| High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing CD Sago, MP Lokugamage, K Paunovska, DA Vanover, CM Monaco, ... Proceedings of the National Academy of Sciences 115 (42), E9944-E9952, 2018 | 251 | 2018 |
| Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs MP Lokugamage, D Vanover, J Beyersdorf, MZC Hatit, L Rotolo, ... Nature biomedical engineering 5 (9), 1059-1068, 2021 | 225 | 2021 |
| Nanoparticles containing oxidized cholesterol deliver mRNA to the liver microenvironment at clinically relevant doses K Paunovska, AJ Da Silva Sanchez, CD Sago, Z Gan, MP Lokugamage, ... Advanced materials 31 (14), 1807748, 2019 | 154 | 2019 |
| Constrained nanoparticles deliver siRNA and sgRNA to T cells in vivo without targeting ligands MP Lokugamage, CD Sago, Z Gan, BR Krupczak, JE Dahlman Advanced Materials 31 (41), 1902251, 2019 | 118 | 2019 |
| Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery K Paunovska, CJ Gil, MP Lokugamage, CD Sago, M Sato, GN Lando, ... ACS nano 12 (8), 8341-8349, 2018 | 115 | 2018 |
| Nanoparticles that deliver RNA to bone marrow identified by in vivo directed evolution CD Sago, MP Lokugamage, FZ Islam, BR Krupczak, M Sato, JE Dahlman Journal of the American Chemical Society 140 (49), 17095-17105, 2018 | 100 | 2018 |
| Mild innate immune activation overrides efficient nanoparticle‐mediated RNA delivery MP Lokugamage, Z Gan, C Zurla, J Levin, FZ Islam, S Kalathoor, M Sato, ... Advanced materials 32 (1), 1904905, 2020 | 93 | 2020 |
| Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles MZC Hatit, MP Lokugamage, CN Dobrowolski, K Paunovska, H Ni, ... Nature nanotechnology 17 (3), 310-318, 2022 | 72 | 2022 |
| Testing thousands of nanoparticles in vivo using DNA barcodes MP Lokugamage, CD Sago, JE Dahlman Current Opinion in Biomedical Engineering 7, 1-8, 2018 | 70 | 2018 |
| Piperazine-derived lipid nanoparticles deliver mRNA to immune cells in vivo H Ni, MZC Hatit, K Zhao, D Loughrey, MP Lokugamage, HE Peck, AD Cid, ... Nature Communications 13 (1), 4766, 2022 | 65 | 2022 |
| Nanoparticle single-cell multiomic readouts reveal that cell heterogeneity influences lipid nanoparticle-mediated messenger RNA delivery C Dobrowolski, K Paunovska, E Schrader Echeverri, D Loughrey, ... Nature Nanotechnology 17 (8), 871-879, 2022 | 47 | 2022 |
| Nanoparticles containing constrained phospholipids deliver mRNA to liver immune cells in vivo without targeting ligands Z Gan, MP Lokugamage, MZC Hatit, D Loughrey, K Paunovska, M Sato, ... Bioengineering & translational medicine 5 (3), e10161, 2020 | 47 | 2020 |
| Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver CD Sago, MP Lokugamage, D Loughrey, KE Lindsay, R Hincapie, ... Nature biomedical engineering 6 (2), 157-167, 2022 | 45 | 2022 |
| Modifying a commonly expressed endocytic receptor retargets nanoparticles in vivo CD Sago, MP Lokugamage, GN Lando, N Djeddar, NN Shah, C Syed, ... Nano letters 18 (12), 7590-7600, 2018 | 43 | 2018 |
| Cell subtypes within the liver microenvironment differentially interact with lipid nanoparticles CD Sago, BR Krupczak, MP Lokugamage, Z Gan, JE Dahlman Cellular and Molecular Bioengineering 12, 389-397, 2019 | 38 | 2019 |
| Therapeutic RNA delivery for COVID and other diseases C Dobrowolski, K Paunovska, MZC Hatit, MP Lokugamage, JE Dahlman Advanced healthcare materials 10 (15), 2002022, 2021 | 37 | 2021 |
| The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo A Radmand, MP Lokugamage, H Kim, C Dobrowolski, R Zenhausern, ... Nano letters 23 (3), 993-1002, 2023 | 28 | 2023 |
| Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery MZC Hatit, CN Dobrowolski, MP Lokugamage, D Loughrey, H Ni, C Zurla, ... Nature Chemistry 15 (4), 508-515, 2023 | 25 | 2023 |
| High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo SG Huayamares, MP Lokugamage, R Rab, AJDS Sanchez, H Kim, ... Journal of Controlled Release 357, 394-403, 2023 | 24 | 2023 |
| Substituting racemic ionizable lipids with stereopure ionizable lipids can increase mRNA delivery AJDS Sanchez, K Zhao, SG Huayamares, MZC Hatit, MP Lokugamage, ... Journal of Controlled Release 353, 270-277, 2023 | 22 | 2023 |
James E. DahlmanEmory School of Medicine / Georgia Tech在 emory.edu 的电子邮件经过验证
