Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants LAJ O'Neill, C Greene Journal of leukocyte biology 63 (6), 650-657, 1998 | 734 | 1998 |
Innate immunity in cystic fibrosis lung disease D Hartl, A Gaggar, E Bruscia, A Hector, V Marcos, A Jung, C Greene, ... Journal of Cystic Fibrosis 11 (5), 363-382, 2012 | 309 | 2012 |
Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4 JM Devaney, CM Greene, CC Taggart, TP Carroll, SJ O’Neill, ... FEBS letters 544 (1-3), 129-132, 2003 | 292 | 2003 |
TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells CM Greene, TP Carroll, SGJ Smith, CC Taggart, J Devaney, S Griffin, ... The Journal of Immunology 174 (3), 1638-1646, 2005 | 290 | 2005 |
Association of IL-10 polymorphism with severity of illness in community acquired pneumonia PM Gallagher, G Lowe, T Fitzgerald, A Bella, CM Greene, NG McElvaney, ... Thorax 58 (2), 154-156, 2003 | 288 | 2003 |
Secretory leucoprotease inhibitor binds to NF-κB binding sites in monocytes and inhibits p65 binding CC Taggart, SA Cryan, S Weldon, A Gibbons, CM Greene, E Kelly, ... The Journal of experimental medicine 202 (12), 1659-1668, 2005 | 284 | 2005 |
α1-Antitrypsin deficiency CM Greene, SJ Marciniak, J Teckman, I Ferrarotti, ML Brantly, DA Lomas, ... Nature reviews Disease primers 2 (1), 1-17, 2016 | 279 | 2016 |
Inactivation of human β-defensins 2 and 3 by elastolytic cathepsins CC Taggart, CM Greene, SG Smith, RL Levine, PB McCray, S O’Neill, ... The Journal of Immunology 171 (2), 931-937, 2003 | 259 | 2003 |
miR-126 is downregulated in cystic fibrosis airway epithelial cells and regulates TOM1 expression IK Oglesby, IM Bray, SH Chotirmall, RL Stallings, SJ O’Neill, ... The journal of immunology 184 (4), 1702-1709, 2010 | 235 | 2010 |
Activation of endoplasmic reticulum-specific stress responses associated with the conformational disease Z α1-antitrypsin deficiency MW Lawless, CM Greene, A Mulgrew, CC Taggart, SJ O’Neill, ... The Journal of Immunology 172 (9), 5722-5726, 2004 | 222 | 2004 |
Cathepsin B, L, and S cleave and inactivate secretory leucoprotease inhibitor CC Taggart, GJ Lowe, CM Greene, AT Mulgrew, SJ O'Neill, RL Levine, ... Journal of biological chemistry 276 (36), 33345-33352, 2001 | 218 | 2001 |
Effect of estrogen on pseudomonas mucoidy and exacerbations in cystic fibrosis SH Chotirmall, SG Smith, C Gunaratnam, S Cosgrove, BD Dimitrov, ... New England journal of medicine 366 (21), 1978-1986, 2012 | 214 | 2012 |
Interleukin-8 up-regulation by neutrophil elastase is mediated by MyD88/IRAK/TRAF-6 in human bronchial epithelium DE Walsh, CM Greene, TP Carroll, CC Taggart, PM Gallagher, SJ O'Neill, ... Journal of Biological Chemistry 276 (38), 35494-35499, 2001 | 209 | 2001 |
Z α1-antitrypsin polymerizes in the lung and acts as a neutrophil chemoattractant AT Mulgrew, CC Taggart, MW Lawless, CM Greene, ML Brantly, ... Chest 125 (5), 1952-1957, 2004 | 204 | 2004 |
MicroRNAs in inflammatory lung disease-master regulators or target practice? IK Oglesby, NG McElvaney, CM Greene Respiratory research 11, 1-13, 2010 | 202 | 2010 |
Loss of microbicidal activity and increased formation of biofilm due to decreased lactoferrin activity in patients with cystic fibrosis MP Rogan, CC Taggart, CM Greene, PG Murphy, SJ O'Neill, ... The Journal of infectious diseases 190 (7), 1245-1253, 2004 | 202 | 2004 |
Proteases and antiproteases in chronic neutrophilic lung disease–relevance to drug discovery CM Greene, NG McElvaney British journal of pharmacology 158 (4), 1048-1058, 2009 | 197 | 2009 |
Antimicrobial proteins and polypeptides in pulmonary innate defence MP Rogan, P Geraghty, CM Greene, SJ O'Neill, CC Taggart, ... Respiratory research 7, 1-11, 2006 | 195 | 2006 |
Clarification of the Risk of Chronic Obstructive Pulmonary Disease in α1-Antitrypsin Deficiency PiMZ Heterozygotes K Molloy, CP Hersh, VB Morris, TP Carroll, CA O’Connor, JA Lasky-Su, ... American journal of respiratory and critical care medicine 189 (4), 419-427, 2014 | 185 | 2014 |
Secretory leucoprotease inhibitor prevents lipopolysaccharide-induced IκBα degradation without affecting phosphorylation or ubiquitination CC Taggart, CM Greene, NG McElvaney, S O'Neill Journal of Biological Chemistry 277 (37), 33648-33653, 2002 | 181 | 2002 |