Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies A Baum, BO Fulton, E Wloga, R Copin, KE Pascal, V Russo, S Giordano, ... Science 369 (6506), 1014-1018, 2020 | 1343 | 2020 |
REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters A Baum, D Ajithdoss, R Copin, A Zhou, K Lanza, N Negron, M Ni, Y Wei, ... Science 370 (6520), 1110-1115, 2020 | 585 | 2020 |
MyD88-dependent activation of B220− CD11b+ LY-6C+ dendritic cells during Brucella melitensis infection R Copin, P De Baetselier, Y Carlier, JJ Letesson, E Muraille The Journal of Immunology 178 (8), 5182-5191, 2007 | 218 | 2007 |
The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies R Copin, A Baum, E Wloga, KE Pascal, S Giordano, BO Fulton, A Zhou, ... Cell 184 (15), 3949-3961. e11, 2021 | 204 | 2021 |
Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets DK Singh, B Singh, SR Ganatra, M Gazi, J Cole, R Thippeshappa, ... Nature microbiology 6 (1), 73-86, 2021 | 186 | 2021 |
M. tuberculosis T cell epitope analysis reveals paucity of antigenic variation and identifies rare variable TB antigens M Coscolla, R Copin, J Sutherland, F Gehre, B de Jong, O Owolabi, ... Cell host & microbe 18 (5), 538-548, 2015 | 138 | 2015 |
In Situ Microscopy Analysis Reveals Local Innate Immune Response Developed around Brucella Infected Cells in Resistant and Susceptible Mice R Copin, MA Vitry, D Hanot Mambres, A Machelart, C De Trez, ... PLoS Pathogens 8 (3), e1002575, 2012 | 107 | 2012 |
Sequence Diversity in the pe_pgrs Genes of Mycobacterium tuberculosis Is Independent of Human T Cell Recognition R Copin, M Coscollá, SN Seiffert, G Bothamley, J Sutherland, G Mbayo, ... MBio 5 (1), 10.1128/mbio. 00960-13, 2014 | 93 | 2014 |
Sequential evolution of virulence and resistance during clonal spread of community-acquired methicillin-resistant Staphylococcus aureus R Copin, WE Sause, Y Fulmer, D Balasubramanian, S Dyzenhaus, ... Proceedings of the National Academy of Sciences 116 (5), 1745-1754, 2019 | 78 | 2019 |
Impact of in vitro evolution on antigenic diversity of Mycobacterium bovis bacillus Calmette-Guerin (BCG) R Copin, M Coscollá, E Efstathiadis, S Gagneux, JD Ernst Vaccine 32 (45), 5998-6004, 2014 | 76 | 2014 |
The purine biosynthesis regulator PurR moonlights as a virulence regulator in Staphylococcus aureus WE Sause, D Balasubramanian, I Irnov, R Copin, MJ Sullivan, ... Proceedings of the National Academy of Sciences 116 (27), 13563-13572, 2019 | 61 | 2019 |
Functional Characterization of the Incomplete Phosphotransferase System (PTS) of the Intracellular Pathogen Brucella melitensis M Dozot, S Poncet, C Nicolas, R Copin, H Bouraoui, A Maze, J Deutscher, ... PLoS One 5 (9), e12679, 2010 | 54 | 2010 |
In vivo biosynthesis of terpene nucleosides provides unique chemical markers of Mycobacterium tuberculosis infection DC Young, E Layre, SJ Pan, A Tapley, J Adamson, C Seshadri, Z Wu, ... Chemistry & biology 22 (4), 516-526, 2015 | 41 | 2015 |
SARS-CoV-2 infection leads to acute infection with dynamic cellular and inflammatory flux in the lung that varies across nonhuman primate species DK Singh, SR Ganatra, B Singh, J Cole, KJ Alfson, E Clemmons, M Gazi, ... BioRxiv, 2020.06. 05.136481, 2020 | 36 | 2020 |
Within host evolution selects for a dominant genotype of Mycobacterium tuberculosis while T cells increase pathogen genetic diversity R Copin, X Wang, E Louie, V Escuyer, M Coscolla, S Gagneux, ... PLoS pathogens 12 (12), e1006111, 2016 | 35 | 2016 |
Intracellular rescuing of a B. melitensis 16M virB mutant by co-infection with a wild type strain C Nijskens, R Copin, X De Bolle, JJ Letesson Microbial pathogenesis 45 (2), 134-141, 2008 | 32 | 2008 |
Structure of the Inmazeb cocktail and resistance to Ebola virus escape V Rayaprolu, BO Fulton, A Rafique, E Arturo, D Williams, C Hariharan, ... Cell host & microbe 31 (2), 260-272. e7, 2023 | 23 | 2023 |
After the deluge: Mining Staphylococcus aureus genomic data for clinical associations and host–pathogen interactions R Copin, B Shopsin, VJ Torres Current opinion in microbiology 41, 43-50, 2018 | 22 | 2018 |
Using quantitative spectrometry to understand the influence of genetics and nutritional perturbations on the virulence potential of Staphylococcus aureus JR Chapman, D Balasubramanian, K Tam, M Askenazi, R Copin, ... Molecular & Cellular Proteomics 16 (4), S15-S28, 2017 | 22 | 2017 |
MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation S Dyzenhaus, MJ Sullivan, B Alburquerque, D Boff, A van de Guchte, ... Cell host & microbe 31 (2), 228-242. e8, 2023 | 20 | 2023 |