Genetic Incorporation of a Small, Environmentally Sensitive, Fluorescent Probe into Proteins in Saccharomyces cerevisiae HS Lee, J Guo, EA Lemke, RD Dimla, PG Schultz Journal of the American Chemical Society 131 (36), 12921-12923, 2009 | 239 | 2009 |
A genetically encoded fluorescent probe in mammalian cells A Chatterjee, J Guo, HS Lee, PG Schultz Journal of the American Chemical Society 135 (34), 12540-12543, 2013 | 228 | 2013 |
Evolution of amber suppressor tRNAs for efficient bacterial production of proteins containing nonnatural amino acids J Guo, CE Melançon III, HS Lee, D Groff, PG Schultz Angewandte Chemie, 9312-9315, 2009 | 199 | 2009 |
Protein evolution with an expanded genetic code CC Liu, AV Mack, ML Tsao, JH Mills, HS Lee, H Choe, M Farzan, ... Proceedings of the National Academy of Sciences 105 (46), 17688-17693, 2008 | 192 | 2008 |
Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe HS Lee, G Spraggon, PG Schultz, F Wang Journal of the American Chemical Society 131 (7), 2481-2483, 2009 | 148 | 2009 |
Two-dimensional IR spectroscopy of protein dynamics using two vibrational labels: A site-specific genetically encoded unnatural amino acid and an active site ligand MC Thielges, JY Axup, D Wong, HS Lee, JK Chung, PG Schultz, ... The Journal of Physical Chemistry B 115 (38), 11294-11304, 2011 | 123 | 2011 |
Biosynthesis of a site-specific DNA cleaving protein HS Lee, PG Schultz Journal of the American Chemical Society 130 (40), 13194-13195, 2008 | 110 | 2008 |
A type-II kinase inhibitor capable of inhibiting the T315I “gatekeeper” mutant of Bcr-Abl HG Choi, P Ren, F Adrian, F Sun, HS Lee, X Wang, Q Ding, G Zhang, ... Journal of medicinal chemistry 53 (15), 5439-5448, 2010 | 87 | 2010 |
Protein–DNA photo-crosslinking with a genetically encoded benzophenone-containing amino acid HS Lee, RD Dimla, PG Schultz Bioorganic & medicinal chemistry letters 19 (17), 5222-5224, 2009 | 70 | 2009 |
Genetic incorporation of l-dihydroxyphenylalanine (DOPA) biosynthesized by a tyrosine phenol-lyase S Kim, BH Sung, SC Kim, HS Lee Chemical Communications 54 (24), 3002-3005, 2018 | 58 | 2018 |
Compounds and compositions as protein kinase inhibitors T Sim, HS Lee, P Ren, Q Ding, Y Liu, B Li, L Li, X Wang, T Uno, G Zhang, ... US Patent 7,642,255, 2010 | 51 | 2010 |
Analysis of protein–protein interaction in a single live cell by using a FRET system based on genetic code expansion technology SH Park, W Ko, HS Lee, I Shin Journal of the American Chemical Society 141 (10), 4273-4281, 2019 | 49 | 2019 |
Development of a simple method for protein conjugation by copper-free click reaction and its application to antibody-free Western blot analysis S Jang, K Sachin, H Lee, DW Kim, HS Lee Bioconjugate chemistry 23 (11), 2256-2261, 2012 | 46 | 2012 |
Compounds and compositions as protein kinase inhibitors T Sim, HS Lee, P Ren, Q Ding, G Zhang, Y Liu, X Wang, T Uno, B Li, L Li, ... US Patent 7,371,750, 2008 | 44 | 2008 |
Evolution of iron (II)‐finger peptides by using a bipyridyl amino acid M Kang, K Light, H Ai, W Shen, CH Kim, PR Chen, HS Lee, EI Solomon, ... ChemBioChem 15 (6), 822-825, 2014 | 43 | 2014 |
Compounds and compositions as protein kinase inhibitors T Sim, NS Gray, HS Lee, Y Liu, P Ren, S You, Q Zhang, Q Ding, X Wang, ... US Patent App. 11/814,912, 2009 | 41 | 2009 |
F-18 labeled RGD probes based on bioorthogonal strain-promoted click reaction for PET imaging HL Kim, K Sachin, HJ Jeong, W Choi, HS Lee, DW Kim ACS Medicinal Chemistry Letters 6 (4), 402-407, 2015 | 39 | 2015 |
Development of a universal glycosyltransferase assay amenable to high-throughput formats HS Lee, JS Thorson Analytical biochemistry 418 (1), 85-88, 2011 | 32 | 2011 |
A Glycoengineered enzyme with multiple Mannose-6-phosphates is internalized into diseased cells to restore its activity in lysosomes JY Hyun, S Kim, HS Lee, I Shin Cell chemical biology 25 (10), 1255-1267. e8, 2018 | 31 | 2018 |
Engineering a periplasmic binding protein for amino acid sensors with improved binding properties W Ko, S Kim, HS Lee Organic & biomolecular chemistry 15 (41), 8761-8769, 2017 | 31 | 2017 |