Intratumor heterogeneity and branched evolution revealed by multiregion sequencing M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ... New England journal of medicine 366 (10), 883-892, 2012 | 8610 | 2012 |
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing M Gerlinger, S Horswell, J Larkin, AJ Rowan, MP Salm, I Varela, R Fisher, ... Nature genetics 46 (3), 225-233, 2014 | 1371 | 2014 |
SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair N Kanu, E Grönroos, P Martinez, RA Burrell, XY Goh, J Bartkova, ... Oncogene 34 (46), 5699-5708, 2015 | 187 | 2015 |
Systematic Evaluation of the Prognostic Impact and Intratumour Heterogeneity of Clear Cell Renal Cell Carcinoma Biomarkers S Gulati, P Martinez, T Joshi, NJ Birkbak, CR Santos, AJ Rowan, ... European urology 66 (5), 936-948, 2014 | 173 | 2014 |
Evolutionary history of human colitis-associated colorectal cancer AM Baker, W Cross, K Curtius, I Al Bakir, CHR Choi, HL Davis, D Temko, ... Gut 68 (6), 985-995, 2019 | 143 | 2019 |
Genome‐wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target M Gerlinger, CR Santos, B Spencer‐Dene, P Martinez, D Endesfelder, ... The Journal of pathology 227 (2), 146-156, 2012 | 136 | 2012 |
The evolutionary landscape of colorectal tumorigenesis W Cross, M Kovac, V Mustonen, D Temko, H Davis, AM Baker, S Biswas, ... Nature ecology & evolution 2 (10), 1661-1672, 2018 | 116 | 2018 |
Parallel evolution of tumour subclones mimics diversity between tumours P Martinez, NJ Birkbak, M Gerlinger, N McGranahan, RA Burrell, ... The Journal of pathology 230 (4), 356-364, 2013 | 102 | 2013 |
Dynamic clonal equilibrium and predetermined cancer risk in Barrett’s oesophagus P Martinez, MR Timmer, CT Lau, S Calpe, MC Sancho-Serra, D Straub, ... Nature communications 7 (1), 12158, 2016 | 91 | 2016 |
Comprehensive characterization of claudin-low breast tumors reflects the impact of the cell-of-origin on cancer evolution RM Pommier, A Sanlaville, L Tonon, J Kielbassa, E Thomas, A Ferrari, ... Nature communications 11 (1), 3431, 2020 | 88 | 2020 |
Derivation of genetic biomarkers for cancer risk stratification in Barrett’s oesophagus: a prospective cohort study MR Timmer, P Martinez, CT Lau, WM Westra, S Calpe, AM Rygiel, ... Gut 65 (10), 1602-1610, 2016 | 55 | 2016 |
Evolution of Barrett’s esophagus through space and time at single-crypt and whole-biopsy levels P Martinez, D Mallo, TG Paulson, X Li, CA Sanchez, BJ Reid, TA Graham, ... Nature communications 9 (1), 794, 2018 | 54 | 2018 |
Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus DL Lavery, P Martinez, LJ Gay, B Cereser, MR Novelli, M Rodriguez-Justo, ... Gut 65 (6), 907-913, 2016 | 51 | 2016 |
Immunosuppressive niche engineering at the onset of human colorectal cancer CD Gatenbee, AM Baker, RO Schenck, M Strobl, J West, MP Neves, ... Nature Communications 13 (1), 1798, 2022 | 27 | 2022 |
Computational optimisation of targeted DNA sequencing for cancer detection P Martinez, N McGranahan, NJ Birkbak, M Gerlinger, C Swanton Scientific Reports 3 (1), 3309, 2013 | 27 | 2013 |
Structure and stability insights into tumour suppressor p53 evolutionary related proteins B Pagano, A Jama, P Martinez, E Akanho, TTT Bui, AF Drake, F Fraternali, ... PLoS One 8 (10), e76014, 2013 | 25 | 2013 |
Unmet Needs and Perspectives in Oral Cancer Prevention J Bouaoud, P Bossi, M Elkabets, S Schmitz, LC van Kempen, P Martinez, ... Cancers 14 (7), 1815, 2022 | 23 | 2022 |
Protein–Water Interactions in MD Simulations: POPS/POPSCOMP Solvent Accessibility Analysis, Solvation Forces and Hydration Sites A Fornili, F Autore, N Chakroun, P Martinez, F Fraternali Computational Drug Discovery and Design, 375-392, 2012 | 22 | 2012 |
Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity J Uchuya-Castillo, N Aznar, C Frau, P Martinez, C Le Nevé, L Marisa, ... Oncotarget 9 (57), 30979, 2018 | 17 | 2018 |
Stabilising selection causes grossly altered but stable karyotypes in metastatic colorectal cancer W Cross, M Mossner, S Nowinski, G Cresswell, A Banerjee, M Williams, ... Biorxiv, 2020.03. 26.007138, 2020 | 15 | 2020 |