De novo mutations in schizophrenia implicate synaptic networks M Fromer, AJ Pocklington, DH Kavanagh, HJ Williams, S Dwyer, ... Nature 506 (7487), 179-184, 2014 | 1850 | 2014 |
Adenovirus proteins from both E1B reading frames are required for transformation of rodent cells by viral infection and DNA transfection DD Barker, AJ Berk Virology 156 (1), 107-121, 1987 | 506 | 1987 |
CAG repeat not polyglutamine length determines timing of Huntington’s disease onset JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ... Cell 178 (4), 887-900. e14, 2019 | 332 | 2019 |
Pumilio is essential for function but not for distribution of the Drosophila abdominal determinant Nanos. DD Barker, C Wang, J Moore, LK Dickinson, R Lehmann Genes & development 6 (12a), 2312-2326, 1992 | 272 | 1992 |
Phase I study of GSK461364, a specific and competitive Polo-like kinase 1 inhibitor, in patients with advanced solid malignancies D Olmos, D Barker, R Sharma, AT Brunetto, TA Yap, AB Taegtmeyer, ... Clinical cancer research 17 (10), 3420-3430, 2011 | 200 | 2011 |
Characterization of bipolar disorder patient-specific induced pluripotent stem cells from a family reveals neurodevelopmental and mRNA expression abnormalities JM Madison, F Zhou, A Nigam, A Hussain, DD Barker, R Nehme, ... Molecular psychiatry 20 (6), 703-717, 2015 | 192 | 2015 |
Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies T Dvash, Y Mayshar, H Darr, M McElhaney, D Barker, O Yanuka, ... Human Reproduction 19 (12), 2875-2883, 2004 | 188 | 2004 |
Dysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder S Bavamian, N Mellios, J Lalonde, DM Fass, J Wang, SD Sheridan, ... Molecular psychiatry 20 (5), 573-584, 2015 | 178 | 2015 |
A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests FA Schroeder, MC Lewis, DM Fass, FF Wagner, YL Zhang, KM Hennig, ... PloS one 8 (8), e71323, 2013 | 158 | 2013 |
Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity DM Fass, SA Reis, B Ghosh, KM Hennig, NF Joseph, WN Zhao, ... Neuropharmacology 64, 81-96, 2013 | 114 | 2013 |
An unbiased approach to identify endogenous substrates of “histone” deacetylase 8 DE Olson, ND Udeshi, NA Wolfson, CA Pitcairn, ED Sullivan, JD Jaffe, ... ACS chemical biology 9 (10), 2210-2216, 2014 | 107 | 2014 |
Cis-acting regulation of brain-specific ANK3 gene expression by a genetic variant associated with bipolar disorder EH Rueckert, D Barker, D Ruderfer, SE Bergen, C O'Dushlaine, CJ Luce, ... Molecular psychiatry 18 (8), 922-929, 2013 | 95 | 2013 |
Discovery of potent and highly selective inhibitors of GSK3b WF An, AR Germain, JA Bishop, PP Nag, S Metkar, J Ketterman, M Walk, ... Probe Reports from the NIH Molecular Libraries Program [Internet], 2014 | 67 | 2014 |
Analysis of exome sequence in 604 trios for recessive genotypes in schizophrenia E Rees, G Kirov, JT Walters, AL Richards, D Howrigan, DH Kavanagh, ... Translational psychiatry 5 (7), e607-e607, 2015 | 42 | 2015 |
Retrovirus-induced insertional mutagenesis: mechanism of collagen mutation in Mov13 mice DD Barker, H Wu, S Hartung, M Breindl, R Jaenisch Molecular and cellular biology 11 (10), 5154-5163, 1991 | 39 | 1991 |
Genetic risk underlying psychiatric and cognitive symptoms in Huntington’s disease N Ellis, A Tee, B McAllister, T Massey, D McLauchlan, T Stone, K Correia, ... Biological Psychiatry 87 (9), 857-865, 2020 | 36 | 2020 |
Human-mouse interspecies collagen I heterotrimer is functional during embryonic development of Mov13 mutant mouse embryos H Wu, JF Bateman, A Schnieke, A Sharpe, D Barker, T Mascara, D Eyre, ... Molecular and cellular biology 10 (4), 1452-1460, 1990 | 33 | 1990 |
Expression of axotomy-inducible and apoptosis-related genes in sensory nerves of rats with experimental diabetes RC Burnand, SA Price, M McElhaney, D Barker, DR Tomlinson Molecular brain research 132 (2), 235-240, 2004 | 31 | 2004 |
Mutations causing Lopes-Maciel-Rodan syndrome are huntingtin hypomorphs R Jung, Y Lee, D Barker, K Correia, B Shin, J Loupe, RL Collins, ... Human Molecular Genetics 30 (3-4), 135-148, 2021 | 25 | 2021 |
Isolation and expression of PASK, a serine/threonine kinase, during rat embryonic development, with special emphasis on the pancreas N Miao, B Fung, R Sanchez, J Lydon, D Barker, K Pang Journal of Histochemistry & Cytochemistry 48 (10), 1391-1400, 2000 | 23 | 2000 |