Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease A Beilina, IN Rudenko, A Kaganovich, L Civiero, H Chau, SK Kalia, ... Proceedings of the National Academy of Sciences 111 (7), 2626-2631, 2014 | 391 | 2014 |
mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex AA Dillman, DN Hauser, JR Gibbs, MA Nalls, MK McCoy, IN Rudenko, ... Nature neuroscience 16 (4), 499-506, 2013 | 150 | 2013 |
Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation G Liu, J Yu, J Ding, C Xie, L Sun, I Rudenko, W Zheng, N Sastry, J Luo, ... The Journal of clinical investigation 124 (7), 3032-3046, 2014 | 134 | 2014 |
The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation IN Rudenko, A Kaganovich, DN Hauser, A Beylina, R Chia, J Ding, ... Biochemical Journal 446 (1), 99-111, 2012 | 131 | 2012 |
Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle E Lobbestael, J Zhao, IN Rudenko, A Beylina, F Gao, J Wetter, M Beullens, ... Biochemical Journal, 2013 | 110 | 2013 |
Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7 R Chia, S Haddock, A Beilina, IN Rudenko, A Mamais, A Kaganovich, Y Li, ... Nature communications 5 (1), 5827, 2014 | 109 | 2014 |
Hexokinase activity is required for recruitment of parkin to depolarized mitochondria MK McCoy, A Kaganovich, IN Rudenko, J Ding, MR Cookson Human molecular genetics 23 (1), 145-156, 2014 | 98 | 2014 |
Is inhibition of kinase activity the only therapeutic strategy for LRRK2-associated Parkinson's disease? IN Rudenko, R Chia, MR Cookson BMC medicine 10, 1-8, 2012 | 77 | 2012 |
Heterogeneity of leucine-rich repeat kinase 2 mutations: genetics, mechanisms and therapeutic implications IN Rudenko, MR Cookson Neurotherapeutics 11 (4), 738-750, 2014 | 66 | 2014 |
Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice L Pellegrini, DN Hauser, Y Li, A Mamais, A Beilina, R Kumaran, A Wetzel, ... Human molecular genetics 27 (18), 3257-3271, 2018 | 61 | 2018 |
The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2 IN Rudenko, A Kaganovich, RG Langston, A Beilina, K Ndukwe, ... Biochemical Journal 474 (9), 1547-1558, 2017 | 40 | 2017 |
The function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research RG Langston, IN Rudenko, MR Cookson Biochemical Journal 473 (3), 221-232, 2016 | 37 | 2016 |
14-3-3 proteins are promising LRRK2 interactors IN Rudenko, MR Cookson Biochem. J 430, e5-e6, 2010 | 29 | 2010 |
Differences in stability, activity and mutation effects between human and mouse leucine-rich repeat kinase 2 RG Langston, IN Rudenko, R Kumaran, DN Hauser, A Kaganovich, ... Neurochemical research 44, 1446-1459, 2019 | 11 | 2019 |
Two molecular motility systems of the frog olfactory cilia VO Samoilov, EV Bigdai, IN Rudenko, VV Bekusova, BA Dudich Biophysics 53 (6), 539-543, 2008 | 5 | 2008 |
Effects of lithium on isolated rat heart mitochondria SM Korotkov, VP Nesterov, IN Rudenko, IV Brailovskaya Doklady. Biochemistry and Biophysics 430 (1), 45, 2010 | 3 | 2010 |
Kinetics of Ca2+, NADH, and oxidized flavoproteins in the frog olfactory lining under the effect of odorants IN Rudenko, EV Bigdaĭ, VO Samoĭlov Biofizika 52 (1), 88, 2007 | 3 | 2007 |