| Site-specific DICER and DROSHA RNA products control the DNA-damage response S Francia, F Michelini, A Saxena, D Tang, M De Hoon, V Anelli, M Mione, ... Nature 488 (7410), 231-235, 2012 | 585 | 2012 |
| Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks F Michelini, S Pitchiaya, V Vitelli, S Sharma, U Gioia, F Pessina, M Cabrini, ... Nature cell biology 19 (12), 1400-1411, 2017 | 350 | 2017 |
| DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors S Francia, M Cabrini, V Matti, A Oldani, F d'Adda di Fagagna Journal of cell science 129 (7), 1468-1476, 2016 | 154 | 2016 |
| A damaged genome’s transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks F Iannelli, A Galbiati, I Capozzo, Q Nguyen, B Magnuson, F Michelini, ... Nature communications 8 (1), 15656, 2017 | 104 | 2017 |
| From “cellular” RNA to “smart” RNA: multiple roles of RNA in genome stability and beyond F Michelini, AP Jalihal, S Francia, C Meers, ZT Neeb, F Rossiello, U Gioia, ... Chemical reviews 118 (8), 4365-4403, 2018 | 83 | 2018 |
| Pharmacological boost of DNA damage response and repair by enhanced biogenesis of DNA damage response RNAs U Gioia, S Francia, M Cabrini, S Brambillasca, F Michelini, ... Scientific reports 9 (1), 6460, 2019 | 70 | 2019 |
| Telomere and telomerase modulation by the mammalian Rad9/Rad1/Hus1 DNA-damage-checkpoint complex S Francia, RS Weiss, MP Hande, R Freire, FA di Fagagna Current biology 16 (15), 1551-1558, 2006 | 67 | 2006 |
| DNA damage triggers a new phase in neurodegeneration F Pessina, U Gioia, O Brandi, S Farina, M Ceccon, S Francia, ... Trends in Genetics 37 (4), 337-354, 2021 | 60 | 2021 |
| MRE11-RAD50-NBS1 complex is sufficient to promote transcription by RNA polymerase II at double-strand breaks by melting DNA ends S Sharma, R Anand, X Zhang, S Francia, F Michelini, A Galbiati, ... Cell reports 34 (1), 2021 | 57 | 2021 |
| Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53 I Venkata Narayanan, MT Paulsen, K Bedi, N Berg, EA Ljungman, ... Scientific Reports 7 (1), 43598, 2017 | 56 | 2017 |
| Express or repress? The transcriptional dilemma of damaged chromatin I Capozzo, F Iannelli, S Francia, F d'Adda di Fagagna The FEBS journal 284 (14), 2133-2147, 2017 | 39 | 2017 |
| DROSHA RNA products control the DNA-damage response S Francia, F Michelini, A Saxena, D Tang, M De Hoon, V Anelli, M Mione, ... Nature 488 (7410), 231-235, 2012 | 36 | 2012 |
| Non-coding RNA: sequence-specific guide for chromatin modification and DNA damage signaling S Francia Frontiers in genetics 6, 153021, 2015 | 29 | 2015 |
| Post-translational modifications modulate proteinopathies of TDP-43, FUS and hnRNP-A/B in amyotrophic lateral sclerosis S Farina, F Esposito, M Battistoni, G Biamonti, S Francia Frontiers in Molecular Biosciences 8, 693325, 2021 | 28 | 2021 |
| A missense MT-ND5 mutation in differentiated Parkinson Disease cytoplasmic hybrid induces ROS-dependent DNA Damage Response amplified by DROSHA D Pignataro, S Francia, F Zanetta, G Brenna, S Brandini, A Olivieri, ... Scientific reports 7 (1), 9528, 2017 | 24 | 2017 |
| Need telomere maintenance? Call 911 S Francia, RS Weiss, F d'Adda di Fagagna Cell Division 2, 1-6, 2007 | 16 | 2007 |
| DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end joining M Cabrini, M Roncador, A Galbiati, L Cipolla, A Maffia, F Iannelli, ... Journal of Cell Science 134 (6), jcs249706, 2021 | 13 | 2021 |
| RNase A treatment and reconstitution with DNA damage response RNA in living cells as a tool to study the role of non-coding RNA in the formation of DNA damage response foci F Michelini, F Rossiello, F d’Adda di Fagagna, S Francia Nature Protocols 14 (5), 1489-1508, 2019 | 8 | 2019 |
| d’Adda di Fagagna F S Francia, F Michelini, A Saxena, D Tang, M de Hoon, V Anelli, M Mione, ... Nature 488 (7410), 231, 2012 | 5 | 2012 |
| TGS1 impacts snRNA 3′-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration L Chen, CM Roake, P Maccallini, F Bavasso, R Dehghannasiri, ... Nucleic Acids Research 50 (21), 12400-12424, 2022 | 4 | 2022 |
Flavia MicheliniAssociate Director, Translational Medicine at AstraZeneca在 astrazeneca.com 的电子邮件经过验证
