Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin F Schütt, S Davies, J Kopitz, FG Holz, ME Boulton Investigative ophthalmology & visual science 41 (8), 2303-2308, 2000 | 403 | 2000 |
Inhibition of lysosomal degradative functions in RPE cells by a retinoid component of lipofuscin. FG Holz, F Schütt, J Kopitz, GE Eldred, FE Kruse, HE Völcker, M Cantz Investigative ophthalmology & visual science 40 (3), 737-743, 1999 | 395 | 1999 |
Galectin-1 is a major receptor for ganglioside GM1, a product of the growth-controlling activity of a cell surface ganglioside sialidase, on human neuroblastoma cells in culture J Kopitz, C von Reitzenstein, M Burchert, M Cantz, HJ Gabius Journal of Biological Chemistry 273 (18), 11205-11211, 1998 | 332 | 1998 |
Negative regulation of neuroblastoma cell growth by carbohydrate-dependent surface binding of galectin-1 and functional divergence from galectin-3 J Kopitz, C von Reitzenstein, S André, H Kaltner, J Uhl, V Ehemann, ... Journal of Biological Chemistry 276 (38), 35917-35923, 2001 | 325 | 2001 |
Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium F Schutt, M Bergmann, FG Holz, J Kopitz Investigative ophthalmology & visual science 44 (8), 3663-3668, 2003 | 302 | 2003 |
Inhibition of the ATP‐driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2‐E may contribute to the pathogenesis of age‐related macular degeneration M Bergmann, F Schütt, FG Holz, J Kopitz The FASEB journal 18 (3), 562-564, 2004 | 282 | 2004 |
Nonselective autophagy of cytosolic enzymes by isolated rat hepatocytes. J Kopitz, GO Kisen, PB Gordon, P Bohley, PO Seglen The Journal of cell biology 111 (3), 941-953, 1990 | 275 | 1990 |
Early postoperative delirium after open-heart cardiac surgery is associated with decreased bispectral EEG and increased cortisol and interleukin-6 K Plaschke, P Fichtenkamm, C Schramm, S Hauth, E Martin, M Verch, ... Intensive care medicine 36, 2081-2089, 2010 | 218 | 2010 |
Lipids and lipid peroxidation products in the pathogenesis of age-related macular degeneration J Kopitz, FG Holz, E Kaemmerer, F Schutt Biochimie 86 (11), 825-831, 2004 | 196 | 2004 |
Tumor suppressor p16INK4a − modulator of glycomic profile and galectin‐1 expression to increase susceptibility to carbohydrate‐dependent induction of anoikis … S André, H Sanchez‐Ruderisch, H Nakagawa, M Buchholz, J Kopitz, ... The FEBS journal 274 (13), 3233-3256, 2007 | 194 | 2007 |
Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells J Kopitz, S Andre, C Von Reitzenstein, K Versluis, H Kaltner, RJ Pieters, ... Oncogene 22 (40), 6277-6288, 2003 | 180 | 2003 |
Effects of lipid peroxidation products on lipofuscinogenesis and autophagy in human retinal pigment epithelial cells TU Krohne, NK Stratmann, J Kopitz, FG Holz Experimental eye research 90 (3), 465-471, 2010 | 175 | 2010 |
Calix[n]arene‐Based Glycoclusters: Bioactivity of Thiourea‐Linked Galactose/Lactose Moieties as Inhibitors of Binding of Medically Relevant Lectins to a … S André, F Sansone, H Kaltner, A Casnati, J Kopitz, HJ Gabius, R Ungaro ChemBioChem 9 (10), 1649-1661, 2008 | 171 | 2008 |
Effects of lipid peroxidation-related protein modifications on RPE lysosomal functions and POS phagocytosis E Kaemmerer, F Schutt, TU Krohne, FG Holz, J Kopitz Investigative ophthalmology & visual science 48 (3), 1342-1347, 2007 | 164 | 2007 |
Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AβPP-overexpressing mice K Plaschke, J Kopitz, M Siegelin, R Schliebs, M Salkovic-Petrisic, ... Journal of Alzheimer's disease 19 (2), 691-704, 2010 | 159 | 2010 |
Unique Conformer Selection of Human Growth-Regulatory Lectin Galectin-1 for Ganglioside GM1 versus Bacterial Toxins, HC Siebert, S André, SY Lu, M Frank, H Kaltner, JA Van Kuik, ... Biochemistry 42 (50), 14762-14773, 2003 | 153 | 2003 |
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy‐mediated proteolysis in human retinal pigment epithelial cells T Ryhänen, JMT Hyttinen, J Kopitz, K Rilla, E Kuusisto, E Mannermaa, ... Journal of cellular and molecular medicine 13 (9b), 3616-3631, 2009 | 151 | 2009 |
Heat shock proteins as gatekeepers of proteolytic pathways—implications for age-related macular degeneration (AMD) K Kaarniranta, A Salminen, EL Eskelinen, J Kopitz Ageing research reviews 8 (2), 128-139, 2009 | 148 | 2009 |
Proteome analysis of lipofuscin in human retinal pigment epithelial cells F Schutt, B Ueberle, M Schnölzer, FG Holz, J Kopitz FEBS letters 528 (1-3), 217-221, 2002 | 143 | 2002 |
Olanzapine plasma concentration, average daily dose, and interaction with co-medication in schizophrenic patients N Bergemann, A Frick, P Parzer, J Kopitz Pharmacopsychiatry 37 (02), 63-68, 2004 | 126 | 2004 |