell 125 (1), 47-58, 2006 | 248 | 2006 |
New member of the V1V2-directed CAP256-VRC26 lineage that shows increased breadth and exceptional potency NA Doria-Rose, JN Bhiman, RS Roark, CA Schramm, J Gorman, ... Journal of virology 90 (1), 76-91, 2016 | 242 | 2016 |
Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways R Rong, B Li, RM Lynch, RE Haaland, MK Murphy, J Mulenga, SA Allen, ... PLoS pathogens 5 (9), e1000594, 2009 | 236 | 2009 |
Prescribed dietary phosphate restriction and survival among hemodialysis patients KE Lynch, R Lynch, GC Curhan, SM Brunelli Clinical Journal of the American Society of Nephrology 6 (3), 620-629, 2011 | 198 | 2011 |
Ion mobilty spectrometer incorporating an ion guide in combination with an MS device AV Loboda US Patent 6,744,043, 2004 | 191 | 2004 |
HIV-1 fitness cost associated with escape from the VRC01 class of CD4 binding site neutralizing antibodies RM Lynch, P Wong, L Tran, S O'Dell, MC Nason, Y Li, X Wu, JR Mascola Journal of virology 89 (8), 4201-4213, 2015 | 163 | 2015 |
The development of CD4 binding site antibodies during HIV-1 infection RM Lynch, L Tran, MK Louder, SD Schmidt, M Cohen, ... Journal of virology 86 (14), 7588-7595, 2012 | 157 | 2012 |
Modified wick method using Weck-Cel sponges for collection of human rectal secretions and analysis of mucosal HIV antibody PA Kozlowski, RM Lynch, RR Patterson, S Cu-Uvin, TP Flanigan, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 24 (4), 297-309, 2000 | 130 | 2000 |
Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection T Yamamoto, RM Lynch, R Gautam, R Matus-Nicodemos, SD Schmidt, ... Science translational medicine 7 (298), 298ra120-298ra120, 2015 | 121 | 2015 |
An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1 M Bonsignori, K Wiehe, SK Grimm, R Lynch, G Yang, DM Kozink, F Perrin, ... The Journal of clinical investigation 124 (4), 1835-1843, 2014 | 114 | 2014 |
Appreciating HIV type 1 diversity: subtype differences in Env RM Lynch, T Shen, S Gnanakaran, CA Derdeyn AIDS research and human retroviruses 25 (3), 237-248, 2009 | 107 | 2009 |
Analysis of immunoglobulin transcripts and hypermutation following SHIVAD8 infection and protein-plus-adjuvant immunization JR Francica, Z Sheng, Z Zhang, Y Nishimura, M Shingai, A Ramesh, ... Nature communications 6 (1), 6565, 2015 | 96 | 2015 |