Sustainable replication and coevolution of cooperative RNAs in an artificial cell-like system R Mizuuchi, N Ichihashi Nature Ecology & Evolution 2 (10), 1654-1660, 2018 | 53 | 2018 |
Evolutionary transition from a single RNA replicator to a multiple replicator network R Mizuuchi, T Furubayashi, N Ichihashi Nature Communications 13 (1), 1460, 2022 | 51 | 2022 |
Emergence and diversification of a host-parasite RNA ecosystem through Darwinian evolution T Furubayashi, K Ueda, Y Bansho, D Motooka, S Nakamura, R Mizuuchi, ... Elife 9, e56038, 2020 | 43 | 2020 |
Mineral surfaces select for longer RNA molecules R Mizuuchi, A Blokhuis, L Vincent, P Nghe, N Lehman, D Baum Chemical communications 55 (14), 2090-2093, 2019 | 29 | 2019 |
Primitive compartmentalization for the sustainable replication of genetic molecules R Mizuuchi, N Ichihashi Life 11 (3), 191, 2021 | 26 | 2021 |
Spontaneous advent of genetic diversity in RNA populations through multiple recombination mechanisms BA Smail, BE Clifton, R Mizuuchi, N Lehman Rna 25 (4), 453-464, 2019 | 24 | 2019 |
Translation-coupled RNA replication and parasitic replicators in membrane-free compartments R Mizuuchi, N Ichihashi Chemical Communications 56 (87), 13453-13456, 2020 | 22 | 2020 |
Adaptive evolution of an artificial RNA genome to a reduced ribosome environment R Mizuuchi, N Ichihashi, K Usui, Y Kazuta, T Yomo ACS Synthetic Biology 4 (3), 292-298, 2015 | 20 | 2015 |
Limited sequence diversity within a population supports prebiotic RNA reproduction R Mizuuchi, N Lehman Life 9 (1), 20, 2019 | 13 | 2019 |
Simple rules for construction of a geometric nest structure by pufferfish R Mizuuchi, H Kawase, H Shin, D Iwai, S Kondo Scientific reports 8 (1), 12366, 2018 | 12 | 2018 |
PURE mRNA display and cDNA display provide rapid detection of core epitope motif via high‐throughput sequencing SG Reyes, Y Kuruma, M Fujimi, M Yamazaki, S Eto, S Nishikawa, ... Biotechnology and bioengineering 118 (4), 1702-1715, 2021 | 11 | 2021 |
Discovery of an Earliest-Stage “Mystery Circle” and Development of the Structure Constructed by Pufferfish, Torquigener albomaculosus (Pisces: Tetraodontidae) H Kawase, R Mizuuchi, H Shin, Y Kitajima, K Hosoda, M Shimizu, D Iwai, ... Fishes 2 (3), 14, 2017 | 11 | 2017 |
In vitro evolution of phi29 DNA polymerases through compartmentalized gene expression and rolling-circle replication Y Sakatani, R Mizuuchi, N Ichihashi Protein Engineering, Design and Selection 32 (11), 481-487, 2019 | 10 | 2019 |
Adaptation and diversification of an RNA replication system under initiation‐or termination‐impaired translational conditions R Mizuuchi, N Ichihashi, T Yomo ChemBioChem 17 (13), 1229-1232, 2016 | 10 | 2016 |
Structural transition of replicable RNAs during in vitro evolution with Qβ replicase R Mizuuchi, K Usui, N Ichihashi RNA 26 (1), 83-90, 2020 | 7 | 2020 |
A fusion method to develop an expanded artificial genomic RNA replicable by Qβ replicase K Ueda, R Mizuuchi, F Matsuda, N Ichihashi ChemBioChem 20 (18), 2331-2335, 2019 | 5 | 2019 |
Emergence of linkage between cooperative RNA replicators encoding replication and metabolic enzymes through experimental evolution K Ueda, R Mizuuchi, N Ichihashi PLoS Genetics 19 (8), e1010471, 2023 | 3 | 2023 |
Minimal RNA self-reproduction discovered from a random pool of oligomers R Mizuuchi, N Ichihashi Chemical Science 14 (28), 7656-7664, 2023 | 3 | 2023 |
Plausible pathway for a host-parasite molecular replication network to increase its complexity through Darwinian evolution R Kamiura, R Mizuuchi, N Ichihashi PLOS Computational Biology 18 (12), e1010709, 2022 | 3 | 2022 |
Relaxed substrate specificity in Qβ replicase through long-term in vitro evolution K Yukawa, R Mizuuchi, N Ichihashi Life 12 (1), 32, 2021 | 3 | 2021 |