COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status T Thomas, D Stefanoni, JA Reisz, T Nemkov, L Bertolone, RO Francis, ... JCI insight 5 (14), 2020 | 486 | 2020 |
Inhibition of amino acid metabolism selectively targets human leukemia stem cells CL Jones, BM Stevens, A D'Alessandro, JA Reisz, R Culp-Hill, T Nemkov, ... Cancer cell 34 (5), 724-740. e4, 2018 | 465 | 2018 |
OLT1177, a β-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation C Marchetti, B Swartzwelter, F Gamboni, CP Neff, K Richter, T Azam, ... Proceedings of the National Academy of Sciences 115 (7), E1530-E1539, 2018 | 397 | 2018 |
Monocytic subclones confer resistance to venetoclax-based therapy in patients with acute myeloid leukemia S Pei, DA Pollyea, A Gustafson, BM Stevens, M Minhajuddin, R Fu, ... Cancer discovery 10 (4), 536-551, 2020 | 326 | 2020 |
Evidence of structural protein damage and membrane lipid remodeling in red blood cells from COVID-19 patients T Thomas, D Stefanoni, M Dzieciatkowska, A Issaian, T Nemkov, RC Hill, ... Journal of proteome research 19 (11), 4455-4469, 2020 | 266 | 2020 |
A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer NC D'Amato, TJ Rogers, MA Gordon, LI Greene, DR Cochrane, ... Cancer research 75 (21), 4651-4664, 2015 | 262 | 2015 |
TNF-α–driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging P Davizon-Castillo, B McMahon, S Aguila, D Bark, K Ashworth, A Allawzi, ... Blood, The Journal of the American Society of Hematology 134 (9), 727-740, 2019 | 231 | 2019 |
A three‐minute method for high‐throughput quantitative metabolomics and quantitative tracing experiments of central carbon and nitrogen pathways T Nemkov, KC Hansen, A D'Alessandro Rapid Communications in Mass Spectrometry 31 (8), 663-673, 2017 | 227 | 2017 |
High-throughput metabolomics: isocratic and gradient mass spectrometry-based methods T Nemkov, JA Reisz, S Gehrke, KC Hansen, A D’Alessandro High-Throughput Metabolomics: Methods and Protocols, 13-26, 2019 | 199 | 2019 |
Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells JA Reisz, MJ Wither, M Dzieciatkowska, T Nemkov, A Issaian, T Yoshida, ... Blood, The Journal of the American Society of Hematology 128 (12), e32-e42, 2016 | 196 | 2016 |
Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia K Sun, Y Zhang, A D’Alessandro, T Nemkov, A Song, H Wu, H Liu, ... Nature communications 7 (1), 12086, 2016 | 194 | 2016 |
Three-minute method for amino acid analysis by UHPLC and high-resolution quadrupole orbitrap mass spectrometry T Nemkov, A D’Alessandro, KC Hansen Amino acids 47, 2345-2357, 2015 | 169 | 2015 |
Nicotinamide metabolism mediates resistance to venetoclax in relapsed acute myeloid leukemia stem cells CL Jones, BM Stevens, DA Pollyea, R Culp-Hill, JA Reisz, T Nemkov, ... Cell stem cell 27 (5), 748-764. e4, 2020 | 160 | 2020 |
Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression O Maller, AP Drain, AS Barrett, S Borgquist, B Ruffell, I Zakharevich, ... Nature materials 20 (4), 548-559, 2021 | 159 | 2021 |
Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge K Nohara, V Mallampalli, T Nemkov, M Wirianto, J Yang, Y Ye, Y Sun, ... Nature communications 10 (1), 3923, 2019 | 148 | 2019 |
Targeting glutamine metabolism and redox state for leukemia therapy MA Gregory, T Nemkov, HJ Park, V Zaberezhnyy, S Gehrke, B Adane, ... Clinical Cancer Research 25 (13), 4079-4090, 2019 | 143 | 2019 |
Intracellular localization of diacylglycerols and sphingolipids influences insulin sensitivity and mitochondrial function in human skeletal muscle L Perreault, SA Newsom, A Strauss, A Kerege, DE Kahn, KA Harrison, ... JCI insight 3 (3), 2018 | 140 | 2018 |
Beneficial role of erythrocyte adenosine A2B receptor–Mediated AMP-activated Protein Kinase activation in high-altitude hypoxia H Liu, Y Zhang, H Wu, A D’Alessandro, GG Yegutkin, A Song, K Sun, J Li, ... Circulation 134 (5), 405-421, 2016 | 134 | 2016 |
Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage T Nemkov, K Sun, JA Reisz, A Song, T Yoshida, A Dunham, MJ Wither, ... haematologica 103 (2), 361, 2018 | 130 | 2018 |
Routine storage of red blood cell (RBC) units in additive solution‐3: a comprehensive investigation of the RBC metabolome A D'Alessandro, T Nemkov, M Kelher, FB West, RK Schwindt, A Banerjee, ... Transfusion 55 (6), 1155-1168, 2015 | 121 | 2015 |