Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists A Gillis, AB Gondin, A Kliewer, J Sanchez, HD Lim, C Alamein, ... Science signaling 13 (625), eaaz3140, 2020 | 281 | 2020 |
Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization E Miess, AB Gondin, A Yousuf, R Steinborn, N Mösslein, Y Yang, ... Science signaling 11 (539), eaas9609, 2018 | 122 | 2018 |
Plasma membrane localization of the μ-opioid receptor controls spatiotemporal signaling ML Halls, HR Yeatman, CJ Nowell, GL Thompson, AB Gondin, ... Science signaling 9 (414), ra16-ra16, 2016 | 80 | 2016 |
Selective G protein signaling driven by substance P–neurokinin receptor dynamics JA Harris, B Faust, AB Gondin, MA Dämgen, CM Suomivuori, NA Veldhuis, ... Nature chemical biology 18 (1), 109-115, 2022 | 59 | 2022 |
Fluorescently labeled morphine derivatives for bioimaging studies R Lam, AB Gondin, M Canals, B Kellam, SJ Briddon, B Graham, ... Journal of Medicinal Chemistry 61 (3), 1316-1329, 2018 | 26 | 2018 |
Ligand-dependent spatiotemporal signaling profiles of the μ-opioid receptor are controlled by distinct protein-interaction networks S Civciristov, C Huang, B Liu, EA Marquez, AB Gondin, RB Schittenhelm, ... Journal of Biological Chemistry 294 (44), 16198-16213, 2019 | 23 | 2019 |
GRK mediates μ-opioid receptor plasma membrane reorganization AB Gondin, ML Halls, M Canals, SJ Briddon Frontiers in Molecular Neuroscience 12, 104, 2019 | 23 | 2019 |
Opioid pharmacology under the microscope D Jullié, AB Gondin, M Von Zastrow, M Canals Molecular Pharmacology 98 (4), 425-432, 2020 | 21 | 2020 |
A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes QN Mai, P Shenoy, T Quach, JS Retamal, AB Gondin, HR Yeatman, ... Journal of Biological Chemistry 296, 2021 | 19 | 2021 |
The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability S Peng, MS Grace, AB Gondin, JS Retamal, L Dill, W Darby, NW Bunnett, ... Laboratory Investigation 100 (8), 1057-1067, 2020 | 18 | 2020 |
Serotonin-induced vascular permeability is mediated by transient receptor potential vanilloid 4 in the airways and upper gastrointestinal tract of mice JS Retamal, MS Grace, LK Dill, P Ramirez-Garcia, S Peng, AB Gondin, ... Laboratory Investigation 101 (7), 851-864, 2021 | 16 | 2021 |
Clathrin and GRK2/3 inhibitors block δ-opioid receptor internalization in myenteric neurons and inhibit neuromuscular transmission in the mouse colon JJ DiCello, P Rajasekhar, EM Eriksson, A Saito, AB Gondin, NA Veldhuis, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 317 (2 …, 2019 | 11 | 2019 |
Importance of receptor expression in the classification of novel ligands at the M2 muscarinic acetylcholine receptor Y Jiang, M Yeasmin, AB Gondin, A Christopoulos, C Valant, WAC Burger, ... British Journal of Pharmacology 181 (14), 2338-2350, 2024 | 10 | 2024 |
Positive allosteric modulation of endogenous delta opioid receptor signaling in the enteric nervous system is a potential treatment for gastrointestinal motility disorders JJ DiCello, SE Carbone, A Saito, V Pham, A Szymaszkiewicz, AB Gondin, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 322 (1 …, 2022 | 9 | 2022 |
Agonist-dependent development of delta opioid receptor tolerance in the colon JJ DiCello, A Saito, P Rajasekhar, BW Sebastian, RM McQuade, ... Cellular and Molecular Life Sciences 76, 3033-3050, 2019 | 8 | 2019 |
G protein-coupled receptor trafficking and signaling: new insights into the enteric nervous system SE Carbone, NA Veldhuis, AB Gondin, DP Poole American Journal of Physiology-Gastrointestinal and Liver Physiology, 2019 | 8 | 2019 |
Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists (vol 13, eaaz3140, 2020) A Gillis, AB Gondin, A Kliewer, J Sanchez, HD Lim, C Alamein, ... SCIENCE SIGNALING 14 (670), 2021 | 1 | 2021 |
Key phosphorylation sites for robust β-arrestin2 binding at the MOR revisited O Underwood, S Fritzwanker, J Glenn, NK Blum, A Batista-Gondin, ... Communications Biology 7 (1), 933, 2024 | | 2024 |
Mechanistic overview of how opioid analgesics promote constipation JJ Di Cello, AB Gondin, SE Carbone, DP Poole Treatments, Mechanisms, and Adverse Reactions of Anesthetics and Analgesics …, 2022 | | 2022 |
Ferkinase Signals JS Retamal, MS Grace, LK Dill, P Ramirez-Garcia, S Peng, AB Gondin, ... | | |