Single-cell transcriptomic analysis of tumor-derived fibroblasts and normal tissue-resident fibroblasts reveals fibroblast heterogeneity in breast cancer A Sebastian, NR Hum, KA Martin, SF Gilmore, I Peran, SW Byers, ... Cancers 12 (5), 1307, 2020 | 211 | 2020 |
Sclerostin antibody treatment improves fracture outcomes in a Type I diabetic mouse model CS Yee, LQ Xie, S Hatsell, N Hum, D Murugesh, AN Economides, ... Bone 82, 122-134, 2016 | 85 | 2016 |
Cadherin 11 promotes immunosuppression and extracellular matrix deposition to support growth of pancreatic tumors and resistance to gemcitabine in mice I Peran, S Dakshanamurthy, MD McCoy, A Mavropoulos, B Allo, ... Gastroenterology 160 (4), 1359-1372. e13, 2021 | 68 | 2021 |
Single-cell RNA-seq reveals transcriptomic heterogeneity and post-traumatic osteoarthritis-associated early molecular changes in mouse articular chondrocytes A Sebastian, JL McCool, NR Hum, DK Murugesh, SP Wilson, ... Cells 10 (6), 1462, 2021 | 65 | 2021 |
SOST/Sclerostin improves posttraumatic osteoarthritis and inhibits MMP2/3 expression after injury JC Chang, BA Christiansen, DK Murugesh, A Sebastian, NR Hum, ... Journal of Bone and Mineral Research 33 (6), 1105-1113, 2018 | 64 | 2018 |
Conditional Deletion of Sost in MSC‐Derived Lineages Identifies Specific Cell‐Type Contributions to Bone Mass and B‐Cell Development CS Yee, JO Manilay, JC Chang, NR Hum, DK Murugesh, J Bajwa, ... Journal of Bone and Mineral Research 33 (10), 1748-1759, 2018 | 50 | 2018 |
Osteogenic preconditioning in perfusion bioreactors improves vascularization and bone formation by human bone marrow aspirates JN Harvestine, T Gonzalez-Fernandez, A Sebastian, NR Hum, ... Science advances 6 (7), eaay2387, 2020 | 43 | 2020 |
Electric fields at breast cancer and cancer cell collective galvanotaxis K Zhu, NR Hum, B Reid, Q Sun, GG Loots, M Zhao Scientific reports 10 (1), 8712, 2020 | 42 | 2020 |
Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts A Sebastian, NR Hum, DK Murugesh, S Hatsell, AN Economides, ... PLoS One 12 (11), e0188264, 2017 | 42 | 2017 |
LPS‐induced inflammation prior to injury exacerbates the development of post‐traumatic osteoarthritis in mice ME Mendez, A Sebastian, DK Murugesh, NR Hum, JL McCool, AW Hsia, ... Journal of Bone and Mineral Research 35 (11), 2229-2241, 2020 | 41 | 2020 |
Functional and transcriptional characterization of complex neuronal co-cultures HA Enright, D Lam, A Sebastian, AP Sales, J Cadena, NR Hum, ... Scientific reports 10 (1), 11007, 2020 | 40 | 2020 |
Global gene expression analysis identifies age-related differences in knee joint transcriptome during the development of post-traumatic osteoarthritis in mice A Sebastian, DK Murugesh, ME Mendez, NR Hum, ND Rios-Arce, ... International journal of molecular sciences 21 (1), 364, 2020 | 40 | 2020 |
Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells NM Collette, CS Yee, NR Hum, DK Murugesh, BA Christiansen, LQ Xie, ... Bone 88, 20-30, 2016 | 40 | 2016 |
Cancer–Osteoblast Interaction Reduces Sost Expression in Osteoblasts and Up-Regulates lncRNA MALAT1 in Prostate Cancer A Sebastian, NR Hum, BD Hudson, GG Loots Microarrays 4 (4), 503-519, 2015 | 40 | 2015 |
Single-cell RNA-Seq reveals changes in immune landscape in post-traumatic osteoarthritis A Sebastian, NR Hum, JL McCool, SP Wilson, DK Murugesh, KA Martin, ... Frontiers in immunology 13, 938075, 2022 | 39 | 2022 |
SOST inhibits prostate cancer invasion BD Hudson, NR Hum, CB Thomas, A Kohlgruber, A Sebastian, ... PLoS One 10 (11), e0142058, 2015 | 39 | 2015 |
Comparative molecular analysis of cancer behavior cultured in vitro, in vivo, and ex vivo NR Hum, A Sebastian, SF Gilmore, W He, KA Martin, A Hinckley, ... Cancers 12 (3), 690, 2020 | 29 | 2020 |
Maternal exposure to an environmentally relevant dose of triclocarban results in perinatal exposure and potential alterations in offspring development in the mouse model HA Enright, MJS Falso, MA Malfatti, V Lao, EA Kuhn, N Hum, Y Shi, ... PloS one 12 (8), e0181996, 2017 | 28 | 2017 |
MAVS mediates a protective immune response in the brain to Rift Valley fever virus NR Hum, FA Bourguet, A Sebastian, D Lam, AM Phillips, KR Sanchez, ... PLoS pathogens 18 (5), e1010231, 2022 | 25 | 2022 |
Manipulation of the gut microbiome alters acetaminophen biodisposition in mice MA Malfatti, EA Kuhn, DK Murugesh, ME Mendez, N Hum, JB Thissen, ... Scientific reports 10 (1), 4571, 2020 | 24 | 2020 |