Modulating the masters: chemical tools to dissect CBP and p300 function ME Breen, AK Mapp Current opinion in chemical biology 45, 195-203, 2018 | 66 | 2018 |
Small molecule substrate phosphorylation site inhibitors of protein kinases: Approaches and challenges ME Breen, MB Soellner ACS chemical biology 10 (1), 175-189, 2015 | 66 | 2015 |
A photoreactive crystalline quasiracemate RC Grove, SH Malehorn, ME Breen, KA Wheeler Chemical communications 46 (39), 7322-7324, 2010 | 52 | 2010 |
A bifunctional amino acid enables both covalent chemical capture and isolation of in vivo protein–protein interactions CM Joiner, ME Breen, J Clayton, AK Mapp ChemBioChem 18 (2), 181-184, 2017 | 32 | 2017 |
Discovery and development of a small molecule library with lumazine synthase inhibitory activity A Talukdar, M Breen, A Bacher, B Illarionov, M Fischer, G Georg, QZ Ye, ... The Journal of organic chemistry 74 (15), 5123-5134, 2009 | 31 | 2009 |
Exquisitely specific bisubstrate inhibitors of c-Src kinase KR Brandvold, SM Santos, ME Breen, EJ Lachacz, ME Steffey, ... ACS chemical biology 10 (6), 1387-1391, 2015 | 30 | 2015 |
Pharmaceutical solvate formation for the incorporation of the antimicrobial agent hydrogen peroxide KM Kersten, ME Breen, AK Mapp, AJ Matzger Chemical Communications 54 (67), 9286-9289, 2018 | 25 | 2018 |
Substrate Activity Screening with Kinases: Discovery of Small‐Molecule Substrate‐Competitive c‐Src Inhibitors ME Breen, ME Steffey, EJ Lachacz, FE Kwarcinski, CC Fox, MB Soellner Angewandte Chemie International Edition 53 (27), 7010-7013, 2014 | 22 | 2014 |
Novel inhibitors of bacterial virulence: development of 5, 6-dihydrobenzo [h] quinazolin-4 (3H)-ones for the inhibition of group A streptococcal streptokinase expression BD Yestrepsky, Y Xu, ME Breen, X Li, WG Rajeswaran, JG Ryu, ... Bioorganic & medicinal chemistry 21 (7), 1880-1897, 2013 | 17 | 2013 |
Structural studies of enantiomers, racemates, and quasiracemates. 2-(3-bromophenoxy) propionic acid and 2-(3-methoxyphenoxy) propionic acid ME Breen, SL Tameze, WG Dougherty, WS Kassel, KA Wheeler Crystal Growth and Design 8 (10), 3863-3870, 2008 | 16 | 2008 |
Electron‐deficient p‐benzoyl‐l‐phenylalanine derivatives increase covalent chemical capture yields for protein–protein interactions CM Joiner, ME Breen, AK Mapp Protein Science 28 (6), 1163-1170, 2019 | 9 | 2019 |
Garcinolic acid distinguishes between GACKIX domains and modulates interaction networks ME Breen, ST Joy, OJ Baruti, MS Beyersdorf, MJ Henley, SN De Salle, ... ChemBioChem, e202300439, 2023 | 2 | 2023 |
Investigation of the phosphorylation status of the Candida glabrata Pdr1 transcription factor J McCallum, S Stapleton, E Chandler, M Breen PROTEIN SCIENCE 32, 2023 | | 2023 |
Track: Synthetic Biology & Biosensing: Engineering Protein Components Development of a Genetic Code Expansion System in Candida glabrata M Breen, R Singer PROTEIN SCIENCE 32, 2023 | | 2023 |
INHIBITION OF TRANSCRIPTIONAL ACTIVATOR-COACTIVATOR PROTEIN-PROTEIN INTERACTIONS WITH NATURAL PRODUCTS M Breen, S Joy, M Beyersdorf, M Henley, S De Salle, A Mapp PROTEIN SCIENCE 28, 42-43, 2019 | | 2019 |
Garcinolic Acid Inhibits Transcriptional Activator Interactions with the Creb Binding Protein Kix Domain M Breen, O Baruti, M Beyersdorf, S Joy, S DeSalle, A Mapp PROTEIN SCIENCE 27, 231-231, 2018 | | 2018 |
Development of a Chemical Toolbox for Dissecting Activator-Coactivator Interactions In Vivo M Breen, A Mapp PROTEIN SCIENCE 26, 37-37, 2017 | | 2017 |
Unnatural amino acids with enhanced reactivity for in vivo covalent chemical capture C Joiner, M Breen, A Mapp ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |
Substrate-Competitive Inhibitors of c-Src Kinase. ME Breen | | 2014 |
Substrate activity screening methodology for protein tyrosine kinases ME Breen, ME Steffey, MB Soellner ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013 | | 2013 |