The moderately efficient enzyme: evolutionary and physicochemical trends shaping enzyme parameters A Bar-Even, E Noor, Y Savir, W Liebermeister, D Davidi, DS Tawfik, ... Biochemistry 50 (21), 4402-4410, 2011 | 1075 | 2011 |
Condition-Dependent Transcriptome Reveals High-Level Regulatory Architecture in Bacillus subtilis P Nicolas, U Mäder, E Dervyn, T Rochat, A Leduc, N Pigeonneau, ... Science 335 (6072), 1103-1106, 2012 | 983 | 2012 |
A comprehensive library of fluorescent transcriptional reporters for Escherichia coli A Zaslaver, A Bren, M Ronen, S Itzkovitz, I Kikoin, S Shavit, ... Nature methods 3 (8), 623-628, 2006 | 881 | 2006 |
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology MJ Herrgård, N Swainston, P Dobson, WB Dunn, KY Arga, M Arvas, ... Nature biotechnology 26 (10), 1155-1160, 2008 | 679 | 2008 |
Systems biology: a textbook E Klipp, W Liebermeister, C Wierling, A Kowald John Wiley & Sons, 2016 | 617 | 2016 |
Glycolytic strategy as a tradeoff between energy yield and protein cost A Flamholz, E Noor, A Bar-Even, W Liebermeister, R Milo Proceedings of the National Academy of Sciences 110 (24), 10039-10044, 2013 | 573 | 2013 |
Linear modes of gene expression determined by independent component analysis W Liebermeister Bioinformatics 18 (1), 51-60, 2002 | 450 | 2002 |
Visual account of protein investment in cellular functions W Liebermeister, E Noor, A Flamholz, D Davidi, J Bernhardt, R Milo Proceedings of the National Academy of Sciences 111 (23), 8488-8493, 2014 | 337 | 2014 |
Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism JM Buescher, W Liebermeister, M Jules, M Uhr, J Muntel, E Botella, ... Science 335 (6072), 1099-1103, 2012 | 329 | 2012 |
Pathway thermodynamics highlights kinetic obstacles in central metabolism E Noor, A Bar-Even, A Flamholz, E Reznik, W Liebermeister, R Milo PLoS computational biology 10 (2), e1003483, 2014 | 313 | 2014 |
Integrating quantitative proteomics and metabolomics with a genome-scale metabolic network model K Yizhak, T Benyamini, W Liebermeister, E Ruppin, T Shlomi Bioinformatics 26 (12), i255-i260, 2010 | 303 | 2010 |
Bringing metabolic networks to life: convenience rate law and thermodynamic constraints W Liebermeister, E Klipp Theoretical Biology and Medical Modelling 3, 41, 2006 | 299 | 2006 |
Global characterization of in vivo enzyme catalytic rates and their correspondence to in vitro kcat measurements D Davidi, E Noor, W Liebermeister, A Bar-Even, A Flamholz, K Tummler, ... Proceedings of the National Academy of Sciences 113 (12), 3401-3406, 2016 | 255 | 2016 |
Mathematical modeling of intracellular signaling pathways E Klipp, W Liebermeister BMC neuroscience 7, 1-16, 2006 | 222 | 2006 |
Spanning high-dimensional expression space using ribosome-binding site combinatorics L Zelcbuch, N Antonovsky, A Bar-Even, A Levin-Karp, U Barenholz, ... Nucleic acids research 41 (9), e98-e98, 2013 | 218 | 2013 |
SBML Level 3: an extensible format for the exchange and reuse of biological models SM Keating, D Waltemath, M König, F Zhang, A Dräger, C Chaouiya, ... Molecular systems biology 16 (8), e9110, 2020 | 211 | 2020 |
The protein cost of metabolic fluxes: prediction from enzymatic rate laws and cost minimization E Noor, A Flamholz, A Bar-Even, D Davidi, R Milo, W Liebermeister PLoS computational biology 12 (11), e1005167, 2016 | 185 | 2016 |
Modular rate laws for enzymatic reactions: thermodynamics, elasticities and implementation W Liebermeister, J Uhlendorf, E Klipp Bioinformatics 26 (12), 1528-1534, 2010 | 182 | 2010 |
Systematic construction of kinetic models from genome-scale metabolic networks NJ Stanford, T Lubitz, K Smallbone, E Klipp, P Mendes, W Liebermeister PloS one 8 (11), e79195, 2013 | 142 | 2013 |
A note on the kinetics of enzyme action: a decomposition that highlights thermodynamic effects E Noor, A Flamholz, W Liebermeister, A Bar-Even, R Milo FEBS letters 587 (17), 2772-2777, 2013 | 142 | 2013 |