Response to PD-1 blockade in microsatellite stable metastatic colorectal cancer harboring a POLE mutation J Gong, C Wang, PP Lee, P Chu, M Fakih Journal of the National Comprehensive Cancer Network 15 (2), 142-147, 2017 | 220 | 2017 |
Clinical response to immunotherapy targeting programmed cell death receptor 1/programmed cell death ligand 1 in patients with treatment-resistant microsatellite stable … C Wang, J Sandhu, C Ouyang, J Ye, PP Lee, M Fakih JAMA network Open 4 (8), e2118416-e2118416, 2021 | 82 | 2021 |
Regorafenib and nivolumab or pembrolizumab combination and circulating tumor DNA response assessment in refractory microsatellite stable colorectal cancer C Wang, D Chevalier, J Saluja, J Sandhu, C Lau, M Fakih The oncologist 25 (8), e1188-e1194, 2020 | 78 | 2020 |
Immune overdrive signature in colorectal tumor subset predicts poor clinical outcome M Fakih, C Ouyang, C Wang, TY Tu, MC Gozo, M Cho, M Sy, ... The Journal of clinical investigation 129 (10), 4464-4476, 2019 | 71 | 2019 |
Myeloid cell–targeted STAT3 inhibition sensitizes head and neck cancers to radiotherapy and T cell–mediated immunity D Moreira, S Sampath, H Won, SV White, YL Su, M Alcantara, C Wang, ... The Journal of clinical investigation 131 (2), 2021 | 57 | 2021 |
Immune profiling of microsatellite instability-high and polymerase ε (POLE)-mutated metastatic colorectal tumors identifies predictors of response to anti-PD-1 therapy W Chongkai, G Jun, YT Travis, LP Peter, F Marwan Journal of gastrointestinal oncology 9 (3), 404, 2018 | 57 | 2018 |
The non-muscle-myosin-II heavy chain Myh9 mediates colitis-induced epithelium injury by restricting Lgr5+ stem cells B Zhao, Z Qi, Y Li, C Wang, W Fu, YG Chen Nature communications 6 (1), 7166, 2015 | 55 | 2015 |
Oncogenic function of DACT1 in colon cancer through the regulation of β-catenin G Yuan, C Wang, C Ma, N Chen, Q Tian, T Zhang, W Fu PloS one 7 (3), e34004, 2012 | 50 | 2012 |
Targeting KRAS in colorectal cancer C Wang, M Fakih Current Oncology Reports 23, 1-10, 2021 | 37 | 2021 |
Phenotypic switching of naïve T cells to immune-suppressive Treg-like cells by mutant KRAS A Kalvala, P Wallet, L Yang, C Wang, H Li, A Nam, A Nathan, ... Journal of clinical medicine 8 (10), 1726, 2019 | 36 | 2019 |
Combined checkpoint inhibition and chemotherapy: new era of 1st-line treatment for non-small-cell lung cancer C Wang, P Kulkarni, R Salgia Molecular Therapy-Oncolytics 13, 1-6, 2019 | 35 | 2019 |
Regorafenib, ipilimumab, and nivolumab for patients with microsatellite stable colorectal cancer and disease progression with prior chemotherapy: a phase 1 nonrandomized … M Fakih, J Sandhu, D Lim, X Li, S Li, C Wang JAMA oncology 9 (5), 627-634, 2023 | 32 | 2023 |
A Pilot Feasibility Study of Yttrium‐90 Liver Radioembolization Followed by Durvalumab and Tremelimumab in Patients with Microsatellite Stable Colorectal Cancer Liver Metastases C Wang, J Park, C Ouyang, JA Longmate, M Tajon, J Chao, D Lim, ... The Oncologist 25 (5), 382-e776, 2020 | 31 | 2020 |
Evaluation of comparative surveillance strategies of circulating tumor DNA, imaging, and carcinoembryonic antigen levels in patients with resected colorectal cancer M Fakih, J Sandhu, C Wang, J Kim, YJ Chen, L Lai, K Melstrom, A Kaiser JAMA Network Open 5 (3), e221093-e221093, 2022 | 29 | 2022 |
IL-2 and IL-6 cooperate to enhance the generation of influenza-specific CD8 T cells responding to live influenza virus in aged mice and humans X Zhou, JW Hopkins, C Wang, V Brahmakshatriya, SL Swain, GA Kuchel, ... Oncotarget 7 (26), 39171, 2016 | 29 | 2016 |
Wild‐type APC Is Associated with Poor Survival in Metastatic Microsatellite Stable Colorectal Cancer C Wang, C Ouyang, M Cho, J Ji, J Sandhu, A Goel, M Kahn, M Fakih The oncologist 26 (3), 208-214, 2021 | 26 | 2021 |
Targeting KRASG12C-Mutated Advanced Colorectal Cancer: Research and Clinical Developments J Ji, C Wang, M Fakih OncoTargets and therapy, 747-756, 2022 | 22 | 2022 |
Targeting MSS colorectal cancer with immunotherapy: are we turning the corner? C Wang, M Fakih Expert Opinion on Biological Therapy 21 (10), 1347-1357, 2021 | 21 | 2021 |
MAP2K1 mutations in advanced colorectal cancer predict poor response to anti-EGFR therapy and to vertical targeting of MAPK pathway J Chuang, C Wang, Y Guo, V Valenzuela, J Wu, M Fakih Clinical Colorectal Cancer 20 (1), 72-78, 2021 | 15 | 2021 |
320MO A phase I clinical trial of regorafenib, ipilimumab, and nivolumab (RIN) in chemotherapy resistant MSS metastatic colorectal cancer (mCRC) MG Fakih, J Sandhu, D Lim, SM Li, C Wang Annals of Oncology 33, S684, 2022 | 11 | 2022 |