Commensal microbiota is fundamental for the development of inflammatory pain FA Amaral, D Sachs, VV Costa, CT Fagundes, D Cisalpino, TM Cunha, ... Proceedings of the National Academy of Sciences 105 (6), 2193-2197, 2008 | 328 | 2008 |
NLRP3 inflammasome–mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout FA Amaral, VV Costa, LD Tavares, D Sachs, FM Coelho, CT Fagundes, ... Arthritis & Rheumatism 64 (2), 474-484, 2012 | 256 | 2012 |
Morphine peripheral analgesia depends on activation of the PI3Kγ/AKT/nNOS/NO/KATP signaling pathway TM Cunha, D Roman-Campos, CM Lotufo, HL Duarte, GR Souza, ... Proceedings of the National Academy of Sciences 107 (9), 4442-4447, 2010 | 237 | 2010 |
Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway D Sachs, FQ Cunha, SH Ferreira Proceedings of the National Academy of Sciences 101 (10), 3680-3685, 2004 | 232 | 2004 |
Anti-inflammatory effects of the activation of the angiotensin-(1–7) receptor, MAS, in experimental models of arthritis KD da Silveira, FM Coelho, AT Vieira, D Sachs, LC Barroso, VV Costa, ... The Journal of Immunology 185 (9), 5569-5576, 2010 | 200 | 2010 |
Tumour necrosis factor-α, interleukin-1β and interleukin-8 induce persistent mechanical nociceptor hypersensitivity D Sachs, FQ Cunha, S Poole, SH Ferreira Pain 96 (1-2), 89-97, 2002 | 200 | 2002 |
The chemokine receptors CXCR1/CXCR2 modulate antigen‐induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature FM Coelho, V Pinho, FA Amaral, D Sachs, VV Costa, DH Rodrigues, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2008 | 185 | 2008 |
Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection DG Souza, CT Fagundes, LP Sousa, FA Amaral, RS Souza, AL Souza, ... Proceedings of the National Academy of Sciences 106 (33), 14138-14143, 2009 | 150 | 2009 |
The role of PKA and PKCε pathways in prostaglandin E2‐mediated hypernociception D Sachs, CF Villarreal, FQ Cunha, CA Parada, SH Ferreira British journal of pharmacology 156 (5), 826-834, 2009 | 99 | 2009 |
TNF-α, IL-1β, IL-6, and cinc-1 levels in rat brain after meningitis induced by Streptococcus pneumoniae T Barichello, I dos Santos, GD Savi, LR Simões, T Silvestre, CM Comim, ... Journal of neuroimmunology 221 (1-2), 42-45, 2010 | 86 | 2010 |
Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain ML Vale, VM Benevides, D Sachs, GAC Brito, FAC da Rocha, S Poole, ... British Journal of Pharmacology 143 (7), 833, 2004 | 84 | 2004 |
The role of NaV1. 8 sodium channel in the maintenance of chronic inflammatory hypernociception CF Villarreal, D Sachs, F de Queiroz Cunha, CA Parada, SH Ferreira Neuroscience letters 386 (2), 72-77, 2005 | 77 | 2005 |
Tumor necrosis factor alpha (TNF-α) levels in the brain and cerebrospinal fluid after meningitis induced by Streptococcus pneumoniae T Barichello, I Dos Santos, GD Savi, AF Florentino, C Silvestre, ... Neuroscience letters 467 (3), 217-219, 2009 | 69 | 2009 |
The critical role of leukotriene B4 in antigen-induced mechanical hyperalgesia in immunised rats JM Cunha, D Sachs, CA Canetti, S Poole, SH Ferreira, FQ Cunha British journal of pharmacology 139 (6), 1135, 2003 | 68 | 2003 |
Cooperative role of tumour necrosis factor‐α, interleukin‐1β and neutrophils in a novel behavioural model that concomitantly demonstrates articular inflammation and … D Sachs, FM Coelho, VV Costa, F Lopes, V Pinho, FA Amaral, TA Silva, ... British journal of pharmacology 162 (1), 72-83, 2011 | 63 | 2011 |
Glycosaminoglycan analogs as a novel anti-inflammatory strategy IC Severin, A Soares, J Hantson, M Teixeira, D Sachs, D Valognes, ... Frontiers in immunology 3, 293, 2012 | 58 | 2012 |
The peripheral pro-nociceptive state induced by repetitive inflammatory stimuli involves continuous activation of protein kinase A and protein kinase C epsilon and its NaV1. 8 … CF Villarreal, D Sachs, MI Funez, CA Parada, F de Queiroz Cunha, ... Biochemical pharmacology 77 (5), 867-877, 2009 | 50 | 2009 |
Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP‐sensitive K+ channel pathway GAC Brito, D Sachs, FQ Cunha, ML Vale, CMC Lotufo, SH Ferreira, ... European Journal of Neuroscience 24 (4), 1175-1181, 2006 | 38 | 2006 |
Mechanical hypernociception in experimental autoimmune encephalomyelitis DH Rodrigues, D Sachs, AL Teixeira Arquivos de neuro-psiquiatria 67, 78-81, 2009 | 33 | 2009 |
Depressive-like-behavior and proinflamatory interleukine levels in the brain of rats submitted to pneumococcal meningitis T Barichello, I Dos Santos, GD Savi, LR Simões, JS Generoso, ... Brain research bulletin 82 (5-6), 243-246, 2010 | 27 | 2010 |