关注
Kelvin Wu
Kelvin Wu
在 g.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
A synthetic antibiotic class overcoming bacterial multidrug resistance
MJ Mitcheltree, A Pisipati, EA Syroegin, KJ Silvestre, D Klepacki, ...
Nature 599 (7885), 507-512, 2021
1462021
The l‐Alanosine Gene Cluster Encodes a Pathway for Diazeniumdiolate Biosynthesis
TL Ng, ME McCallum, CR Zheng, JX Wang, KJY Wu, EP Balskus
ChemBioChem 21 (8), 1155-1160, 2020
312020
Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR
N Obana, H Takada, C Crowe-McAuliffe, M Iwamoto, AA Egorov, KJY Wu, ...
Nucleic Acids Research 51 (9), 4536-4554, 2023
202023
Expression of Bacillus subtilis ABCF antibiotic resistance factor VmlR is regulated by RNA polymerase pausing, transcription attenuation, translation attenuation …
H Takada, ZF Mandell, H Yakhnin, A Glazyrina, S Chiba, T Kurata, ...
Nucleic Acids Research 50 (11), 6174-6189, 2022
172022
An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance
KJY Wu, BIC Tresco, A Ramkissoon, EV Aleksandrova, EA Syroegin, ...
Science 383 (6684), 721-726, 2024
122024
Synthetic oxepanoprolinamide iboxamycin is active against Listeria monocytogenes despite the intrinsic resistance mediated by VgaL/Lmo0919 ABCF ATPase
T Brodiazhenko, KJ Turnbull, KJY Wu, H Takada, BIC Tresco, T Tenson, ...
JAC-antimicrobial resistance 4 (3), dlac061, 2022
72022
Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it
EV Aleksandrova, KJY Wu, BIC Tresco, EA Syroegin, EE Killeavy, ...
Nature Chemical Biology, 1-10, 2024
52024
A synthetic antibiotic scaffold effective against multidrug-resistant bacterial pathogens
M Mitcheltree, A Pisipati, EA Syroegin, KJ Silvestre, D Klepacki, J Mason, ...
52021
A method for tritiation of iboxamycin permits measurement of its ribosomal binding
KJY Wu, D Klepacki, AS Mankin, AG Myers
Bioorganic & Medicinal Chemistry Letters 91, 129364, 2023
32023
Synthetic oxepanoprolinamide iboxamycin is highly active against human pathogen Listeria monocytogenes
T Brodiazhenko, KJ Turnbull, KJY Wu, H Takada, BIC Tresco, T Tenson, ...
bioRxiv, 2022.02. 28.482263, 2022
22022
Structural basis of Cfr-mediated antimicrobial resistance and mechanisms for its evasion
EV Aleksandrova, KJY Wu, BIC Tresco, EA Syroegin, EE Killeavy, ...
bioRxiv, 2023
12023
[3+ 2] Dipolar Cycloaddition of a Stabilized Azomethine Ylide and an Electron-Deficient Dipolarophile: Revision of Regioselectivity
KJY Wu, AE Benedetto, AG Myers
The Journal of organic chemistry 88 (3), 1907-1908, 2023
12023
Discovery of a broad-spectrum, fluorinated macrobicyclic antibiotic through chemical synthesis
B Tresco, K Wu, A Ramkissoon, E Aleksandrova, M Purdy, D See, R Liu, ...
2024
Synthetic lincosamides iboxamycin and cresomycin are active against ocular multidrug-resistant methicillin-resistant S. aureus carrying erm genes
C André, KJY Wu, AG Myers, PJM Bispo
Journal of Global Antimicrobial Resistance, 2024
2024
A Synthetic Antibiotic Scaffold Effective Against Multidrug-Resistant Bacterial Pathogens (preprint)
M Mitcheltree, A Pisipati, EA Syroegin, KJ Silvestre, D Klepacki, J Mason, ...
2021
系统目前无法执行此操作,请稍后再试。
文章 1–15