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Randall J Roper
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Understanding the basis for Down syndrome phenotypes
RJ Roper, RH Reeves
PLoS genetics 2 (3), e50, 2006
2942006
Defective cerebellar response to mitogenic Hedgehog signaling in Down's syndrome mice
RJ Roper, LL Baxter, NG Saran, DK Klinedinst, PA Beachy, RH Reeves
Proceedings of the National Academy of Sciences 103 (5), 1452-1456, 2006
2532006
Trisomy for the Down syndrome ‘critical region’is necessary but not sufficient for brain phenotypes of trisomic mice
LE Olson, RJ Roper, CL Sengstaken, EA Peterson, V Aquino, Z Galdzicki, ...
Human molecular genetics 16 (7), 774-782, 2007
2362007
Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes
LE Olson, RJ Roper, LL Baxter, EJ Carlson, CJ Epstein, RH Reeves
Developmental dynamics: an official publication of the American Association …, 2004
2132004
Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn
LG Reinholdt, Y Ding, GT Gilbert, A Czechanski, JP Solzak, RJ Roper, ...
Mammalian genome 22, 685-691, 2011
2052011
Ultrasonic enhancement of antibiotic action on gram-negative bacteria
WG Pitt, MO McBride, JK Lunceford, RJ Roper, RD Sagers
Antimicrobial agents and chemotherapy 38 (11), 2577-2582, 1994
1901994
New genetic loci that control susceptibility and symptoms of experimental allergic encephalomyelitis in inbred mice
RJ Butterfield, JD Sudweeks, EP Blankenhorn, R Korngold, JC Marini, ...
The Journal of Immunology 161 (4), 1860-1867, 1998
1851998
Identification of quantitative trait loci governing arthritis severity and humoral responses in the murine model of Lyme disease
JJ Weis, BA McCracken, Y Ma, D Fairbairn, RJ Roper, TB Morrison, ...
The Journal of Immunology 162 (2), 948-956, 1999
1421999
Genetic analysis of disease subtypes and sexual dimorphisms in mouse experimental allergic encephalomyelitis (EAE): relapsing/remitting and monophasic remitting/nonrelapsing …
RJ Butterfield, EP Blankenhorn, RJ Roper, JF Zachary, RW Doerge, ...
The Journal of Immunology 162 (5), 3096-3102, 1999
1261999
Identification of genetic loci controlling the characteristics and severity of brain and spinal cord lesions in experimental allergic encephalomyelitis
RJ Butterfield, EP Blankenhorn, RJ Roper, JF Zachary, RW Doerge, ...
The American journal of pathology 157 (2), 637-645, 2000
1192000
Perinatal loss of Ts65Dn Down syndrome mice
RJ Roper, HK St. John, J Philip, A Lawler, RH Reeves
Genetics 172 (1), 437-443, 2006
952006
A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog
RJ Roper, JF VanHorn, CC Cain, RH Reeves
Mechanisms of Development 126 (3-4), 212-219, 2009
852009
Obstructive sleep apnea in young infants with Down syndrome evaluated in a Down syndrome specialty clinic
A Goffinski, MA Stanley, N Shepherd, N Duvall, SB Jenkinson, C Davis, ...
American journal of medical genetics Part A 167 (2), 324-330, 2015
832015
Genetic control of susceptibility to experimental Lyme arthritis is polygenic and exhibits consistent linkage to multiple loci on chromosome 5 in four independent mouse crosses
RJ Roper, JJ Weis, BA McCracken, CB Green, Y Ma, KS Weber, ...
Genes & Immunity 2 (7), 388-397, 2001
812001
Cutting edge: Autoimmune disease in day 3 thymectomized mice is actively controlled by endogenous disease-specific regulatory T cells
ET Samy, KM Wheeler, RJ Roper, C Teuscher, KSK Tung
The Journal of Immunology 180 (7), 4366-4370, 2008
762008
Interacting quantitative trait loci control phenotypic variation in murine estradiol-regulated responses
RJ Roper, JS Griffith, CR Lyttle, RW Doerge, AW McNabb, RE Broadbent, ...
Endocrinology 140 (2), 556-561, 1999
681999
Clinical identification of feeding and swallowing disorders in 0–6 month old infants with Down syndrome
MA Stanley, N Shepherd, N Duvall, SB Jenkinson, HE Jalou, DC Givan, ...
American Journal of Medical Genetics Part A 179 (2), 177-182, 2019
672019
The power of comparative and developmental studies for mouse models of Down syndrome
CS Moore, RJ Roper
Mammalian genome 18 (6), 431-443, 2007
662007
Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice
JD Blazek, A Gaddy, R Meyer, RJ Roper, J Li
Bone 48 (2), 275-280, 2011
582011
Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a
JD Blazek, I Abeysekera, J Li, RJ Roper
Human molecular genetics 24 (20), 5687-5696, 2015
552015
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