| Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction T Minamino, H Miyauchi, T Yoshida, Y Ishida, H Yoshida, I Komuro Circulation 105 (13), 1541-1544, 2002 | 1268 | 2002 |
| Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure T Oka, S Hikoso, O Yamaguchi, M Taneike, T Takeda, T Tamai, J Oyabu, ... Nature 485 (7397), 251-255, 2012 | 1179 | 2012 |
| The Japanese Society of Hypertension guidelines for the management of hypertension (JSH 2014) K Shimamoto, K Ando, T Fujita, N Hasebe, J Higaki, M Horiuchi, Y Imai, ... Hypertension Research 37 (4), 253-390, 2014 | 1146 | 2014 |
| p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload M Sano, T Minamino, H Toko, H Miyauchi, M Orimo, Y Qin, H Akazawa, ... Nature 446 (7134), 444-448, 2007 | 1023 | 2007 |
| A crucial role for adipose tissue p53 in the regulation of insulin resistance T Minamino, M Orimo, I Shimizu, T Kunieda, M Yokoyama, T Ito, A Nojima, ... Nature medicine 15 (9), 1082-1087, 2009 | 951 | 2009 |
| Endothelin stimulates c‐fos and c‐myc expression and proliferation of vascular smooth muscle cells I Komuro, H Kurihara, T Sugiyama, F Takaku, Y Yazaki FEBS letters 238 (2), 249-252, 1988 | 922 | 1988 |
| Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes K Matsuura, T Nagai, N Nishigaki, T Oyama, J Nishi, H Wada, M Sano, ... Journal of Biological Chemistry 279 (12), 11384-11391, 2004 | 859 | 2004 |
| A cross-population atlas of genetic associations for 220 human phenotypes S Sakaue, M Kanai, Y Tanigawa, J Karjalainen, M Kurki, S Koshiba, ... Nature genetics 53 (10), 1415-1424, 2021 | 847 | 2021 |
| Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. R Aikawa, I Komuro, T Yamazaki, Y Zou, S Kudoh, M Tanaka, I Shiojima, ... The Journal of clinical investigation 100 (7), 1813-1821, 1997 | 845 | 1997 |
| Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II Y Zou, H Akazawa, Y Qin, M Sano, H Takano, T Minamino, N Makita, ... Nature cell biology 6 (6), 499-506, 2004 | 776 | 2004 |
| G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes M Harada, Y Qin, H Takano, T Minamino, Y Zou, H Toko, M Ohtsuka, ... Nature medicine 11 (3), 305-311, 2005 | 747 | 2005 |
| Vascular cell senescence: contribution to atherosclerosis T Minamino, I Komuro Circulation research 100 (1), 15-26, 2007 | 717 | 2007 |
| Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation Y Hiroi, S Kudoh, K Monzen, Y Ikeda, Y Yazaki, R Nagai, I Komuro Nature genetics 28 (3), 276-280, 2001 | 692 | 2001 |
| Csx: a murine homeobox-containing gene specifically expressed in the developing heart. I Komuro, S Izumo Proceedings of the National Academy of Sciences 90 (17), 8145-8149, 1993 | 683 | 1993 |
| Developmental stage-specific biphasic roles of Wnt/β-catenin signaling in cardiomyogenesis and hematopoiesis AT Naito, I Shiojima, H Akazawa, K Hidaka, T Morisaki, A Kikuchi, ... Proceedings of the National Academy of Sciences 103 (52), 19812-19817, 2006 | 630 | 2006 |
| Stretching cardiac myocytes stimulates protooncogene expression. I Komuro, T Kaida, Y Shibazaki, M Kurabayashi, Y Katoh, E Hoh, ... Journal of Biological Chemistry 265 (7), 3595-3598, 1990 | 590 | 1990 |
| Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease T Minamino, I Komuro, M Kitakaze Circulation research 107 (9), 1071-1082, 2010 | 566 | 2010 |
| Pathophysiology of myocardial reperfusion injury: preconditioning, postconditioning, and translational aspects of protective measures S Sanada, I Komuro, M Kitakaze American Journal of Physiology-Heart and Circulatory Physiology 301 (5 …, 2011 | 553 | 2011 |
| Endothelin-1 Is Involved in Mechanical Stress-induced Cardiomyocyte Hypertrophy (∗) T Yamazaki, I Komuro, S Kudoh, Y Zou, I Shiojima, Y Hiroi, T Mizuno, ... Journal of Biological Chemistry 271 (6), 3221-3228, 1996 | 549 | 1996 |
| Increased insulin sensitivity and hypoglycaemia in mice lacking the p85α subunit of phosphoinositide 3–kinase Y Terauchi, Y Tsuji, S Satoh, H Minoura, K Murakami, A Okuno, K Inukai, ... Nature genetics 21 (2), 230-235, 1999 | 535 | 1999 |
