| Polyvalent interactions in biological systems: implications for design and use of multivalent ligands and inhibitors M Mammen, SK Choi, GM Whitesides Angewandte Chemie International Edition 37 (20), 2754-2794, 1998 | 5176 | 1998 |
| Noncovalent synthesis: using physical-organic chemistry to make aggregates GM Whitesides, EE Simanek, JP Mathias, CT Seto, D Chin, M Mammen, ... Accounts of Chemical Research 28 (1), 37-44, 1995 | 1326 | 1995 |
| Polyvalente Wechselwirkungen in biologischen Systemen: Auswirkungen auf das Design und die Verwendung multivalenter Liganden und Inhibitoren M Mammen, SK Choi, GM Whitesides Angewandte Chemie 110 (20), 2908-2953, 1998 | 560 | 1998 |
| Effective inhibitors of hemagglutination by influenza virus synthesized from polymers having active ester groups. Insight into mechanism of inhibition M Mammen, G Dahmann, GM Whitesides Journal of medicinal chemistry 38 (21), 4179-4190, 1995 | 515 | 1995 |
| Estimating the Entropic Cost of Self-Assembly of Multiparticle Hydrogen-Bonded Aggregates Based on the Cyanuric Acid⊙ Melamine Lattice M Mammen, EI Shakhnovich, JM Deutch, GM Whitesides The Journal of Organic Chemistry 63 (12), 3821-3830, 1998 | 474 | 1998 |
| Polyacrylamides bearing pendant α-sialoside groups strongly inhibit agglutination of erythrocytes by influenza virus: the strong inhibition reflects enhanced binding through … GB Sigal, M Mammen, G Dahmann, GM Whitesides Journal of the American Chemical Society 118 (16), 3789-3800, 1996 | 473 | 1996 |
| Generation and in Situ Evaluation of Libraries of Poly(acrylic acid) Presenting Sialosides as Side Chains as Polyvalent Inhibitors of Influenza-Mediated … SK Choi, M Mammen, GM Whitesides Journal of the American Chemical Society 119 (18), 4103-4111, 1997 | 288 | 1997 |
| Using electrospray ionization FTICR mass spectrometry to study competitive binding of inhibitors to carbonic anhydrase X Cheng, R Chen, JE Bruce, BL Schwartz, GA Anderson, SA Hofstadler, ... Journal of the American Chemical Society 117 (34), 8859-8860, 1995 | 244 | 1995 |
| Telavancin disrupts the functional integrity of the bacterial membrane through targeted interaction with the cell wall precursor lipid II CS Lunde, SR Hartouni, JW Janc, M Mammen, PP Humphrey, BM Benton Antimicrobial agents and chemotherapy 53 (8), 3375-3383, 2009 | 204 | 2009 |
| Biphenyl derivatives M Mammen, S Dunham, A Hughes, TW Lee, C Husfeld, E Stangeland, ... US Patent 7,141,671, 2006 | 176 | 2006 |
| Using a convenient, quantitative model for torsional entropy to establish qualitative trends for molecular processes that restrict conformational freedom M Mammen, EI Shakhnovich, GM Whitesides The Journal of Organic Chemistry 63 (10), 3168-3175, 1998 | 166 | 1998 |
| Muscarinic receptor antagonists J Aggen, JH Griffin, M Mammen, D Marquess, EJ Moran, D Oare US Patent 6,693,202, 2004 | 152 | 2004 |
| Monomeric inhibitors of influenza neuraminidase enhance the hemagglutination inhibition activities of polyacrylamides presenting multiple C-sialoside groups SK Choi, M Mammen, GM Whitesides Chemistry & biology 3 (2), 97-104, 1996 | 119 | 1996 |
| Evaluating electrostatic contributions to binding with the use of protein charge ladders J Gao, M Mammen, GM Whitesides Science 272 (5261), 535-537, 1996 | 116 | 1996 |
| A novel multivalent ligand that bridges the allosteric and orthosteric binding sites of the M2 muscarinic receptor T Steinfeld, M Mammen, JAM Smith, RD Wilson, JR Jasper Molecular pharmacology 72 (2), 291-302, 2007 | 109 | 2007 |
| Library of biphenyl derivatives M Mammen, S Dunham, A Hughes US Patent App. 10/778,290, 2004 | 108 | 2004 |
| Biphenyl derivatives having beta2 adrenergic receptor agonist and muscarinic receptor antagonist activity M Mammen, S Dunham, A Hughes US Patent App. 10/778,649, 2004 | 105 | 2004 |
| Predicting the relative stabilities of multiparticle hydrogen-bonded aggregates based on the number of hydrogen bonds and the number of particles and measuring these … M Mammen, EE Simanek, GM Whitesides Journal of the American Chemical Society 118 (50), 12614-12623, 1996 | 101 | 1996 |
| Therapeutic ureas M Mammen, D Oare US Patent 6,635,764, 2003 | 99 | 2003 |
| Optically controlled collisions of biological objects to evaluate potent polyvalent inhibitors of virus-cell adhesion M Mammen, K Helmerson, R Kishore, SK Choi, WD Phillips, ... Chemistry & biology 3 (9), 757-763, 1996 | 97 | 1996 |
