24-hydroxycholesterol sulfation by human cytosolic sulfotransferases: formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of … IT Cook, Z Duniec-Dmuchowski, TA Kocarek, M Runge-Morris, CN Falany Drug metabolism and disposition 37 (10), 2069-2078, 2009 | 97 | 2009 |
The gate that governs sulfotransferase selectivity I Cook, T Wang, SC Almo, J Kim, CN Falany, TS Leyh Biochemistry 52 (2), 415-424, 2013 | 79 | 2013 |
High accuracy in silico sulfotransferase models I Cook, T Wang, CN Falany, TS Leyh Journal of biological chemistry 288 (48), 34494-34501, 2013 | 53 | 2013 |
Paradigms of sulfotransferase catalysis: the mechanism of SULT2A1 T Wang, I Cook, CN Falany, TS Leyh Journal of Biological Chemistry 289 (38), 26474-26480, 2014 | 50 | 2014 |
A nucleotide-gated molecular pore selects sulfotransferase substrates I Cook, T Wang, CN Falany, TS Leyh Biochemistry 51 (28), 5674-5683, 2012 | 50 | 2012 |
Structural rearrangement of SULT2A1: effects on dehydroepiandrosterone and raloxifene sulfation IT Cook, TS Leyh, SA Kadlubar, CN Falany Hormone molecular biology and clinical investigation 1 (2), 81-87, 2010 | 44 | 2010 |
Potent inhibition of human sulfotransferase 1A1 by 17α-ethinylestradiol: role of 3′-phosphoadenosine 5′-phosphosulfate binding and structural rearrangements in regulating … KJ Rohn, IT Cook, TS Leyh, SA Kadlubar, CN Falany Drug Metabolism and Disposition 40 (8), 1588-1595, 2012 | 42 | 2012 |
Structure, dynamics and selectivity in the sulfotransferase family TS Leyh, I Cook, T Wang Drug metabolism reviews 45 (4), 423-430, 2013 | 36 | 2013 |
3′-Phosphoadenosine 5′-phosphosulfate allosterically regulates sulfotransferase turnover T Wang, I Cook, TS Leyh Biochemistry 53 (44), 6893-6900, 2014 | 34 | 2014 |
Sulfotransferase 1A1 substrate selectivity: a molecular clamp mechanism I Cook, T Wang, TS Leyh Biochemistry 54 (39), 6114-6122, 2015 | 30 | 2015 |
Testing the sulfotransferase molecular pore hypothesis I Cook, T Wang, SC Almo, J Kim, CN Falany, TS Leyh Journal of Biological Chemistry 288 (12), 8619-8626, 2013 | 30 | 2013 |
The NSAID allosteric site of human cytosolic sulfotransferases T Wang, I Cook, TS Leyh Journal of Biological Chemistry 292 (49), 20305-20312, 2017 | 25 | 2017 |
The allosteric binding sites of sulfotransferase 1A1 I Cook, T Wang, CN Falany, TS Leyh Drug Metabolism and Disposition 43 (3), 418-423, 2015 | 25 | 2015 |
Sulfation of fulvestrant by human liver cytosols and recombinant SULT1A1 and SULT1E1 VK Edavana, X Yu, IB Dhakal, S Williams, B Ning, IT Cook, D Caldwell, ... Pharmacogenomics and personalized medicine, 137-145, 2011 | 24 | 2011 |
The structure of the catechin-binding site of human sulfotransferase 1A1 I Cook, T Wang, M Girvin, TS Leyh Proceedings of the National Academy of Sciences 113 (50), 14312-14317, 2016 | 23 | 2016 |
Design and interpretation of human sulfotransferase 1A1 assays T Wang, I Cook, TS Leyh Drug Metabolism and Disposition 44 (4), 481-484, 2016 | 22 | 2016 |
Controlling principles for prior probability assignments in nuclear risk assessment I Cook, SD Unwin Nuclear Science and Engineering 94 (2), 107-119, 1986 | 22 | 1986 |
Isozyme specific allosteric regulation of human sulfotransferase 1A1 T Wang, I Cook, TS Leyh Biochemistry 55 (29), 4036-4046, 2016 | 20 | 2016 |
Tetrahydrobiopterin regulates monoamine neurotransmitter sulfonation I Cook, T Wang, TS Leyh Proceedings of the National Academy of Sciences 114 (27), E5317-E5324, 2017 | 19 | 2017 |
Isoform-specific therapeutic control of sulfonation in humans I Cook, T Wang, TS Leyh Biochemical pharmacology 159, 25-31, 2019 | 16 | 2019 |