Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic SW Way, JR Podojil, BL Clayton, A Zaremba, TL Collins, RB Kunjamma, ... Nature communications 6 (1), 6532, 2015 | 115 | 2015 |
The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis P Brugarolas, F Movahedzadeh, Y Wang, N Zhang, IL Bartek, YN Gao, ... Journal of biological chemistry 287 (45), 37703-37712, 2012 | 69 | 2012 |
Redox signaling in human pathogens PR Chen, P Brugarolas, C He Antioxidants & redox signaling 14 (6), 1107-1118, 2011 | 69 | 2011 |
Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR Q Ji, L Zhang, MB Jones, F Sun, X Deng, H Liang, H Cho, P Brugarolas, ... Proceedings of the National Academy of Sciences 110 (13), 5010-5015, 2013 | 43 | 2013 |
Phosphorylation state of ZFP24 controls oligodendrocyte differentiation B Elbaz, JD Aaker, S Isaac, A Kolarzyk, P Brugarolas, A Eden, B Popko Cell reports 23 (8), 2254-2263, 2018 | 34 | 2018 |
Development of a PET radioligand for potassium channels to image CNS demyelination P Brugarolas, JE Sánchez-Rodríguez, HM Tsai, F Basuli, SH Cheng, ... Scientific reports 8 (1), 607, 2018 | 34 | 2018 |
Structure-activity relationship studies of four novel 4-aminopyridine K+ channel blockers S Rodríguez-Rangel, AD Bravin, KM Ramos-Torres, P Brugarolas, ... Scientific reports 10 (1), 52, 2020 | 31 | 2020 |
Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques NJ Guehl, KM Ramos-Torres, C Linnman, SH Moon, M Dhaynaut, ... Journal of Cerebral Blood Flow & Metabolism 41 (7), 1721-1733, 2021 | 21 | 2021 |
Ordered circular mesoporosity induced by phospholipids J García-Martínez, P Brugarolas, S Domínguez-Domínguez Microporous and mesoporous materials 100 (1-3), 63-69, 2007 | 20 | 2007 |
Fifty years of radiopharmaceuticals P Brugarolas, J Comstock, DW Dick, T Ellmer, JW Engle, SE Lapi, ... Journal of nuclear medicine technology 48 (Supplement 1), 34S-39S, 2020 | 18 | 2020 |
Binding of ReO4 − with an engineered MoO4 2−-binding protein: towards a new approach in radiopharmaceutical applications BP Aryal, P Brugarolas, C He JBIC Journal of Biological Inorganic Chemistry 17, 97-106, 2012 | 18 | 2012 |
Synthesis of meta-substituted [18 F] 3-fluoro-4-aminopyridine via direct radiofluorination of pyridine N-oxides P Brugarolas, R Freifelder, SH Cheng, O DeJesus Chemical communications 52 (44), 7150-7152, 2016 | 17 | 2016 |
Remyelination therapy goes to trial for multiple sclerosis P Brugarolas, B Popko Neuroimmunology & Neuroinflammation 1 (2), e26, 2014 | 17 | 2014 |
Detecting demyelination by PET: the lesion as imaging target P Brugarolas, DS Reich, B Popko Molecular imaging 17, 1536012118785471, 2018 | 16 | 2018 |
Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus P Brugarolas, EM Duguid, W Zhang, CB Poor, C He Acta Crystallographica Section D: Biological Crystallography 67 (8), 707-715, 2011 | 15 | 2011 |
An efficient new method for the synthesis of 3‐[18F]fluoro‐4‐aminopyridine via Yamada‐Curtius rearrangement F Basuli, X Zhang, P Brugarolas, DS Reich, RE Swenson Journal of Labelled Compounds and Radiopharmaceuticals 61 (2), 112-117, 2018 | 13 | 2018 |
Radiolabeling with [11C] HCN for positron emission tomography YP Zhou, KJ Makaravage, P Brugarolas Nuclear medicine and biology 102, 56-86, 2021 | 12 | 2021 |
Evaluation of fluorinated cromolyn derivatives as potential therapeutics for Alzheimer’s disease TM Shoup, A Griciuc, MD Normandin, L Quinti, LV Walsh, M Dhaynaut, ... Journal of Alzheimer's Disease 80 (2), 775-786, 2021 | 8 | 2021 |
Heterologous saRNA prime, DNA dual-antigen boost SARS-CoV-2 vaccination elicits robust cellular immunogenicity and cross-variant neutralizing antibodies A Rice, M Verma, E Voigt, P Battisti, S Beaver, S Reed, K Dinkins, S Mody, ... Frontiers in Immunology 13, 910136, 2022 | 7 | 2022 |
PET imaging of mitochondrial function in acute doxorubicin-induced cardiotoxicity: a proof-of-principle study FJ Detmer, NM Alpert, SH Moon, M Dhaynaut, JL Guerrero, NJ Guehl, ... Scientific Reports 12 (1), 6122, 2022 | 7 | 2022 |