A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions G Noel, NW Baetz, JF Staab, M Donowitz, O Kovbasnjuk, MF Pasetti, ... Scientific reports 7 (1), 45270, 2017 | 402 | 2017 |
Human intestinal enteroids: a new model to study human rotavirus infection, host restriction, and pathophysiology K Saxena, SE Blutt, K Ettayebi, XL Zeng, JR Broughman, SE Crawford, ... Journal of virology 90 (1), 43-56, 2016 | 376 | 2016 |
Human enteroids/colonoids and intestinal organoids functionally recapitulate normal intestinal physiology and pathophysiology NC Zachos, O Kovbasnjuk, J Foulke-Abel, J In, SE Blutt, HR De Jonge, ... Journal of Biological Chemistry 291 (8), 3759-3766, 2016 | 291 | 2016 |
Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle L Vernetti, A Gough, N Baetz, S Blutt, JR Broughman, JA Brown, ... Scientific reports 7 (1), 42296, 2017 | 258 | 2017 |
Enterohemorrhagic Escherichia coli reduces mucus and intermicrovillar bridges in human stem cell-derived colonoids J In, J Foulke-Abel, NC Zachos, AM Hansen, JB Kaper, HD Bernstein, ... Cellular and molecular gastroenterology and hepatology 2 (1), 48-62. e3, 2016 | 256 | 2016 |
The glycosphingolipid globotriaosylceramide in the metastatic transformation of colon cancer O Kovbasnjuk, R Mourtazina, B Baibakov, T Wang, C Elowsky, MA Choti, ... Proceedings of the National Academy of Sciences 102 (52), 19087-19092, 2005 | 223 | 2005 |
Human enteroids as an ex-vivo model of host–pathogen interactions in the gastrointestinal tract J Foulke-Abel, J In, O Kovbasnjuk, NC Zachos, K Ettayebi, SE Blutt, ... Experimental Biology and Medicine 239 (9), 1124-1134, 2014 | 192 | 2014 |
Human enteroids as a model of upper small intestinal ion transport physiology and pathophysiology J Foulke-Abel, J In, J Yin, NC Zachos, O Kovbasnjuk, MK Estes, ... Gastroenterology 150 (3), 638-649. e8, 2016 | 190 | 2016 |
Human mini-guts: new insights into intestinal physiology and host–pathogen interactions JG In, J Foulke-Abel, MK Estes, NC Zachos, O Kovbasnjuk, M Donowitz Nature reviews Gastroenterology & hepatology 13 (11), 633-642, 2016 | 139 | 2016 |
Role of lipid rafts in Shiga toxin 1 interaction with the apical surface of Caco-2 cells O Kovbasnjuk, M Edidin, M Donowitz Journal of cell science 114 (22), 4025-4031, 2001 | 136 | 2001 |
A paradox of transcriptional and functional innate interferon responses of human intestinal enteroids to enteric virus infection K Saxena, LM Simon, XL Zeng, SE Blutt, SE Crawford, NP Sastri, ... Proceedings of the National Academy of Sciences 114 (4), E570-E579, 2017 | 124 | 2017 |
In, J.; Blutt, SE; de Jonge, HR; Estes, MK; Donowitz, M. Human enteroids/colonoids and intestinal organoids functionally recapitulate normal intestinal physiology and … NC Zachos, O Kovbasnjuk, J Foulke-Abel J. Biol. Chem 291, 3759-3766, 2016 | 124 | 2016 |
Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis I Malyukova, KF Murray, C Zhu, E Boedeker, A Kane, K Patterson, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 296 (1 …, 2009 | 112 | 2009 |
MicroRNA in pancreatic cancer: from biology to therapeutic potential M Rawat, K Kadian, Y Gupta, A Kumar, PSG Chain, O Kovbasnjuk, ... Genes 10 (10), 752, 2019 | 105 | 2019 |
Na+/H+ exchanger NHE3 activity and trafficking are lipid Raft-dependent R Murtazina, O Kovbasnjuk, M Donowitz, X Li Journal of Biological Chemistry 281 (26), 17845-17855, 2006 | 102 | 2006 |
The NHE3 juxtamembrane cytoplasmic domain directly binds ezrin: dual role in NHE3 trafficking and mobility in the brush border B Cha, M Tse, C Yun, O Kovbasnjuk, S Mohan, A Hubbard, M Arpin, ... Molecular biology of the cell 17 (6), 2661-2673, 2006 | 95 | 2006 |
D-Glucose Acts via Sodium/Glucose Cotransporter 1 to Increase NHE3 in Mouse Jejunal Brush Border by a Na+/H+ Exchange Regulatory Factor 2–Dependent Process R Lin, R Murtazina, B Cha, M Chakraborty, R Sarker, TE Chen, Z Lin, ... Gastroenterology 140 (2), 560-571, 2011 | 94 | 2011 |
Water does not flow across the tight junctions of MDCK cell epithelium O Kovbasnjuk, JP Leader, AM Weinstein, KR Spring Proceedings of the National Academy of Sciences 95 (11), 6526-6530, 1998 | 89 | 1998 |
Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na+/H+ exchanger regulatory factor 1 (NHERF1) null mice: cAMP inhibition is differentially dependent … R Murtazina, O Kovbasnjuk, NC Zachos, X Li, Y Chen, A Hubbard, ... Journal of Biological Chemistry 282 (34), 25141-25151, 2007 | 85 | 2007 |
Na+/H+ exchanger 3 is in large complexes in the center of the apical surface of proximal tubule-derived OK cells S Akhter, O Kovbasnjuk, X Li, M Cavet, J Noel, M Arpin, AL Hubbard, ... American Journal of Physiology-Cell Physiology 283 (3), C927-C940, 2002 | 75 | 2002 |