Understanding the basis for Down syndrome phenotypes RJ Roper, RH Reeves PLoS genetics 2 (3), e50, 2006 | 294 | 2006 |
Defective cerebellar response to mitogenic Hedgehog signaling in Down's syndrome mice RJ Roper, LL Baxter, NG Saran, DK Klinedinst, PA Beachy, RH Reeves Proceedings of the National Academy of Sciences 103 (5), 1452-1456, 2006 | 253 | 2006 |
Trisomy for the Down syndrome ‘critical region’is necessary but not sufficient for brain phenotypes of trisomic mice LE Olson, RJ Roper, CL Sengstaken, EA Peterson, V Aquino, Z Galdzicki, ... Human molecular genetics 16 (7), 774-782, 2007 | 236 | 2007 |
Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes LE Olson, RJ Roper, LL Baxter, EJ Carlson, CJ Epstein, RH Reeves Developmental dynamics: an official publication of the American Association …, 2004 | 213 | 2004 |
Molecular characterization of the translocation breakpoints in the Down syndrome mouse model Ts65Dn LG Reinholdt, Y Ding, GT Gilbert, A Czechanski, JP Solzak, RJ Roper, ... Mammalian genome 22, 685-691, 2011 | 205 | 2011 |
Ultrasonic enhancement of antibiotic action on gram-negative bacteria WG Pitt, MO McBride, JK Lunceford, RJ Roper, RD Sagers Antimicrobial agents and chemotherapy 38 (11), 2577-2582, 1994 | 190 | 1994 |
New genetic loci that control susceptibility and symptoms of experimental allergic encephalomyelitis in inbred mice RJ Butterfield, JD Sudweeks, EP Blankenhorn, R Korngold, JC Marini, ... The Journal of Immunology 161 (4), 1860-1867, 1998 | 185 | 1998 |
Identification of quantitative trait loci governing arthritis severity and humoral responses in the murine model of Lyme disease JJ Weis, BA McCracken, Y Ma, D Fairbairn, RJ Roper, TB Morrison, ... The Journal of Immunology 162 (2), 948-956, 1999 | 142 | 1999 |
Genetic analysis of disease subtypes and sexual dimorphisms in mouse experimental allergic encephalomyelitis (EAE): relapsing/remitting and monophasic remitting/nonrelapsing … RJ Butterfield, EP Blankenhorn, RJ Roper, JF Zachary, RW Doerge, ... The Journal of Immunology 162 (5), 3096-3102, 1999 | 126 | 1999 |
Identification of genetic loci controlling the characteristics and severity of brain and spinal cord lesions in experimental allergic encephalomyelitis RJ Butterfield, EP Blankenhorn, RJ Roper, JF Zachary, RW Doerge, ... The American journal of pathology 157 (2), 637-645, 2000 | 119 | 2000 |
Perinatal loss of Ts65Dn Down syndrome mice RJ Roper, HK St. John, J Philip, A Lawler, RH Reeves Genetics 172 (1), 437-443, 2006 | 95 | 2006 |
A neural crest deficit in Down syndrome mice is associated with deficient mitotic response to Sonic hedgehog RJ Roper, JF VanHorn, CC Cain, RH Reeves Mechanisms of Development 126 (3-4), 212-219, 2009 | 85 | 2009 |
Obstructive sleep apnea in young infants with Down syndrome evaluated in a Down syndrome specialty clinic A Goffinski, MA Stanley, N Shepherd, N Duvall, SB Jenkinson, C Davis, ... American journal of medical genetics Part A 167 (2), 324-330, 2015 | 83 | 2015 |
Genetic control of susceptibility to experimental Lyme arthritis is polygenic and exhibits consistent linkage to multiple loci on chromosome 5 in four independent mouse crosses RJ Roper, JJ Weis, BA McCracken, CB Green, Y Ma, KS Weber, ... Genes & Immunity 2 (7), 388-397, 2001 | 81 | 2001 |
Cutting edge: Autoimmune disease in day 3 thymectomized mice is actively controlled by endogenous disease-specific regulatory T cells ET Samy, KM Wheeler, RJ Roper, C Teuscher, KSK Tung The Journal of Immunology 180 (7), 4366-4370, 2008 | 76 | 2008 |
Interacting quantitative trait loci control phenotypic variation in murine estradiol-regulated responses RJ Roper, JS Griffith, CR Lyttle, RW Doerge, AW McNabb, RE Broadbent, ... Endocrinology 140 (2), 556-561, 1999 | 68 | 1999 |
Clinical identification of feeding and swallowing disorders in 0–6 month old infants with Down syndrome MA Stanley, N Shepherd, N Duvall, SB Jenkinson, HE Jalou, DC Givan, ... American Journal of Medical Genetics Part A 179 (2), 177-182, 2019 | 67 | 2019 |
The power of comparative and developmental studies for mouse models of Down syndrome CS Moore, RJ Roper Mammalian genome 18 (6), 431-443, 2007 | 66 | 2007 |
Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice JD Blazek, A Gaddy, R Meyer, RJ Roper, J Li Bone 48 (2), 275-280, 2011 | 58 | 2011 |
Rescue of the abnormal skeletal phenotype in Ts65Dn Down syndrome mice using genetic and therapeutic modulation of trisomic Dyrk1a JD Blazek, I Abeysekera, J Li, RJ Roper Human molecular genetics 24 (20), 5687-5696, 2015 | 55 | 2015 |