关注
Douglas Barker
Douglas Barker
Center for Genomic Medicine, Massachusetts General Hospital
在 mgh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
De novo mutations in schizophrenia implicate synaptic networks
M Fromer, AJ Pocklington, DH Kavanagh, HJ Williams, S Dwyer, ...
Nature 506 (7487), 179-184, 2014
18502014
Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection
DD Barker, AJ Berk
Virology 156 (1), 107-121, 1987
5061987
CAG repeat not polyglutamine length determines timing of Huntington’s disease onset
JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ...
Cell 178 (4), 887-900. e14, 2019
3322019
Pumilio is essential for function but not for distribution of the Drosophila abdominal determinant Nanos.
DD Barker, C Wang, J Moore, LK Dickinson, R Lehmann
Genes & development 6 (12a), 2312-2326, 1992
2721992
Phase I study of GSK461364, a specific and competitive Polo-like kinase 1 inhibitor, in patients with advanced solid malignancies
D Olmos, D Barker, R Sharma, AT Brunetto, TA Yap, AB Taegtmeyer, ...
Clinical cancer research 17 (10), 3420-3430, 2011
2002011
Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities
JM Madison, F Zhou, A Nigam, A Hussain, DD Barker, R Nehme, ...
Molecular psychiatry 20 (6), 703-717, 2015
1922015
Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies
T Dvash, Y Mayshar, H Darr, M McElhaney, D Barker, O Yanuka, ...
Human Reproduction 19 (12), 2875-2883, 2004
1882004
Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder
S Bavamian, N Mellios, J Lalonde, DM Fass, J Wang, SD Sheridan, ...
Molecular psychiatry 20 (5), 573-584, 2015
1782015
A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests
FA Schroeder, MC Lewis, DM Fass, FF Wagner, YL Zhang, KM Hennig, ...
PloS one 8 (8), e71323, 2013
1582013
Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity
DM Fass, SA Reis, B Ghosh, KM Hennig, NF Joseph, WN Zhao, ...
Neuropharmacology 64, 81-96, 2013
1142013
An unbiased approach to identify endogenous substrates of “histone” deacetylase 8
DE Olson, ND Udeshi, NA Wolfson, CA Pitcairn, ED Sullivan, JD Jaffe, ...
ACS chemical biology 9 (10), 2210-2216, 2014
1072014
Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder
EH Rueckert, D Barker, D Ruderfer, SE Bergen, C O'Dushlaine, CJ Luce, ...
Molecular psychiatry 18 (8), 922-929, 2013
952013
Discovery of potent and highly selective inhibitors of GSK3b
WF An, AR Germain, JA Bishop, PP Nag, S Metkar, J Ketterman, M Walk, ...
Probe Reports from the NIH Molecular Libraries Program [Internet], 2014
672014
Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia
E Rees, G Kirov, JT Walters, AL Richards, D Howrigan, DH Kavanagh, ...
Translational psychiatry 5 (7), e607-e607, 2015
422015
Retrovirus-induced insertional mutagenesis: mechanism of collagen mutation in Mov13 mice
DD Barker, H Wu, S Hartung, M Breindl, R Jaenisch
Molecular and cellular biology 11 (10), 5154-5163, 1991
391991
Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s disease
N Ellis, A Tee, B McAllister, T Massey, D McLauchlan, T Stone, K Correia, ...
Biological Psychiatry 87 (9), 857-865, 2020
362020
Human-mouse interspecies collagen I heterotrimer is functional during embryonic development of Mov13 mutant mouse embryos
H Wu, JF Bateman, A Schnieke, A Sharpe, D Barker, T Mascara, D Eyre, ...
Molecular and cellular biology 10 (4), 1452-1460, 1990
331990
Expression of axotomy-inducible and apoptosis-related genes in sensory nerves of rats with experimental diabetes
RC Burnand, SA Price, M McElhaney, D Barker, DR Tomlinson
Molecular brain research 132 (2), 235-240, 2004
312004
Mutations causing Lopes-Maciel-Rodan syndrome are huntingtin hypomorphs
R Jung, Y Lee, D Barker, K Correia, B Shin, J Loupe, RL Collins, ...
Human Molecular Genetics 30 (3-4), 135-148, 2021
252021
Isolation and expression of PASK, a serine/threonine kinase, during rat embryonic development, with special emphasis on the pancreas
N Miao, B Fung, R Sanchez, J Lydon, D Barker, K Pang
Journal of Histochemistry & Cytochemistry 48 (10), 1391-1400, 2000
232000
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