Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening CY Liao, BA Rikke, TE Johnson, V Diaz, JF Nelson Aging cell 9 (1), 92-95, 2010 | 551 | 2010 |
Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival. FJ Ramos, SC Chen, MG Garelick, DF Dai, CY Liao, KH Schreiber, ... Science Translational Medicine 4 (144), 144ra103, 2012 | 370 | 2012 |
Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice AA Shahmirzadi, D Edgar, CY Liao, YM Hsu, M Lucanic, AA Shahmirzadi, ... Cell metabolism 32 (3), 447-456. e6, 2020 | 254 | 2020 |
Rapamycin‐mediated mTORC 2 inhibition is determined by the relative expression of FK 506‐binding proteins KH Schreiber, D Ortiz, EC Academia, AC Anies, CY Liao, BK Kennedy Aging cell 14 (2), 265-273, 2015 | 181 | 2015 |
A novel rapamycin analog is highly selective for mTORC1 in vivo KH Schreiber, SI Arriola Apelo, D Yu, JA Brinkman, MC Velarde, FA Syed, ... Nature communications 10 (1), 3194, 2019 | 152 | 2019 |
Fat maintenance is a predictor of the murine lifespan response to dietary restriction CY Liao, BA Rikke, TE Johnson, JAL Gelfond, V Diaz, JF Nelson Aging Cell 10 (4), 629-639, 2011 | 140 | 2011 |
MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage P Sousa-Victor, J Neves, W Cedron-Craft, PB Ventura, CY Liao, RR Riley, ... Nature metabolism 1 (2), 276-290, 2019 | 112 | 2019 |
Genetic dissection of dietary restriction in mice supports the metabolic efficiency model of life extension BA Rikke, CY Liao, MB McQueen, JF Nelson, TE Johnson Experimental gerontology 45 (9), 691-701, 2010 | 98 | 2010 |
C. elegans S6K mutants require a creatine-kinase-like effector for lifespan extension PR McQuary, CY Liao, JT Chang, C Kumsta, X She, A Davis, CC Chu, ... Cell reports 14 (9), 2059-2067, 2016 | 57 | 2016 |
SIRT6, oxidative stress, and aging CY Liao, BK Kennedy Cell research 26 (2), 143-144, 2016 | 57 | 2016 |
Mouse models and aging: longevity and progeria CY Liao, BK Kennedy Current topics in developmental biology 109, 249-285, 2014 | 56 | 2014 |
Prothymosin alpha enhances protective immune responses induced by oral DNA vaccination against pseudorabies delivered by Salmonella choleraesuis. CLW Ai-Li Shiau, Yen-Lin Chen, Chen-Yu Liao, Yen-Sung Huang Vaccine 19 (28-29), 3947-3956, 2001 | 56 | 2001 |
Rapamycin reverses metabolic deficits in lamin A/C-deficient mice CY Liao, SS Anderson, NH Chicoine, JR Mayfield, EC Academia, ... Cell reports 17 (10), 2542-2552, 2016 | 55 | 2016 |
Expression of sex-determining genes in human sebaceous glands and their possible role in the pathogenesis of acne ZCC Chen W, Yang CC, Liao CY, Hung CL, Tsai SJ, Chen KF, Sheu HM Journal of the European Academy Dermatology and Venereology 20 (7), 846-852, 2006 | 41 | 2006 |
Genetic variation in responses to dietary restriction—an unbiased tool for hypothesis testing CY Liao, TE Johnson, JF Nelson Experimental gerontology 48 (10), 1025-1029, 2013 | 36 | 2013 |
Higher levels of steroidogenic acute regulatory protein and type I 3beta-hydroxysteroid dehydrogenase in the scalp of men with androgenetic alopecia CCZ Wen-Chieh Chen, Shaw-Jenq Tsai, Chen-Yu Liao, Ren-Yeu Tsai, Yi-Ju Chen ... Journal of Investigative Dermatology 126 (10), 2332-2335, 2006 | 32 | 2006 |
Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness Y Levy, JA Ross, M Niglas, VA Snetkov, S Lynham, CY Liao, ... JCI insight 3 (19), 2018 | 20 | 2018 |
Expression of Sex-Determining Genes in the Scalp of Men with Androgenetic Alopecia ZCC Chen W, Yang CC, Tsai RY, Liao CY, Yen YT, Hung CL, Chen KF, Tsai SJ Dermatology 214 (3), 199-204, 2007 | 19 | 2007 |
The autophagy inducer spermidine protects against metabolic dysfunction during overnutrition CY Liao, OMP Kummert, AM Bair, N Alavi, J Alavi, DM Miller, I Bagga, ... The Journals of Gerontology: Series A 76 (10), 1714-1725, 2021 | 17 | 2021 |
Evidence that S6K1, but not 4E-BP1, mediates skeletal muscle pathology associated with loss of A-type lamins CY Liao, SS Anderson, NH Chicoine, JR Mayfield, BJ Garrett, CS Kwok, ... Cell Discovery 3 (1), 1-15, 2017 | 17 | 2017 |